We are studying disorders of hemostasis and thrombosis using whole exome sequencing and functional/structural analyses of clot properties in patient samples. Our major interest is in disorders affecting fibrinogen, both quantitative and qualitative. With fibrin, produced by thrombin-mediated cleavage, fibrinogen plays important roles in many physiological processes. The formation of a stable blood clot, containing polymerized and cross-linked fibrin, is crucial to prevent blood loss and drive wound healing upon vascular injury. The fibrin clot structure, which can be influenced by a large number of variables, has been linked to cardiovascular disease risk.
We are looking for motivated candidates with qualifications in Biomedical Sciences or Biophysics interested in translating results obtained from basic medical science studies into a better knowledge of patient phenotypes towards personalised treatments. Experience in Bioinformatics or Statistics is a plus.
Two positions, one post-doctoral, one for a PhD student, are available immediately in the laboratory of Prof. Marguerite Neerman-Arbez (UNIGE) and Dr. Alessandro Casini (HUG). The Faculty of Medicine at the University of Geneva offers a stimulating and competitive scientific work environment with state of the art infrastructures and core facilities.
Contact and Address
Interested candidates should send their CV, letter of motivation and the contact details of three referees by email to Marguerite.Neerman-Arbezunige.ch or Alessandro.Casinihcuge.ch