news from the lab 2015

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Pharmacology



Results 1 - 9 of 9.


Health - Pharmacology - 09.12.2015
Using
Using "big data" to fight flu
Thanks to "big data", researchers have identified new molecules that are instrumental in the replication of the flu virus. If these host proteins are blocked, influenza viruses are unable to multiply as effectively. The international study therefore makes a significant contribution towards the development of new treatments and flu drugs.

Life Sciences - Pharmacology - 24.11.2015
Lactate for Brain Energy
Lactate for Brain Energy
Nerve cells cover their high energy demand with glucose and lactate. Scientists of the University of Zurich now provide new support for this. They show for the first time in the intact mouse brain evidence for an exchange of lactate between different brain cells. With this study they were able to confirm a 20-year old hypothesis.

Pharmacology - Physics - 17.11.2015
3D-mapping a new drug-delivery tool
3D-mapping a new drug-delivery tool
17.11.15 - Scientists from EPFL and Nestlé have developed a new method that can "see" inside dispersed cubosomes (dispersed cubic liquid crystalline phases) with unprecedented detail. The breakthrough can help to improve their design significantly for better drug or nutrient delivery. Cubosomes are small biological "capsules" that can deliver molecules of nutrients or drugs with high efficiency.

Pharmacology - Health - 06.11.2015
When less is really more
When less is really more
ETH researchers have found that therapeutic iron supplements may be less effective when given in brief intervals: A peptide molecule blocks iron absorption in the intestine even 24 hours after the iron administation. Anaemia is often the result of an iron deficiency. In such cases the patients, who are typically female, will be prescribed iron supplements to be taken daily.

Life Sciences - Pharmacology - 30.09.2015
Real-time analysis of metabolic products
Real-time analysis of metabolic products
Biologists at ETH Zurich have developed a method that, for the first time, makes it possible to measure concentration changes of several hundred metabolic products simultaneously and almost in real time. The technique could inspire basic biological research and the search for new pharmaceutical agents.

Life Sciences - Pharmacology - 10.08.2015
New details of the transmission of stimuli in living organisms unveiled
New details of the transmission of stimuli in living organisms unveiled
Researchers unveil new details about how cells in a living being process stimuli. The study focuses on so-called G-proteins, which help transmit external stimuli that reach a cell into its interior. Using a technique developed at the Paul Scherrer Institute PSI, the study authors discovered which parts of the G-proteins are vital for their functioning.

Health - Pharmacology - 27.05.2015
Novartis presents new data on 21 medicines and 11 investigational compounds at ASCO and EHA
Overall survival data for Tafinlar and Mekinist combination to be presented in metastatic BRAF V600E/K mutation-positive cutaneous melanoma   New data for Zykadia in ALK+ non-small cell lung cancer (

Life Sciences - Pharmacology - 26.03.2015
How genes are permanently silenced by small RNAs
How genes are permanently silenced by small RNAs
Researchers have elucidated the mechanism underlying small RNA-mediated gene silencing, thus solving a mystery which has been puzzling the research community for over a decade. Back in 2002, the discovery by several research groups that small RNA molecules can shut down clearly defined genome regions was hailed by Science as the Breakthrough of the Year.

Life Sciences - Pharmacology - 13.03.2015
Antibiotics found to have unexpected effects on mitochondria
Antibiotics found to have unexpected effects on mitochondria
An EPFL study has shown that tetracycline-based antibiotics have an unexpected effect on the development of many organisms. In addition to pointing out the issue of soil pollution by these antibiotics, which are widely administrated to livestock, the scientists call upon colleagues to explore the consequences of using them in experiments that modulate gene expression.