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Doctoral thesis in the field of controlled release systems for perivascular applications

University of Geneva
School of Pharmaceutical Sciences
WorkplaceGeneva, Lake Geneva region, Switzerland
Duration4 years
StartJune 2017

The laboratory of Pharmaceutical Technology of the School of Pharmaceutical Sciences at the University of Geneva (Switzerland) has an opening for a PhD position.
Thesis directors: Dr. Florence Delie and Dr. Olivier Jordan.


The failure of arterial bypass surgery due to postoperative vascular obstruction is a problem affecting millions of people annually. A preventive local treatment inhibiting the pathophysiological processes involved in the development of intimal hyperplasia may improve, on the long term, the patency of the vessel. Therefore, this thesis project focuses on the development, the physico-chemical characterization, in vitro and in vivo evaluation of systems with controlled release of active principle(s) for perivascular administration.

The work will involve developing gel formulations and encapsulating active ingredients in microparticles. Other innovative approaches will also be developed. The preparations will be fully characterized especially in terms of loading rate of the active compound(s), release kinetics and stability. The efficacy of the systems will be evaluated on cell culture and animal models.

This study involves a close collaboration between the laboratories of Pharmaceutical Technology and Biopharmacy of the EPGL at the University of Geneva and the department of vascular surgery of the hospital of Lausanne.


We are looking for a highly motivated candidate able to carry out an interdisciplinary research in an independent way, interacting with our collaborators. The candidate holds a master in Pharmaceutical sciences, Pharmacy, or an equivalent degree. The ideal candidate is highly motivated, inventive, team player, well organized and has an excellent command of English. The PhD student will have a position of part-time assistant He/she will participate to training and teaching for undergraduate students.
We offerThe salary will follow the standards of the Geneva-Lausanne School of Pharmacy.


Please send your application, deadline February 28, 2017 (resume, motivation letter and recommendation letter(s)) to Mrs Florence Von Ow-Lesniewski: Florence.VonOwunige.ch.
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