Friedrich Miescher Institute for Biomedical Research

Friedrich Miescher Institute for Biomedical Research

Friedrich Miescher Institute for Biomedical Research   link
Ort: Basel
Maulbeerstrasse 66, 4058 Basel

Kategorie: Gesundheit
Angliederung: Novartis

Understanding the mechanisms of disease

The Friedrich Miescher Institute is devoted to fundamental biomedical research aimed at understanding the basic molecular mechanisms of health and disease. We communicate and patent our findings to enable their translation into medical application. The FMI focuses on the fields of
  • Epigenetics
  • Growth control
  • Neurobiology
In these fields, the FMI has gained international recognition as a center of excellence in innovative biomedical research.

Training young scientists

Biowissenschaften - Chemie - 19.04
Biowissenschaften - Chemie
The spatial organization of the genome is fundamental for the regulation of our genes and has to be established de novo during early embryogenesis. By combining powerful Drosophila genetics with 3D chromosome modelling, a collaboration between the Giorgetti group at the FMI and the MPI of Immunobiology and Epigenetics in Freiburg revealed a critical role of the epigenetic regulator HP1 in the establishment of 3D genome organization in the early Drosophila embryo.
Biowissenschaften - Gesundheit - 13.04
Biowissenschaften - Gesundheit

The protection of genome integrity of germ cells is essential for animal fertility. Researchers from the Grosshans group characterized a defense mechanism against selfish genetic elements in the C. elegans germline.

Biowissenschaften - 17.03

Spotlight on FMIers is a new series that showcases the lives, work and passions of the institute's researchers and support staff. In the first interview of the series, Esther Griesbach, a postdoctoral fellow in the group of Jeffrey Chao, tells us about herself, the fascination with RNA and what she learned about embarking on a new research journey in COVID times.

Biowissenschaften - Chemie - 18.02
Biowissenschaften - Chemie

During development, scores of molecular signals prod cells to take on specialized identities and functions.

Biowissenschaften - 8.02

Chromatin remodelers are needed to take nucleosomes away from DNA in order to make room for transcription factors to bind, and regulate the activity of our genes.

Karriere - 28.01

FMI Director Emeritus and Group Leader Emeritus, Susan Gasser, has been elected director of the Foundation of the Swiss Institute for Experimental Cancer (ISREC) by the Foundation Council. The ISREC Foundation has contributed to significant discoveries in oncology, and actively and substantially participates in the fight against cancer.

Biowissenschaften - Karriere - 6.04

April 6, 2021 We are pleased to announce the latest FMI winners of prestigious research fellowships, including EMBO, Maria Sklodowska-Curie Actions (MSCA), Human Frontier Science Program (HFSP) and Boehringer Ingelheim Funds (BIF).

Biowissenschaften - Psychologie - 3.03
Biowissenschaften - Psychologie

The brain's emotion-processing center — the amygdala — is one of several brain regions involved in social behavior.

Biowissenschaften - 16.02

In eukaryotes, histones are often modified and evicted at site of DNA double-strand breaks in order to facilitate end-resection and break repair. Together with the protein analysis facility of the FMI, the Gasser group has quantified massive changes in the chromatin associated proteome in response to DNA damage.

Gesundheit - Biowissenschaften - 1.02
Gesundheit - Biowissenschaften

The generation of antibodies in B-cells takes place in a dynamic structure that forms during infections, the germinal center (GC).

Veranstaltung - Biowissenschaften - 25.01
Veranstaltung - Biowissenschaften

FMI group leader Prisca Liberali, who is also a Professor at the University of Basel, receives the Friedrich Miescher Award 2021 for her research on design principles of tissue organization.

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