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Results 1 - 20 of 32.


Health - Pharmacology - 18.09.2020
Increasing the effectiveness of immunotherapy against skin cancer
Increasing the effectiveness of immunotherapy against skin cancer
Researchers at the University of Bern have discovered a mechanism in the body's own immune system which is responsible for the maturing and activation of immune cells. In the fight against skin cancer, the results have the potential to help immunotherapy succeed, even for patients on whom it previously had no effect.

Health - Pharmacology - 15.09.2020
Only One Third of Children Receive Appropriate Malaria Care
Only One Third of Children Receive Appropriate Malaria Care
Despite lots of progress made in the past decade, more than 270,000 children die from Malaria each year. Most of these deaths could be avoided through timely diagnosis and treatment. Despite better availability of tests and medication, a new study shows that large gaps remain in the quality of malaria care for children.

Pharmacology - Life Sciences - 04.08.2020
Blood-thinner with no bleeding side-effects is here
Blood-thinner with no bleeding side-effects is here
In a study led by EPFL, scientists have developed a synthetic blood-thinner that, unlike all others, doesn't cause bleeding side-effects. The highly potent, highly selective, and highly stable molecule can suppress thrombosis while letting blood clot normally following injury. Patients who suffer from thrombosis, pulmonary embolism or stroke are usually put on drugs that help their blood flow more smoothly through their body.

Pharmacology - Chemistry - 31.07.2020
Towards faster drug design
Towards faster drug design
A powerful new computational tool to identify the most promising pharmacological compounds and thus allow a much faster "screening". That is what has been developed thanks to the research carried out by Prof. Vittorio Limongelli's group of USI Faculty of Biomedical Sciences in collaboration with Prof. Siewert Marrink's group of University of Groningen (Netherlands).

Health - Pharmacology - 30.07.2020
New approach for targeted cancer immunotherapy
New approach for targeted cancer immunotherapy
A new study from researchers at the University of Basel demonstrates that a novel cancer immunotherapy, based on a locally focused activation of immune cells, could help to more efficiently eradicate tumor cells and reduce side effects. Cancer immunotherapies make use of the ability of the immune system to attack cancer cells: they unleash the killer function of T cells, which then attack and eradicate the cancer cells.

Health - Pharmacology - 23.07.2020
Iron deficiency during infancy reduces vaccine efficacy
About 40 percent of children around the globe suffer from anaemia because they do not consume enough iron. Now, studies by ETH researchers show that iron deficiency also reduces the protection provided by vaccinations. Despite the fact that global immunisation programmes are now reaching more people than ever, about 1.5 million children still die every year from diseases that vaccination could have prevented.

Health - Pharmacology - 22.07.2020
Primary care physicians during the COVID Epidemic-19
With a study covering 1,500 ambulatory patients, a team from the University of Geneva is highlighting the crucial role that general practitioners could play in the control of COVID-19. The global crisis triggered by COVID-19 has led governments to rely on the expertise of specialists in defining health emergency policies.

Pharmacology - Health - 15.07.2020
Blueprint of Oxytocin Receptor Facilitates Development of New Autism Drugs
Blueprint of Oxytocin Receptor Facilitates Development of New Autism Drugs
Oxytocin plays a role in various mental health and sexual reproduction disorders. Researchers at the University of Zurich have now determined the three-dimensional structure of the oxytocin receptor to which the hormone binds. This knowledge could promote the development of novel drugs to treat a variety of diseases.

Health - Pharmacology - 10.07.2020
Basel study: Why lopinavir and lopinavir and hydroxychloroquine do not work on Covid-19
Basel study: Why lopinavir and lopinavir and hydroxychloroquine do not work on Covid-19
Lopinavir is a drug against HIV, hydroxychloroquine is used to treat malaria and rheumatism. Until recently, both drugs were regarded as potential agents in the fight against the coronavirus SARS-CoV-2. A research group from the University of Basel and the University Hospital has now discovered that the concentration of the two drugs in the lungs of Covid-19 patients is not sufficient to fight the virus.

Pharmacology - Life Sciences - 11.06.2020
Solving a Parkinson's disease puzzle through protein design
EPFL researchers, in collaboration with UTSW and UCSD scientists, have developed a computational protein design approach, and used it to obtain the first ever high-resolution structure of an activated dopamine receptor in its natural cell membrane environment. The breakthrough will open up a new dimension in drug discovery for Parkinson's disease and perhaps other disorders.

