Laboratory Technician Protein Purification (80-100%)

 
Published
Closing Date
WorkplaceVilligen, North West Switzerland, Switzerland
Category
Position
Occupation rate
80% - 100%
Job Start01.09.2021

The company

Founded in 2015, leadXpro AG is a lead compound discovery company focusing on membrane protein drug targets such as GPCRs, ion-channels and transporters for the discovery and optimization of next-generation medicines. Based on a unique platform for membrane protein expression, purification and engineering, the preferred access to synchrotron/free electron laser (SLS/SwissFEL) for X-ray analysis and cryo-EM facilities (Uni Basel), leadXpro is able to characterize the interaction of small molecules and biotherapeutics with drug targets timely to impact the drug discovery of novel therapeutics. The position at leadXpro is an excellent opportunity to join a young and exciting company engaged in cutting-edge applied research. leadXpro is located at PARK INNOVAARE, 5234 Villigen, Switzerland. For more information, please visit: ?url=http%3A%2F%2Fleadxpro.com&module=jobs&id=52024" target="_blank" rel="nofollow">http://leadxpro.com

Description

The position

leadXpro is urgently seeking a highly motivated and enthusiastic Laboratory Technician who will be part of an interdisciplinary team of scientists working on leadXpro proprietary and partnered projects, within a highly collaborative international environment. She/he will perform membrane protein purification and their biochemical characterization in quantities that enable structural and biophysical studies.

Key tasks and responsibilities

The successful candidate will be expected to work within a dynamic team that values transparency, integrity, reliability and a passion for science to create benefits for patients.

Key duties include:

  • Performing scientific research under guidance of an experienced supervisor
  • Small scale purification and optimization of purification processes (Detergents screen, buffer conditions, etc...) and proactively in troubleshoot purification challenges
  • Purification of membrane proteins using chromatography methods (affinity, ion exchange and size exclusion chromatography)
  • Good knowledge of Akta instrument handling
  • Monitoring of protein quality and purity using fluorescence-size exclusion chromatography and SDS-PAGE
  • Maintenance of laboratory records and participation in data analysis
  • Taking part in laboratory organization and maintenance of supplies and equipment

Requirements

Your qualifications

Applicants should preferably have an apprenticeship education or B.Sc. in biochemistry, molecular biology, biotechnology or a related discipline. Previous experience with membrane protein biochemistry would be an advantage as well as experience in biochemical/biophysical assays. Excellent communication skills and fluency in English is essential.

Contact and Address

How to apply

If you are interested to join the team, please send your complete application in English with the keyword “Laboratory Technician Protein Purification” in the subject line to: infoleadXpro.com

The deadline for the application is 10th of March, 2021.

Email

Web

In your application, please refer to myScience.ch and reference JobID 52024.