Zurich University of Applied Sciences ZHAW is one of Switzerland’s largest multidisciplinary universities of applied sciences, with over 13,000 students and 3,000 faculty and staff. The School of Life Sciences and Facility Management is located on an attractive campus on the left shore of the Lake of Zurich in Wädenswil. The Competence Center for Biocatalysis (CCBIO) at the Institute for Chemistry and Biotechnology (ICBT) is recruiting a Bioinformatician (100 %)
The successful candidate will be part of our effort to harness machine-learning driven enzyme engineering for the development of next-generation industrial biocatalysis.
Execution of innovative research projects in the field of industrial biocatalysis
Application and development of novel methods to leverage protein structure data for enzyme engineering
Implementing and utilizing state-of-the-art machine learning methods to gain insights from enzyme structure-activity relationships for improved experimental design
Statistical analysis of enzyme engineering data to validate experimental quality -
Developing and expanding the relevant laboratory infrastructure
PhD in bioinformatics, chemistry, biochemistry, computational biology, or equivalent combination of education and experience to perform independently at this level
Working knowledge of state-of-the-art bioinformatics, computational biology, and protein/small molecules modeling tools
Proficient in statistics and able to apply it to experimental design and analysis
Experience in modeling, de novo prediction, visualization and analysis of protein structures, small molecule docking and molecular dynamics of protein/ small molecules
Programming experience in Perl, Python, R and working knowledge of Rosetta or similar computational packages
Experience and proven expertise in analysis of large datasets
Experience in programming or using robotic systems tailored for high throughput screening of small molecule assays would be a plus
Experience in carrying out multiple sequence alignments, phylogenetic reconstruction, sequence similarity networks as well as processing, quality control and statistical analysis of internal and external biological data sets including Next Generation Sequencing (NGS) data would be a plus
We offer you a challenging task in an inspiring working environment with a motivated, young team.
For more information please contact Prof. Dr. Rebecca Buller, Head of Competence Center for Biocatalysis, +41 58 934 5438 or rebecca.bullerzhaw.ch .
To apply for this position, please use the online platform to send us your portfolio to the attention of Kathrin Tangemann, HR Consultant. Please note that we cannot consider applications sent by e-mail.