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Medicine/Pharmacology



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Medicine/Pharmacology - Life Sciences
24.01.2018
Unexpected Helpers in Wound Healing
Unexpected Helpers in Wound Healing
An essential step in skin wound healing is wound closure, which is why shortly after an injury occurs, blood coagulates and seals the wound.
Medicine/Pharmacology - Life Sciences
24.01.2018
Boosting cancer therapy with cross-dressed immune cells
Boosting cancer therapy with cross-dressed immune cells
Researchers at EPFL have created artificial molecules that can help the immune system to recognize and attack cancer tumors.
Medicine/Pharmacology - Agronomy/Food Science
17.01.2018
Medicine/Pharmacology - Agronomy/Food Science
17.01.2018
Bile acids fire up fat-burning
EPFL scientists have discovered a novel role for bile acids: converting energy-storing white fat depots into energy-expending beige fat. The study is published. Obesity arises from an imbalance between energy intake and energy expenditure. As a result, current treatments try to decrease calorie intake and/or increase energy expenditure.
Medicine/Pharmacology - Life Sciences
12.01.2018
Medicine/Pharmacology - Life Sciences
09.01.2018
Cluster of Resistant Tuberculosis Pathogen Discovered
Cluster of Resistant Tuberculosis Pathogen Discovered
Resistant tuberculosis pathogens are a regular part of the day-to-day business at the Swiss National Center for Mycobacteria (NZM) at the University of Zurich. And yet, the Mycobacterium tuberculosis found in a Somali asylum seeker in the refugee center in Chiasso in February 2016 was extraordinary: “These bacteria exhibited a new combination of resistance mutations against four different antibiotics that had never before been described,” says Peter Keller, Head of Diagnostics at NZM, who identified the germ.
Medicine/Pharmacology - Life Sciences
09.01.2018
New Biomarkers Predict Outcome of Cancer Immunotherapy
New Biomarkers Predict Outcome of Cancer Immunotherapy
Nowadays, melanoma and lung cancer can be combatted effectively through immunotherapy, which makes targeted use of the immune system's normal function of regularly examining the body's tissue for pathogens and damages. Specific inhibitors are used to activate immune cells in a way that makes them identify cancer cells as foreign bodies and eliminate them.
Life Sciences - Medicine/Pharmacology
27.12.2017
Bacteria acquire resistance from competitors
Bacteria acquire resistance from competitors
Bacteria not only develop resistance to antibiotics, they also can pick it up from their rivals. In a recent publication in "Cell Reports", Researchers from the Biozentrum of the University of Basel have demonstrated that some bacteria inject a toxic cocktail into their competitors causing cell lysis and death.
Medicine/Pharmacology - Computer Science/Telecom
26.12.2017
Looking back at 2017 (1/2)
Coral reefs that can survive global warming, an expedition around Antarctica, a booster for genetic research, a personnal virtual heart, a National Center for Data Science... Some of the EPFL's research and milestones that marked the year 2017.
Medicine/Pharmacology - Life Sciences
20.12.2017
Feasibility of Eliminating Rabies in Africa
Feasibility of Eliminating Rabies in Africa
The Swiss Tropical and Public Health Institute, together with European and African collaborators, carried out a mass dog vaccination in Chad and determined its effect on human rabies exposure. The study employed a bio-mathematical method for estimating the transmission dynamics of rabies. The researchers conclude that with political will and the necessary funding, elimination of rabies is possible in Africa.
Medicine/Pharmacology - Computer Science/Telecom
20.12.2017
New software can model natural light from the occupants' perspective
New software can model natural light from the occupants' perspective
OCUVIS, a visualization software developed by a soon-to-be-launched EPFL spin-off, lets architects simulate 3D building models to assess the performance of natural light indoors. After specifying the ambient conditions, architects can view the visual and non-visual characteristics of the resulting natural light in their designs.
