Thalamic control of cortical states

© 2012 EPFL

© 2012 EPFL

The group of Carl Petersen (LSENS - Laboratoire de traitement sensoriel ) investigated the impact of thalamus on ongoing cortical activity in the awake, behaving mouse. They demonstrate that the desynchronized cortical state during active behavior is driven by a centrally generated increase in thalamic action potential firing, which can also be mimicked by optogenetic stimulation of the thalamus.

The thalamus therefore is key in controlling cortical states.

 
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