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Novartis drug pasireotide LAR shows superior efficacy
Patients on pasireotide (SOM230) LAR were 63% more likely to achieve full biochemical control than those on Sandostatin LAR, the current standard of care Acromegaly, a rare endocrine disorder c

Retention of radioactive iodine in serious NPP accidents
The Paul Scherrer Institute and industrial company CCI AG have signed a licencing agreement for iodine filtration processes In the nuclear disaster at Fukushima in Japan last year, the radioactive compounds that escaped from the plant caused both human and environmental damage.

Umsatzwachstum in anspruchsvollem Umfeld
Auftragsplus von 2% 1 (organisch unverändert 2 )und Umsatzzuwachs von 8% (organisch 6%) gegenüber Q1 2011 Zürich, Schweiz, 25.

A protein that regulates fat cell production and cell division
EPFL scientists have teased out the role that a protein known as SMRT plays in regulating the production of fat cells. And in the process, they made another, unexpected discovery; this protein also plays a critical role in the division of cells that ultimately store fat. How does the body produce fat cells? EPFL scientists have uncovered the role of SMRT, a protein involved in regulating this phenomenon.

The presence of water changes the structure of an antibiotic
EPFL chemists have shown how the three-dimensional shape of an antibiotic changes when it is in an aqueous environment. This could lead to a better understanding of how drugs interact with biological molecules. Like a key inserted into a lock, the molecules in drugs bind with and act upon biomolecules.

DuPont des Matériaux Award 2012 - Antonin Faes
RedOx Stability of Anode Supported Solid Oxide Fuel Cells. Thèse EPFL, no 4893 (2011). Dir.: Jan Van herle, Aïcha Hessler-Wyser.

EPFL de doctorate award 2012 - Oleg Vechorkin
A Well-Defined Ni Pincer Catalyst for Cross Coupling of Non-Activated Alkyl Halides and Direct C-H Alkylation.

La virulence d’un champignon dévastateur des pins enfin décryptée
Lassaâd Belbahri, biologiste au Laboratoire de biologie du sol de l'UniNE dirigé par Edward Mitchell, a participé à une vaste étude internationale pour décrypter le génome d'un champignon du genre

Insights into Intrastrand Cross-Link Lesions of DNA
Insights into Intrastrand Cross-Link Lesions of DNA from QM/MM Molecular Dynamics Simulations. DNA damages induced by oxidative intrastrand cross-links have been the subject of intense research during the past decade.

Data in NEJM shows Novartis drug Signifor is first therapy to provide rapid, durable benefit for Cushing’s disease patients in Phase III study
Study met primary endpoint showing Signifor (pasireotide) normalized cortisol overproduction , a critical factor in controlling the debilitating endocrine disorder , , Cortisol levels decreased quickly in the majority of patients and levels were normalized in 26.3% of patients treated with pasireotide 900µg twice daily Results showed pasireotide improved key clinical manifestations of the disease, including reductions in bl

CERN experiment makes spectroscopic measurement of antihydrogen
CERN experiment makes spectroscopic measurement of antihydrogen Geneva, 7 March 2012. In a paper published online today by the journal Nature , the ALPHA collaboration at CERN 1 reports an important milestone on the way to measuring the properties of antimatter atoms. This follows news reported in June last year that the collaboration had routinely trapped antihydrogen atoms for long periods of time.

Wie Chemotherapie besser wirkt
Forscher der Universität Zürich finden eine zelluläre Bremse, die Krebszellen vor Chemotherapeutika schützt - und sie zeigen, mit welchen Medikamenten diese ausser Betrieb gesetzt werden kann. Ihre Studie liefert die molekulare Grundlage für vielversprechende therapeutische Fortschritte und ist in der Fachpublikation «Nature Structural and Molecular Biology» erschienen.

Lehrlinge festigen ihr chemisches Wissen in Theorie und Praxis
Lehrlinge festigen ihr chemisches Wissen in Theorie und Praxis Nach dem Erfolg im vergangenen Jahr fand vom 6. bis 17. Februar die zweite Durchführung eines überbetrieblichen Kurses für angehende LaborantInnen aus Farb- und Lackverarbeitenden Betrieben statt.

ABB meldet solide Performance im vierten Quartal, Konzerngewinn steigt 2011 um 24%
Zürich, Schweiz, 16. Februar 2012 - ABB verzeichnete im vierten Quartal 2011 eine Steigerung der Rentabilität dank eines kräftigen Umsatzwachstums sowie konsequenten Kosteneinsparungen.

Ces protéines qui protègent notre génome
Des chercheurs de l'Université de Genève (UNIGE) ont découvert le rôle crucial de deux protéines dans la constitution d'un «bouclier anti-enzymes» cellulaire.

