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Medicine/Pharmacology



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Medicine/Pharmacology - Life Sciences
20.04.2018
New Novartis analyses at AAN show siponimod’s efficacy on disability and cognition in secondary progressive MS patients
Analyses of the EXPAND study showed that siponimod (BAF312) reduced the risk of disability progression largely disassociated from relapses in patients with secondary progressive multiple sclerosis (SPMS)   In EXPAND, siponimod also had a meaningful benefit on patients' cognitive processing speed   Findings add to clinical evidence for siponimod in SPMS, an area with a high unmet need for well-tolerated and effective new therapies - Novartis toda
Medicine/Pharmacology
16.04.2018
Triple drug combination shows high activity against parasitic worm infections
Triple drug combination shows high activity against parasitic worm infections
Swiss TPH researchers were able to show high efficacy of a triple drug therapy against hookworm and whipworm in a clinical trial in school-aged children in Lao PDR.
Medicine/Pharmacology - Life Sciences
11.04.2018
Double hit on melanoma unlocks barrier to immunotherapy
Double hit on melanoma unlocks barrier to immunotherapy
Researchers at EPFL and UNIL have discovered a dangerous liaison between immune cells that limits the efficacy of immunotherapy in melanoma. But they also found a way to disrupt it. Immunotherapies are treatments that stimulate a patient's immune cells to attack the tumor. They can be very effective in melanoma - a common and aggressive form of skin tumor - but still fail in the majority of the patients.
Medicine/Pharmacology
11.04.2018
Tobacco smoking - not long-term marijuana use - associated with build-up of plaques in heart arteries
Tobacco smoking - not long-term marijuana use - associated with build-up of plaques in heart arteries
Tobacco smoking, but not marijuana use over time, was associated with plaque build-up in heart arteries in a study that followed men and women for over 25 years, according to a study led by the University of Bern. "We knew the effect of tobacco smoke, but not of marijuana smoke on subclinical plaque build-up in heart arteries (a marker of future heart attacks).
Innovation/Technology - Medicine/Pharmacology
05.04.2018
Using spent barley grain to lower the sugar content of certain foods
Using spent barley grain to lower the sugar content of certain foods
EPFL spin-off Embion Technologies has developed a soluble fiber powder made from barley residue from the beer-making process that can be used to reduce the sucrose content of a wide range of foods. This by-product also appears to lower cholesterol levels and reduce the risk of cardiovascular diseases.
Life Sciences - Medicine/Pharmacology
05.04.2018
Efficient genetic modification of immune cells
Efficient genetic modification of immune cells
A new method enables genes in living T-cells in mice to be modified quickly and efficiently. It makes use of plasmids, a tried-and-tested method of genetic engineering. Researchers from the Department of Biomedicine at the University of Basel and University Hospital Basel reported these findings in the Journal of Immunology.
Medicine/Pharmacology
03.04.2018
Attacking Flu Viruses from Two Sides
Attacking Flu Viruses from Two Sides
Fever, shivering, headaches, and joint pains - each year millions of people around the world are affected by the flu. While most people recover after a few days, the WHO estimates that each year between 250,000 and 500,000 people die from the disease. As there are only few effective treatment options, medical efforts have thus far focused on vaccination to combat the flu.
Medicine/Pharmacology
29.03.2018
Smartphone Applications to Improve Child Health
Smartphone Applications to Improve Child Health
New technologies are progressively transforming health care. Swiss TPH developed two generations of digital point of care systems that support clinical personnel in the diagnosis and care of sick children. Swiss TPH will actively participate at this year's Geneva Health Forum on "Precision Global Health in the Digital Age" from 10-12 April 2018.
Medicine/Pharmacology - Life Sciences
22.03.2018
Attacking lymphoma at the source
Attacking lymphoma at the source
The efficacy of target specific therapies in lymphoma is limited to subgroups of patients. EPFL scientists have identified a mechanism that confers resistance against a common therapy for lymphoma.
Medicine/Pharmacology
19.03.2018
LSD Blurs Boundaries between the experience of Self and Other
Virtually all mental health disorders come with difficulties in interpersonal relations that in the long run negatively affect the progression of the disease. The associated health an social restrictions can only be marginally improved by current forms of therapy. One of the reasons for this is that there has been very little research into the basic neurobiological principles and in particular the neurochemical mechanisms of these kinds of disorders.
