news from the lab 2015

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Medicine/Pharmacology



Results 1 - 20 of 27.

Medicine/Pharmacology - Life Sciences
21.12.2015
Eyes turn into skin: how inflammation can change the fate of cells
Eyes turn into skin: how inflammation can change the fate of cells
21.12.15 - EPFL scientists have found that chronic inflammation can cause regenerating cells to grow into new, aberrant types; this is called metaplasia, and is a disorder linked to prolonged inflammation. The study highlights a new concept of chronic inflammation and could lead to better treatments.
Life Sciences - Medicine/Pharmacology
18.12.2015
Architecture of mTOR protein complex solved
Architecture of mTOR protein complex solved
It has long been known that the protein TOR - Target of Rapamycin - controls cell growth and is involved in the development of diseases such as cancer and diabetes. Through a collaborative effort scientists from the ETH Zürich and from the Biozentrum of the University of Basel have now succeeded in revealing the unique architecture of the mammalian TOR complex 1 (mTORC1) in detail.
Medicine/Pharmacology - Life Sciences
15.12.2015
Treating colon cancer with vitamin A
Treating colon cancer with vitamin A
15.12.15 - Scientists at EPFL identify the biological pathway behind the growth of colon cancer, and block it with vitamin A. A leading cause of cancer deaths worldwide, colon cancer is famously resistant to treatment. There are many reasons for this, but one has to do with a group of persisting cancer cells in the colon that cause relapses.
Medicine/Pharmacology - Life Sciences
09.12.2015
Using
Using "big data" to fight flu
Thanks to "big data", researchers have identified new molecules that are instrumental in the replication of the flu virus. If these host proteins are blocked, influenza viruses are unable to multiply as effectively. The international study therefore makes a significant contribution towards the development of new treatments and flu drugs.
Life Sciences - Medicine/Pharmacology
09.12.2015
Out now: A microscope that sees live cells in 3D
Out now: A microscope that sees live cells in 3D
EPFL spin-off Nanolive has launched the 3D Cell Explorer, a microscope for observing living cells in 3D.
Medicine/Pharmacology - Life Sciences
01.12.2015
Genes for a longer, healthier life found
Genes for a longer, healthier life found
Out of a 'haystack' of 40,000 genes from three different organisms, scientists at ETH Zurich and a research consortium in Jena have found genes that are involved in physical ageing. If you influence only one of these genes, the healthy lifespan of laboratory animals is extended - and possibly that of humans, too.
Life Sciences - Medicine/Pharmacology
24.11.2015
Lactate for Brain Energy
Lactate for Brain Energy
Nerve cells cover their high energy demand with glucose and lactate. Scientists of the University of Zurich now provide new support for this. They show for the first time in the intact mouse brain evidence for an exchange of lactate between different brain cells. With this study they were able to confirm a 20-year old hypothesis.
Life Sciences - Medicine/Pharmacology
24.11.2015
Bacterial Nanomachine Serves as a Versatile Tool
Bacterial Nanomachine Serves as a Versatile Tool
The team from the startup company "T3 Pharmaceuticals" at the Biozentrum of the University of Basel has developed a fast and simple technique that can provide valuable insights into important life processes and which can be applied for therapeutic purposes. In the recent issue of the "Journal of Cell Biology", the young entrepreneurs describe a bacterial nanomachine that they implement as a tool to selectively inject diverse proteins into cells.
Medicine/Pharmacology - Physics/Materials Science
17.11.2015
3D-mapping a new drug-delivery tool
3D-mapping a new drug-delivery tool
17.11.15 - Scientists from EPFL and Nestlé have developed a new method that can "see" inside dispersed cubosomes (dispersed cubic liquid crystalline phases) with unprecedented detail. The breakthrough can help to improve their design significantly for better drug or nutrient delivery. Cubosomes are small biological "capsules" that can deliver molecules of nutrients or drugs with high efficiency.
Medicine/Pharmacology
13.11.2015
Gaming Against Heart Disease in Diabetic Patients
Gaming Against Heart Disease in Diabetic Patients
Exercise is healthy - this applies to all of us, especially though for people suffering from type 2 diabetes. Researchers from the University of Basel were able to show that fitness games, or "exergames", for the Nintendo Wii console are suitable to increase cardiorespiratory fitness in type 2 diabetic patients and thus lower the risk of related heart disease.
