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Life Sciences - Health - 17.08.2019
Function from structure: the double life of a DUB
Function from structure: the double life of a DUB
Deubiquitinases (DUBs) play a general role removing protein-degrading ubiquitins throughout the cell and are not typically known for specificity. Analyzing the two protein complexes BRISC and BRCA1-A, which have the same DUB core but play different roles in human biology, the Thomä group - in a collaboration with the Novartis Institutes for BioMedical Research (NIBR) - showed that DUBs can have diversified targeting and regulatory functions.

Health - Life Sciences - 15.08.2019
Major award for two Bernese medical projects
Major award for two Bernese medical projects
Prestigious grants from the USA go to two Bernese researchers: the biomedical scientists Marianna Kruithof-de Julio and Robert Rieben were the only researchers in Switzerland to receive a grant under

Pharmacology - Life Sciences - 07.08.2019
Novartis stands behind Zolgensma (onasemnogene abeparvovec-xioi) for the treatment of children less than 2 years of age with spinal muscular atrophy
Basel, August 6, 2019 - Today the FDA released a statement addressing data integrity issues with the Biologics License Application (BLA) for Zolgensma (onasemnogene abeparvovec-xioi). First and foremost, we are fully confident in the safety, quality and efficacy of Zolgensma. The FDA supports the continued marketing and use of Zolgensma for patients with spinal muscular atrophy (SMA) less than 2 years of age.

Environment - Life Sciences - 30.07.2019
Buzzing with life
Buzzing with life
The ETH Zurich Zentrum and Hönggerberg campuses are not just the study and office spaces of the 30,000 members of ETH: they are also home to a variety of animals and plants.

Life Sciences - Health - 21.07.2019
150 years of DNA
150 years of DNA
DNA has become the icon of modern bioscience but few people realize that it was Friedrich Miescher, who - almost a century before Watson and Crick - laid the chemical groundwork for the molecular breakthroughs that followed. Today, 150 years after Miescher's first ‘discovery' of DNA, we want to highlight his remarkable work.

Life Sciences - Innovation / Technology - 16.07.2019
Evaluating the risks posed by synthetic biology
Last week, nearly 70 experts from around the world gathered at EPFL for a workshop on potential threats arising from synthetic biology.

Health - Life Sciences - 11.06.2019

Life Sciences - Health - 06.06.2019
How flow shapes bacterial biofilms
How flow shapes bacterial biofilms
EPFL biophysicists have taken a systematic look into how bacterial biofilms are affected by fluid flow. The findings can give us clues about the physical rules guiding biofilm architecture, but also about the social dynamics that shape evolution. Although we tend to think of them as solitary sojourners of the world, bacteria are actually very social organisms.

Life Sciences - 03.06.2019
Fathers Aid Development of Larger Brains
Fathers Aid Development of Larger Brains
The bigger the brain, the more intelligent a mammalian species is. Developing a large brain, though, requires a huge energy input.

Mathematics - Life Sciences - 23.05.2019

Life Sciences - Agronomy / Food Science - 08.05.2019
Enabling consumers to analyze their food's DNA
Enabling consumers to analyze their food's DNA
EPFL's Digital Epidemiology Lab held its first food DNA sequencing workshop last Saturday, in association with SwissDeCode and Hackuarium.

Health - Life Sciences - 07.05.2019
Roche presents data from the risdiplam pivotal FIREFISH and SUNFISH studies in spinal muscular atrophy at the 2019 AAN Annual Meeting
In the dose-finding Part 1 of FIREFISH, infants with Type 1 spinal muscular atrophy survive and achieve key milestones beyond those expected in the natural history of the disease New data from the dose-finding Part 1 of SUNFISH reinforce risdiplam as a promising investigational therapy for people with Type 2 or 3 spinal muscular atrophy No treatment-related safety findings leading to withdrawal seen to date in risdiplam trials Roche today announ

Health - Life Sciences - 05.05.2019
AveXis presented robust data at AAN demonstrating efficacy of Zolgensma in broad spectrum of spinal muscular atrophy (SMA) patients
Interim data reported for the first time from STRONG in SMA Type 2 showed rapid motor function gains and milestone achievements with intrathecal Zolgensma (onasemnogene abeparvovec-xioi; AVXS-101)  

Life Sciences - 02.05.2019

Life Sciences - Health - 16.04.2019
AveXis data reinforce effectiveness of Zolgensma in treating spinal muscular atrophy (SMA) Type 1
Ph 3 STR1VE data show prolonged event-free survival, early and rapid increases in CHOP-INTEND and significant milestone achievement in SMA Type 1, consistent with START trial   First-in-human biodist

Life Sciences - 10.04.2019
Showy Primates Have Smaller Testicles
Well-adorned or well-endowed ' but not both. Evolutionary biologists at the University of Zurich have for the first time demonstrated that male primates either have large testicles or showy ornaments. Developing both at the same time may simply take too much energy. Male primates are highly competitive, especially about one thing: fathering offspring.