Health - Pharmacology - 05.06.2020
Gene therapy to reverse vision loss in macular degeneration
Gene therapy to reverse vision loss in macular degeneration
Researchers have developed a strategy that has the potential to improve vision in patients with macular degeneration in the future. Using a gene therapy, they sensitized blind retinas of mice and human organ donors to near-infrared light. The team based at the Institute of Molecular and Clinical Ophthalmology Basel (IOB) has published its results .

Health - Pharmacology - 28.05.2020
Geneva study against SARS-CoV-2 gets underway
Geneva study against SARS-CoV-2 gets underway
Geneva University Hospitals (HUG), the University of Geneva , the Infectious Disease Research Centre at Laval University in Quebec (Canada) and MaxiVAX - a Geneva-based company specialising in biotechnology - are working together to develop a SARS-CoV-2 vaccine. This joint research programme aims to create a vaccine combining an immunostimulator and a specific coronavirus target, namely the spike surface protein.

Health - Pharmacology - 21.05.2020
Mastocytosis drug improves symptoms and quality of life
Mastocytosis drug improves symptoms and quality of life
From itching, abdominal pain and exhaustion to unconsciousness: the drug midostaurin can help alleviate these symptoms and improve quality of life in patients with mastocytosis. This has been proven by a research group at the University of Basel. Their findings have been published in the Journal of Allergy and Clinical Immunology.

Health - Pharmacology - 14.05.2020
Molecular Signatures can Predict the Efficacy of Malaria Vaccines
Molecular Signatures can Predict the Efficacy of Malaria Vaccines
A new study reveals that it is possible to identify those individuals that will be protected by the malaria vaccine before its administration. The researchers also found that boosting the immune system before vaccination could potentially improve vaccine efficacy. The study was published yesterday in Science Translational Medicine by ISGlobal in partnership with the Swiss Tropical and Public Health Institute and other partners.

Life Sciences - Pharmacology - 11.05.2020
Peptides that can be taken as a pill
Peptides that can be taken as a pill
Peptides represent a billion-dollar market in the pharmaceutical industry, but they can generally only be taken as injections to avoid degradation by stomach enzymes. Scientists at EPFL have now developed a method to generate peptides that resist enzymatic degradation and can be taken orally. Peptides are short chains of amino acids that occur in our body, in plants or bacteria to control diverse functions.

Health - Pharmacology - 11.05.2020
IOR researchers suggest that androgen-deprivation treatments for prostate cancer could protect men from COVID-19
The so-called "androgen-deprivation" treatments used in prostate cancer therapy may have a protective effect against COVID-19. A study conducted by the Istitute of Oncology Research (IOR, affiliated to USI) based on health data obtained from the Veneto region in Italy has observed a lower risk of developing the coronavirus disease for men subject to this type of therapy.

Health - Pharmacology - 07.05.2020
Prostate cancer treatment may protect from COVID-19
Androgen-deprivation therapy could protect against infection with SARS-CoV-2 and against severe disease progression. This is suggested by a study led by a professor from the UniversitÓ della Svizzera Italiana and ETH Zurich. Male cancer patients have a 1.8-fold increased risk of COVID-19 infection compared to the whole male population and develop a more severe disease.

Health - Pharmacology - 30.04.2020
High Cost of Cancer Drugs Not Always Justified
High Cost of Cancer Drugs Not Always Justified
Do high prices of some cancer medicines have a higher benefit than those drugs with lower prices' An international UZH study has concluded that, in general, there is no correlation between costs of a cancer drugs and their clinical benefit. The researchers are therefore calling for the clinical benefit of drugs to be better reflected in pricing.

Health - Pharmacology - 23.04.2020
A new therapeutic target turns the immune system against lymphoma
A new therapeutic target turns the immune system against lymphoma
EPFL scientists have identified a key mechanism that tumor cells use to take advantage of and avoid detection from the immune system. Targeting this mechanism offers a new therapeutic strategy for cancers like Non-Hodgkin lymphoma. Non-Hodgkin lymphoma (NHL) is a group of cancers that originate in the lymph nodes and affect white blood cells of the immune system called B cells.

Pharmacology - Health - 21.04.2020
Into drugs and vaccines to combat Covid-19
Into drugs and vaccines to combat Covid-19
As the world anxiously awaits a remedy for the novel coronavirus, ETH Zurich is also involved in the search for active substances and vaccines. This overview sets out the therapeutic approaches pursued by ETH researchers. As yet, there is still no reliable treatment for Sars-CoV-2. However, scientists across Switzerland and worldwide are engaged in an intensive search for an effective agent against the pathogen responsible for the Covid-19 pandemic.