Medicine/Pharmacology
20.12.2017
Feasibility of Eliminating Rabies in Africa
Feasibility of Eliminating Rabies in Africa
The Swiss Tropical and Public Health Institute, together with European and African collaborators, carried out a mass dog vaccination in Chad and determined its effect on human rabies exposure. The study employed a bio-mathematical method for estimating the transmission dynamics of rabies. The researchers conclude that with political will and the necessary funding, elimination of rabies is possible in Africa.
Physics/Materials Science - Medicine/Pharmacology
18.12.2017
Using gold nanoparticles to destroy viruses
Using gold nanoparticles to destroy viruses
EPFL researchers have created nanoparticles that attract viruses and, using the pressure resulting from the binding process, destroy them. This revolutionary approach could lead to the development of broad-spectrum antiviral drugs.  HIV, dengue, papillomavirus, herpes and Ebola - these are just some of the many viruses that kill millions of people every year, mostly children in developing countries.
Medicine/Pharmacology - Life Sciences
14.12.2017
The immune cells that help tumors instead of destroying them
The immune cells that help tumors instead of destroying them
EPFL scientists have discovered that neutrophils, a type of immune cell, can actually help lung tumors grow. The work is published in Cell Reports, and has enormous implications for cancer immunotherapy. Neutrophils inside lung adenocarcinoma tumors. On the left, neutrophils inside a mouse tumor are stained brown; on the right, neutrophils inside a human tumor are stained red (credit: E. Meylan/EPFL).
Life Sciences - Medicine/Pharmacology
13.12.2017
Protein Structure Could Unlock New Treatments for Cystic Fibrosis
Protein Structure Could Unlock New Treatments for Cystic Fibrosis
Cystic fibrosis is a severe hereditary disease of the lung, for which there is currently no cure. The underlying cause of the disease is a malfunction of the chloride channel CFTR, which prevents the secretion of chloride in certain body cells.
Life Sciences - Medicine/Pharmacology
13.12.2017
Cellular Self-Digestion Process Triggers Autoimmune Disease
Autophagy refers to a fundamental recycling process of cells that occurs in yeast, fungi, plants, as well as animals and humans. This process allows cells to degrade their own components and thus activate energy resources to be able to adapt to nutritional needs. In addition, autophagy plays a central role in steering an organism's immune response.
Medicine/Pharmacology - Life Sciences
11.12.2017
Novartis drug crizanlizumab shown to prolong time to patients’ first sickle cell pain crisis in subgroup analysis of SUSTAIN study
Investigational therapy crizanlizumab (SEG101, formerly SelG1) approximately doubled the time to first on-treatment sickle cell pain crisis, according to new subgroup analysis of Phase II SUSTAIN data Results were consistent across patient subgroups despite differences in disease severity, genotype or background therapy New findings for crizanlizumab, a potential disease-modifying, preventive treatment option for patients with sickle cell diseas
Medicine/Pharmacology - Life Sciences
11.12.2017
Liver Cancer: Lipid Synthesis Promotes Tumor Formation
Liver Cancer: Lipid Synthesis Promotes Tumor Formation
Lipid, also known as fat, is an optimal energy source and an important cell component. Much is required for the rapid and uncontrolled growth of cancer cells. Researchers from the Biozentrum of the University of Basel and from the University of Geneva have now discovered that the protein mTOR stimulates the production of lipids in liver tumors to satisfy the increased nutrient turnover and energy needs of cancer cells among other functions.
Medicine/Pharmacology - Physics/Materials Science
08.12.2017
Medicine/Pharmacology - Life Sciences
06.12.2017
Healthy mitochondria could stop Alzheimer's
Healthy mitochondria could stop Alzheimer's
Using a bioinformatics and experimental approach, scientists at EPFL have found that rendering mitochondria resistant to damage can halt diseases caused by amyloid toxicity, such as Alzheimer's disease. Alzheimer's disease is the most common form of dementia and neurodegeneration worldwide. A major hallmark of the disease is the accumulation of toxic plaques in the brain, formed by the abnormal aggregation of a protein called beta-amyloid inside neurons.
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