Schweizer Forscher stellen erstmals zweidimensionale Polymere her
«Nature Chemistry» präsentiert Aufsehen erregende Ergebnisse in Synthese-Chemie Für eine kleine Sensation in der synthetischen Chemie sorgen Wissenschaftler der ETH Zürich und der Empa. Erstmals ist es gelungen, regelmässig angeordnete zweidimensionale Polymere herzustellen, die eine Art «molekularer Teppich» im Nanometermassstab bilden.

Antimalarial successful joint research
Malaria remains a scourge of mankind, and the protozoan parasite responsible for the most virulent form of the disease, Plasmodium falciparum, is developing resistance against even the most recent molecules in the antimalarial arsenal.

SPARC-Koordinationsbüro neu an der ETH Zürich
Das internationale Projekt für Atmosphären- und Klimaforschung SPARC (Stratospheric Processes And their Role in Climate) verlegte sein Koordinationsbüro von Kanada in die Schweiz.

La plus prestigieuse bourse de promotion du Conseil européen de la recherche pour un chercheur en chimie des polymères
Le Professeur Christophe Weder, directeur de l'Institut Adolphe Merkle, obtient le "ERC-Advanced Investigator Grant" du Conseil européen de la recherche (European Research Council, ERC).

It works: Ultrafast magnetic processes observed “live” using an X-ray laser
In first-of-their-kind experiments performed at the American X-ray laser LCLS, a collaboration led by researchers from the Paul Scherrer Institute has been able to precisely follow how the magnetic structure of a material changes. The study was carried out on cupric oxide (CuO). The change of structure was initiated by a laser pulse, and then, with the help of short X-ray pulses, near-instantaneous images were obtained at different points in time for individual intermediate steps during the process.

A cobalt complex redox shuttle for dye-sensitized solar cells
A cobalt complex redox shuttle for dye-sensitized solar cells with high open-circuit potentials. Dye-sensitized solar cells are a promising alternative to traditional inorganic semiconductor-based solar cells.

DNS-Synthese im lebenden Organismus sichtbar machen
Forscher der Universität Zürich haben eine neue Substanz entdeckt, mit der es möglich wird, die DNS im lebenden Organismus zu markieren und so die Synthese von Biomolekülen im vollständigen Organismus sichtbar zu machen. Mit Hilfe dieses Verfahrens können Virusinfektionen oder Gewebewucherungen, wie sie bei der Krebsentstehung vorkommen, identifiziert und neue Wege bei der Medikamentenentwicklung eingeschlagen werden.  Viele zentrale Lebensvorgänge in den Zellen erfordern die Interaktion biologischer Makromoleküle.

Two Novartis Phase III studies show twice as many Ph+ CML patients achieve deeper levels of response with Tasigna compared to Glivec
ENESTcmr data show 23% of patients switched to Tasigna achieved undetectable levels of Bcr-Abl within 12 months compared to 11% who continued on Glivec Three-year ENESTnd data show 32% of newly diagnosed patients on Tasigna reached deepest levels of molecular response measured versus 15% on Glivec ENESTnd study also shows significantly fewer patients progressed to advanced stages of CML with Tasigna after three years,

Model shows how façade pollutants make it into the environment
Peak concentrations of biocides from house paint prove prevalent in urban river basins. Anti-fungal and anti-bacterial additives in house paint are present in dangerous quantities in the Vauchère river basin in the city of Lausanne, says a study to be presented the 9th of December, at the American Geophysical Union (AGU) conference in San Francisco.

Neue Leiterin für das Departement «Mobilität, Energie und Umwelt»
An seiner Sitzung vom 1. Dezember 2011 hat der ETH-Rat, das strategische Führungs- und Aufsichtsgremium des ETH-Bereichs, auf Antrag von Empa-Direktor Gian-Luca Bona die Chemikerin und Expertin für Luftschadstoffemissionen Brigitte Buchmann zum neuen Mitglied der Direktion ernannt.

Chemistry - A European Journal Volume 17, Issue 47, page 13106, 2011
Interfacial Complexation Reactions of Sr2+ with Octyl(phenyl)-N,N-diisobutylcarbamoyl methylphosphine Oxide for Understanding Its Extraction in Reprocessing Spent Nuclear Fuels. Stoichiometry and complexation equilibrium constants for the extraction of strontium from spent nuclear fuels at water room-temperature ionic liquid (RTIL) interfaces are very important for medicinal use of radioisotopes and remediation of contaminated environments.

Fluor gekonnt eingebaut
Der diesjährige Ruzicka-Preis geht an Ryan Gilmour, Professor am Laboratorium für Organische Chemie der ETH Zürich.