Medicine/Pharmacology - Environment/Sustainable Development
11.11.2015
Tackling a neglected disease with math
Tackling a neglected disease with math
11.11.15 - Schistosomiasis is a parasitic disease that is endemic in sub-Saharan Africa.
Life Sciences - Medicine/Pharmacology
06.11.2015
When less is really more
When less is really more
ETH researchers have found that therapeutic iron supplements may be less effective when given in brief intervals: A peptide molecule blocks iron absorption in the intestine even 24 hours after the iron administation. Anaemia is often the result of an iron deficiency. In such cases the patients, who are typically female, will be prescribed iron supplements to be taken daily.
Medicine/Pharmacology - Life Sciences
27.10.2015
Intestinal worms
Intestinal worms "talk" to gut bacteria to boost the immune system
27.10.15 - EPFL researchers have discovered how intestinal worm infections cross-talk with gut bacteria to help the immune system. Intestinal worms infect over 2 billion people across the world, mostly children, in areas with poor sanitation. But despite causing serious health problems, worms can actually help the immune system of its host as an indirect way of protecting themselves.
Medicine/Pharmacology - Physics/Materials Science
23.10.2015
Monitoring critical blood levels in real time in the ICU
Monitoring critical blood levels in real time in the ICU
23.10.15 - For patients in intensive care, knowing how much glucose, lactate and other substances are in the blood is a question of life or death. EPFL has developed a miniaturized microfluidic device that will allow medical staff to monitor these levels in real time and react more quickly.
Chemistry - Medicine/Pharmacology
23.10.2015
Potato harvest reduced by half
Potato harvest reduced by half
On the way from field to fork, more than half of the potato harvest is lost. This is according to a new study conducted by researchers from Agroscope and ETH Zurich.
Medicine/Pharmacology
15.10.2015
Fighting age-related health impairments with mind and body
Fighting age-related health impairments with mind and body
In promoting mental health, combined mental and physical training is more effective than physical training alone, as ETH human movement scientists have shown in a study of people over 70. Age-related health impairments affect not just the body but also the mind. Scientists refer to its mental symptoms as "mild cognitive impairment" (MCI): sufferers misplace things, can't recall the name of the neighbour they've just been talking to, or become generally less responsive.
Life Sciences - Medicine/Pharmacology
14.10.2015
Looking at the brain with a geologist's
Looking at the brain with a geologist's "eye"
14.10.15 - Using a geologist's imaging tool, researchers have made unprecedented high-resolution images of how carbon atoms from glucose are integrated into brain cells, providing new insight and opening new doors into the fate of glucose in the brain. Glucose - a form of sugar - fuels the brain.
Life Sciences - Medicine/Pharmacology
12.10.2015
Genetic variation is key to fighting viruses
Genetic variation is key to fighting viruses
12.10.15 - Using a genome-wide association study, EPFL scientists have identified subtle genetic changes that can cause substantial differences to how we fight viral infections. When infected with a virus, the response of our immune systems varies widely from person to person. This variation is of great concern, as these differences can determine clinical outcome as well as effectiveness of vaccinations.
Life Sciences - Medicine/Pharmacology
30.09.2015
Real-time analysis of metabolic products
Real-time analysis of metabolic products
Biologists at ETH Zurich have developed a method that, for the first time, makes it possible to measure concentration changes of several hundred metabolic products simultaneously and almost in real time. The technique could inspire basic biological research and the search for new pharmaceutical agents.
Life Sciences - Medicine/Pharmacology
10.08.2015
New details of the transmission of stimuli in living organisms unveiled
New details of the transmission of stimuli in living organisms unveiled
Researchers unveil new details about how cells in a living being process stimuli. The study focuses on so-called G-proteins, which help transmit external stimuli that reach a cell into its interior. Using a technique developed at the Paul Scherrer Institute PSI, the study authors discovered which parts of the G-proteins are vital for their functioning.

 
 
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