Mathematical Modelling to Inform Next-Generation Malaria Interventions

Development of novel interventions for malaria prevention must be accelerated to
Development of novel interventions for malaria prevention must be accelerated to meet current and future needs. Photo credit: Matthis Kleeb
Development of novel interventions for malaria prevention must be accelerated to meet current and future needs. Photo credit: Matthis Kleeb Global progress against malaria has stagnated and novel medical interventions are urgently needed. In a new publication, researchers from Swiss TPH and the Gates Medical Research Institute describe how modelling evidence is crucial for accelerating the development of new malaria vaccines, monoclonal antibodies and chemoprevention. Results were published today in Communications Medicine from Nature. With increasing threats of malaria drug and insecticide resistance, there is now a need for novel malaria interventions to improve public health. According to the study published in , using mathematical modeling to inform the development of new interventions, such as vaccines, can help accelerate progress in the fight against malaria. The models can provide insight into which characteristics of an intervention are most important for public health impact, and support decision-makers early on in the product development pipeline.
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