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Results 1 - 20 of 416.
Scientists at EPFL use cutting-edge imaging techniques to shed light on the progression of Parkinson's disease by studying how the main culprit, the protein alpha-synuclein, disrupts cellular metabolism. Parkinson's disease is a complex neurodegenerative disorder that leads to the deterioration of specific types of neurons in the brain, resulting in a number of motor and non-motor symptoms.
A team from the University of Geneva shows that disruptions to the circadian clock increase the risk of developing a neurodegenerative disease. Disturbances in sleep patterns and the internal biological clock are frequently associated with Parkinson's disease. However, the link between biological rhythm and neuronal degeneration remains unclear.
Researchers at ETH Zurich have developed a suction cup that allows medications to be absorbed through the mucosal lining of the cheeks. This new approach could spare millions of patients the pain and fear associated with injections. Many of today's medications belong to groups of relatively large molecules such as peptides.
Biodiversity is greatest in the tropics. That fact that it is hot and humid there plays an important role. However, climate alone cannot explain the global biodiversity patterns well. Researchers at the Swiss Federal Institute for Forest, Snow and Landscape Research have now tackled this old problem from a completely different angle - and identified a new, doubly important reason for high tropical diversity.
Through an innovative project in Sri Lanka, an EPFL researcher and a Sri Lankan researcher have demonstrated that construction practices in transition economies can operate more efficiently, sustainably and responsibly.
Scientists show that it is possible to make a femtosecond laser that fits in the palm of one's hand using a glass substrate. Is it possible to make a femtosecond laser entirely out of glass? That's the rabbit hole that Yves Bellouard , head of EPFL's Galatea Laboratory, went down after years of spending hours - and hours - aligning femtosecond lasers for lab experiments.
Although strict limits exist, batteries can still contain too many harmful ingredients such as mercury, cadmium and lead. The Federal Office for the Environment (FOEN) has therefore launched a control campaign. Empa has laid the foundations for this with a specially developed method for analyzing heavy metals .
An international team co-led by UNIGE and HUG has decoded the only protein that can be used to ''see'' neuroinflammation. This discovery will improve the understanding of neurological and psychiatric disease mechanisms. Inflammation is the sign that our body is defending itself against an aggression.
Researchers uncover an intricate protein network controlling asymmetrical development of organs in the embryo, providing insights into genetic disorders and fundamental biology. In order to keep track of their environment, cells use cilia, antenna-like structures that can sense a variety of stimuli, including the flow of fluids outside the cell.
People differ significantly in their memory performance. Researchers at the University of Basel have now discovered that certain brain signals are related to these differences. While it is well known that certain brain regions play a crucial role in memory processes, so far it has not been clear whether these regions exhibit different activities when it comes to storing Signals in brain regions and networks In certain brain regions including the hippocampus, the researchers found a direct association between brain activity during the memorization process and subsequent memory performance.
People differ in their memory performance. Researchers at the University of Basel have now discovered that certain brain signals are related to these differences . Certain brain regions play a crucial role in memory processes. However, it was previously unclear whether these regions show different activities in storing information in people with a good memory than in those with a weaker memory.
Evolutionary Biology Artificial intelligence (AI) can help plant scientists collect and analyze unprecedented volumes of data, which would not be possible using conventional methods. Researchers at the University of Zurich (UZH) have now used big data, machine learning and field observations in the university's experimental garden to show how plants respond to changes in the environment.
An extraordinary heat wave is assailing the world's oceans with an intensity that is surprising climate researchers. Environmental physicist Nicolas Gruber provides some context. Record temperatures in the Mediterranean. Huge heat wave in the North Atlantic. The temperature of the oceans at an all-time high.
Regeneration across complete spinal cord injuries reverses paralysis
A complete spinal cord injury leads to irreversible paralysis. Scientists at.NeuroRestore report in Science that they have developed a gene therapy that was proven in mice to stimulate nerve regrowth across such injuries and guide nerves to reconnect to their natural targets below the injuries in order to restore motor function.
A complete spinal cord injury leads to irreversible paralysis. Scientists at.NeuroRestore report in Science that they have developed a gene therapy that was proven in mice to stimulate nerve regrowth across such injuries and guide nerves to reconnect to their natural targets below the injuries in order to restore motor function.
New imaging technique ’sees’ virus move in unprecedented detail
Scientists have developed a novel imaging technique to capture rapid protein dynamics. The technique, a microsecond, time-resolved version of cryogenic electron microscopy, allows them to observe the behavior of a virus in unprecedented detail. Proteins are the workhorses of biological systems, carrying out their work with extraordinary precision and speed.
Scientists have developed a novel imaging technique to capture rapid protein dynamics. The technique, a microsecond, time-resolved version of cryogenic electron microscopy, allows them to observe the behavior of a virus in unprecedented detail. Proteins are the workhorses of biological systems, carrying out their work with extraordinary precision and speed.
At Empa, acoustics experts have been investigating for years how noise is generated by passenger and cargo trains - and which technical and structural measures are particularly effective to prevent or at least reduce it. Their findings have now been incorporated into the SILVARSTAR project resulting in a simulation tool for rail noise that can help in practice.
Researchers at ETH Zurich have developed a method that lets them genetically modify each cell differently in animals. This allows them to study in a single experiment what used to require many animal experiments. Using the new method, the researchers have discovered genes that are relevant for a severe rare genetic disorder.
A research team at the University of Basel and the SIB Swiss Institute of Bioinformatics uncovered a treasure trove of uncharacterised proteins. Embracing the recent deep learning revolution, they discovered hundreds of new protein families and even a novel predicted protein fold. The study has now been published in "Nature".
Strengthening artificial immune cells to fight cancer
Scientists in Western Switzerland have discovered how to improve the anti-tumour power of CAR-T cells, artificial immune ''super-cells'' used against blood cancers. Among available immunotherapies, the use of 'CAR-T' cells is proving extremely effective against certain blood cancers, but only in half of patients.
Scientists in Western Switzerland have discovered how to improve the anti-tumour power of CAR-T cells, artificial immune ''super-cells'' used against blood cancers. Among available immunotherapies, the use of 'CAR-T' cells is proving extremely effective against certain blood cancers, but only in half of patients.
A team from the University of Geneva and HEP Vaud has developed an innovative method for studying teaching authority and assessing its effectiveness. How does pedagogical authority operate in the classroom? A team from the University of Geneva and the University of Teacher Education, State of Vaud (HEP Vaud) has produced one of the first in-depth field studies on this subject.
News from the Lab is a selection of science news that are significant or interesting for a broad readership.
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