Health - Life Sciences - 09.04.2019
Animal-assisted therapy improves social behavior in patients with brain injuries
Animal-assisted therapy improves social behavior in patients with brain injuries
Animal-assisted therapy can foster social competence in patients with brain injuries and increase their emotional involvement during therapy. These were the findings of a clinical trial conducted by psychologists from the University of Basel and published in the journal Scientific Reports. After a severe traumatic brain injury, patients often exhibit problems in their social behavior.

Life Sciences - Career - 08.04.2019
Interview with new group leader Guillaume Diss
Guillaume Diss joined the FMI as a new Quantitative Biology group leader on March 1. His research focuses on understanding the mechanisms whereby genetic variation translates into phenotypic variation - for example, in diseases.

Life Sciences - Agronomy / Food Science - 25.03.2019
Corinne Boss Takes Reins of ’Animals and Products of Animal Origin’ Competence Division at Agroscope
Corinne Boss is the new Head of Agroscope's 'Animals and Products of Animal Origin' Competence Division for Research Technology and Knowledge Transfer; in this capacity, she also becomes a Member of the Agroscope Executive Board. A biologist and official expert in animal health, Corinne Boss currently works at the Swiss Federal Office for Agriculture (FOAG) as a Research Scientist in the 'Products of Animal Origin and Livestock Breeding' Division.

Life Sciences - Health - 19.03.2019
Evolutionary nightmare: Parasites pass on their manipulatory characteristics
Evolutionary nightmare: Parasites pass on their manipulatory characteristics
Many parasites move from host to host several times during their life cycle, including the parasitic tapeworm Schistocephalus solidus , which infects three hosts altogether.

Life Sciences - 15.03.2019
Female roundworms produce clones of themselves
Female roundworms produce clones of themselves
In the Mesorhabditis belari roundworm, the sole purpose of males is to help females produce clones of themselves. This unique form of reproduction was recently described by an international research team with participation of Peter Meister from the Institute of Cell Biology of the University of Bern.

Life Sciences - Psychology - 13.03.2019
New Marie Curie and EMBO Fellows at the FMI
Five of our postdocs were recently awarded the prestigious EMBO and Maria Sklodowska-Curie Actions (MSCA) Fellowships.

Health - Life Sciences - 12.03.2019
EPFL software mines rich medical data while keeping it secure
MedCo , developed in the lab of EPFL professor Jean-Pierre Hubaux in collaboration with professor Bryan Ford 's DEDIS lab and the Lausanne University Hospital ( CHUV ), is the first operational system to protect sensitive patient data - including genetic information - so that it can be used collectively for crucial medical research.

Life Sciences - 11.03.2019

Life Sciences - Health - 27.02.2019
Model redefines the tree of life as we know it
Model redefines the tree of life as we know it
A new method shows that the relationships between living species, from bacteria to plants and animals, are different from previous estimates.

Health - Life Sciences - 27.02.2019
Bern Center for Precision Medicine founded
Bern Center for Precision Medicine founded
Precision medicine "tailored" to individual patients is regarded as the medicine of the future. It is already being practiced at the University of Bern and Inselspital, Bern University Hospital.

Environment - Life Sciences - 19.02.2019
Fly larvae make biowaste disposal more climate friendly
Fly larvae make biowaste disposal more climate friendly
As the world's population continues to grow, the piles of biowaste also tower higher and higher.

Life Sciences - 11.02.2019

Environment - Life Sciences - 11.02.2019
"The Arctic atmosphere is key to understanding climate change"
This summer, 40 international scientists will participate in the GLACE expedition around Greenland in order to study the effects of climate change in that region.

Life Sciences - 08.02.2019

Environment - Life Sciences - 30.01.2019
Urban biodiversity: Remarkable diversity of small animals in Basel gardens
Urban biodiversity: Remarkable diversity of small animals in Basel gardens
Gardens in urban areas can harbor a remarkable diversity of species. This has been found by researchers from the University of Basel in a field study carried out with the support of private garden owners from the Basel region. Furthermore, the research team shows that nature-friendly garden management and design can largely compensate for the negative effects of urbanization on biodiversity.

Environment - Life Sciences - 24.01.2019

Pharmacology - Life Sciences - 22.01.2019

Health - Life Sciences - 22.01.2019

Life Sciences - 21.01.2019
Octopus's Garden: The Stunning Life of Macroalgae
Octopus’s Garden: The Stunning Life of Macroalgae
The Botanical Garden of the University of Zurich is displaying large-format pictures of macroalgae taken by photographer Josh Westrich, bringing these maritime organisms into the tropical setting of UZH's greenhouses.

Health - Life Sciences - 15.01.2019

Environment - Life Sciences - 15.01.2019
EPFL goes to New Zealand to study melting glaciers
Four EPFL researchers will explore New Zealand's glacier-fed streams for two months, marking the first step in a global journey that will take them across 15 countries by 2021.

Life Sciences - 09.01.2019
Change of Teeth Causes Yo-Yo Effect in Elephants' Weight
Change of Teeth Causes Yo-Yo Effect in Elephants’ Weight
The weight of elephants living in zoos fluctuates over the course of their adult lives in cycles lasting around a hundred months, researchers at the University of Zurich have found. The fluctuation is linked to the particular pattern of tooth change in elephants, which results in them having more or less chewing surface available.
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