Life Sciences - Medicine/Pharmacology
19.03.2018
Tiny implants for cells are functional in vivo
Tiny implants for cells are functional in vivo
For the first time, an interdisciplinary team from the University of Basel has succeeded in integrating artificial organelles into the cells of living zebrafish embryos. This innovative approach using artificial organelles as cellular implants offers new potential in treating a range of diseases, as the authors report in an article published.
Medicine/Pharmacology - Sport Sciences
15.03.2018
New Understanding of Parasite Biology Might Help Stop Malaria Transmission
New Understanding of Parasite Biology Might Help Stop Malaria Transmission
Researchers at Swiss TPH made an important step toward deeper understanding of how malaria blood stage parasites turn the switch to become transmissible to other humans. This knowledge is fundamental for future research aiming to interrupt malaria transmission. The results will be published on Friday 16 March 2018 in the multidisciplinary journal Science.
Sport Sciences - Medicine/Pharmacology
15.03.2018
New Understanding of Parasite Biology Might Help Stop Malaria Transmission
New Understanding of Parasite Biology Might Help Stop Malaria Transmission
Researchers at the Swiss Tropical and Public Health Institute and the University of Basel made an important step toward a deeper understanding of how malaria blood stage parasites turn the switch to become transmissible to other humans. This knowledge is fundamental for future research aiming to interrupt malaria transmission.
Medicine/Pharmacology - Life Sciences
08.03.2018
Inherited mutation leads to overproduction of EPO
Inherited mutation leads to overproduction of EPO
A newly-discovered hereditary mutation is responsible for an increased production of erythropoietin (EPO) in the blood. This mutation causes a messenger RNA (mRNA) that is not normally involved in the formation of proteins to be reprogrammed so that it produces EPO, thus abnormally increasing the number of red blood cells.
Medicine/Pharmacology - Chemistry
08.03.2018
A retinal implant that is more effective against blindness
EPFL researchers have developed a new type of retinal implant for people who have become blind due to the loss of photoreceptor cells in their retinas. The implant partially restores their visual field and can significantly improve their quality of life. Thirty-two million people around the world are blind.
Medicine/Pharmacology - Life Sciences
08.03.2018
Recovery from Spinal Cord Injuries Can Be Predicted
Recovery from Spinal Cord Injuries Can Be Predicted
A trauma to the spinal cord, quickly leads to a progressive loss of nerve tissue. This not only affects the injured area, but over time affects also other parts of the spinal cord and even the brain. These neurodegenerative changes can be explored in detail using magnetic resonance imaging.
Life Sciences - Medicine/Pharmacology
08.03.2018
Canadian researchers open a new front in the fight against MS
By Ross Neitz, University of Alberta A discovery led by scientists at the University of Alberta and McGill University is providing hope of a new therapeutic target in Multiple Sclerosis (MS) patients, which could one day be used to prevent the symptoms and progression of the disease. In examining donated human brain tissues, the researchers unexpectedly found that MS brains have extremely high content of a protein named calnexin, compared to those without MS.
Medicine/Pharmacology
06.03.2018
HIV in sub-Sahara Africa: Testing and Treatment Start at Home Improves Therapy Outcome
HIV in sub-Sahara Africa: Testing and Treatment Start at Home Improves Therapy Outcome
Home-based HIV testing and prompt treatment with antiretroviral therapy increases the number of patients under treatment as well as treatment success. This is the key result of a clinical trial in Lesotho carried out by the Swiss Tropical and Public Health Institute, in collaboration with SolidarMed and the Government of Lesotho.
Life Sciences - Medicine/Pharmacology
06.03.2018
Our circadian clock sets the rhythm for our cells' powerhouses
Our circadian clock sets the rhythm for our cells’ powerhouses
Cellular energy metabolism also follows the rhythm of the circadian clock. A University of Basel study has now shown exactly how this works by revealing the relationship between the circadian rhythm and the mitochondrial network for the first time. Countless genetically controlled clocks tick inside different parts of our bodies, such as the liver, kidneys and heart.
Medicine/Pharmacology - Environment/Sustainable Development
06.03.2018
Why rare plants are rare
Why rare plants are rare
Rare plant species suffer more from disease than commoner species. The fact that rare species are more susceptible to attack by micro-organisms living in the soil, such as fungi and bacteria, may in fact be one of the reasons they are rare. Biologists have been trying to work out why some species are rare, while others are common, since Darwin's time and a new study from researchers at the University of Bern provides a possible answer.
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