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Portfolio Operations Director

Lieu de travailBâle, Suisse du Nord-Ouest, Suisse

The Company

At Roche, we believe it is urgent to deliver medical solutions right now – even as we develop innovations for the future. We are passionate about transforming patients’ lives and we are daring in both decision and action. And we believe that good business means a better world. That is why we come to work each day. We commit ourselves to scientific rigour, unassailable ethics, and access to medical innovations for all. We do this today to build a better tomorrow.

Roche pRED (Pharma Research and Early Development) is one of four divisions within the Roche Group that make up the company’s research and early development activities. Roche pRED’s scientific work is organized within Discovery & Translational Medicine Areas (DTAs). Currently, the areas of focus include Immunology, Infectious Diseases and Ophthalmology; Neuroscience and Rare Diseases; and Oncology. The pRED community is made up of more than 2,200 scientists spanning the globe from Europe to North America and Asia.

With its long history in disorders of the nervous system and strengths across diverse disciplines, Roche is uniquely positioned to lead in transforming science to medicines for patients with disorders of the nervous system. The Neuroscience and Rare Diseases (NRD) Discovery and Translational Area (DTA) group currently has approximately 160 members based in Basel, Switzerland. The Roche NRD DTA in Basel and Genentech’s neuroscience group in South San Francisco operate in collaboration and in parallel.


Key responsibilities

  • Provide portfolio operational leadership aligned with the Global Head of Operations

  • Define portfolio strategies, operating models, operational plans and processes

  • Ensure processes and systems efficiency, consistency and integration into the larger pRED and Roche infrastructure

  • Design and implement tracking systems for portfolio performance and projection activities, as well as for budget and resources with our HR and Finance partners to achieve strategic direction and goals

  • Build and implement processes, metrics and tools for portfolio assessment, target selection, portfolio reviews, risk and resource planning. In particular, develop analytics and data visualizations to generate evidence and business insights that enable operational efficiency and targeted communications to stakeholders

  • Partner with and advise NRD leadership and governance bodies on portfolio status and direction to ensure transparent and informed decision-making to guide both near and long-term planning

  • Implement and maintain the processes that ensure the improvement of portfolio performance and productivity through proactive data analysis (historical and forecasted, internal and industry)

  • Support the implementation and delivery of the NRD Network disease area strategies. In particular, provide strategic and project inter-dependencies context to project squads to help create greater efficiencies

  • Own the business process for Department and Network leadership teams and portfolio review committees. In particular, prepare, organize, manage and facilitate meetings, sprints, think tanks, stand-ups and other agile meeting formats, including agenda setting, outcomes, and action items management

  • Ensure that the NRD portfolio updates are accurately reported within relevant decision bodies and support tools

  • Work with HR and Finance to coordinate FTE resource planning and the budget strategy

  • Coordinate and collaborate with communications groups, drafting communications on portfolio transitions, governance changes, people changes, publications, etc...

  • Typically acts as primary point-of-contact for all compliance matters



You have a deep and broad understanding of drug development, a track record of successfully managing large and complex pharmaceutical portfolios, and a strong knowledge of portfolio systems and processes.

  • Operational accomplishments. A key quality sought in our candidates will be significant accomplishments in portfolio operations, insights, processes and tools. A strong record of portfolio operational successes in research or clinical development efforts and evidence of senior responsibilities in the pharmaceutical setting will be important

  • Collaborative acumen. It is essential that the candidate is highly collaborative with the ability to work with peers and a large number of partners across the organization who are not in the line-of-command with the aim of improving the DTA operational performance and meeting our goals. The candidate has a track record of facilitating and encouraging multiple relationships across departments in line with matrix project responsibilities

  • Strategic experience. In partnership with other leaders in the NRD DTA, the candidate will support the implementation of the portfolio strategy for each NRD disease focused area. Hence, the candidate must have a strong strategic experience exploring immediate, mid-term and long-term opportunities and threats in research and development portfolios, evaluating options and risks, and proposing proactive steps to address them

  • Results orientation. The candidate is a thinker and a doer. The candidate will focus on key Network priorities and the delivery of Network portfolio goals. The ideal candidate will support the implementation of portfolio strategic priorities beyond expectations

  • Creativity. The candidate will have successfully engaged in dynamic and thriving teams in an environment that fosters creativity and innovation. The candidate will create a strong sense of team spirit in the organization, lead portfolio operations from the front, build effective matrix teams, and take ownership of NRD colleagues’ day-to-day issues


  • You have an advanced degree in science (a PhD in a related scientific discipline is favored), in mathematics/statistics, engineering, or business; ideally with a strong background in the life sciences. An MBA is preferred

  • You bring significant years of pharmaceutical industry experience in drug development across the value chain with at least 3+ years experience in portfolio management/performance analytics, resource planning, financial analysis/budgeting and process analytics in a high tech environment. Exceptional analytical, quantitative modeling and data visualization skills, using tools such as Tableau and Spotfire, are a plus

  • Evidence of strong strategic thinking and strategy development, ability to manage complexity and proven communication skills at all levels in the organization. Skilled at distilling complex/abstract problems into succinct strategic frameworks as well as execution plans

  • Collaborative individual, able to influence without authority and engage senior leaders and partners actively. Clearly articulate and communicate critical analytical findings to senior leadership and drug development teams. Able to influence using active listening, communication and facilitation skills

  • Proven ability to start and drive initiatives to successful outcomes in a cross-functional environment and influencing stakeholders across the organization. Able to switch between “big picture” and “detail oriented”

  • Strong emotional intelligence, communicating openly and respectfully, remaining resilient through changes, flexible and freely expressing creativity.

Nous offrons

Are you ready to apply? We are looking for a person who thinks beyond the job offered - someone who knows that this position can be a rare springboard to many other opportunities at Roche.

Roche embraces diversity and equal opportunity in a serious way. We are committed to building teams that represent a range of backgrounds, perspectives, and skills. The more inclusive we are, the better our work will be.

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Roche is an equal opportunity employer.

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