news from the lab 2017

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Medicine/Pharmacology



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Life Sciences - Medicine/Pharmacology
27.12.2017
Bacteria acquire resistance from competitors
Bacteria acquire resistance from competitors
Bacteria not only develop resistance to antibiotics, they also can pick it up from their rivals. In a recent publication in "Cell Reports", Researchers from the Biozentrum of the University of Basel have demonstrated that some bacteria inject a toxic cocktail into their competitors causing cell lysis and death.
Medicine/Pharmacology - Computer Science/Telecom
26.12.2017
Looking back at 2017 (1/2)
Coral reefs that can survive global warming, an expedition around Antarctica, a booster for genetic research, a personnal virtual heart, a National Center for Data Science... Some of the EPFL's research and milestones that marked the year 2017.
Medicine/Pharmacology - Life Sciences
20.12.2017
Feasibility of Eliminating Rabies in Africa
Feasibility of Eliminating Rabies in Africa
The Swiss Tropical and Public Health Institute, together with European and African collaborators, carried out a mass dog vaccination in Chad and determined its effect on human rabies exposure. The study employed a bio-mathematical method for estimating the transmission dynamics of rabies. The researchers conclude that with political will and the necessary funding, elimination of rabies is possible in Africa.
Medicine/Pharmacology - Computer Science/Telecom
20.12.2017
New software can model natural light from the occupants' perspective
New software can model natural light from the occupants' perspective
OCUVIS, a visualization software developed by a soon-to-be-launched EPFL spin-off, lets architects simulate 3D building models to assess the performance of natural light indoors. After specifying the ambient conditions, architects can view the visual and non-visual characteristics of the resulting natural light in their designs.
Medicine/Pharmacology
20.12.2017
Feasibility of Eliminating Rabies in Africa
Feasibility of Eliminating Rabies in Africa
The Swiss Tropical and Public Health Institute, together with European and African collaborators, carried out a mass dog vaccination in Chad and determined its effect on human rabies exposure. The study employed a bio-mathematical method for estimating the transmission dynamics of rabies. The researchers conclude that with political will and the necessary funding, elimination of rabies is possible in Africa.
Physics/Materials Science - Medicine/Pharmacology
18.12.2017
Using gold nanoparticles to destroy viruses
Using gold nanoparticles to destroy viruses
EPFL researchers have created nanoparticles that attract viruses and, using the pressure resulting from the binding process, destroy them. This revolutionary approach could lead to the development of broad-spectrum antiviral drugs.  HIV, dengue, papillomavirus, herpes and Ebola - these are just some of the many viruses that kill millions of people every year, mostly children in developing countries.
Medicine/Pharmacology - Life Sciences
14.12.2017
The immune cells that help tumors instead of destroying them
The immune cells that help tumors instead of destroying them
EPFL scientists have discovered that neutrophils, a type of immune cell, can actually help lung tumors grow. The work is published in Cell Reports, and has enormous implications for cancer immunotherapy. Neutrophils inside lung adenocarcinoma tumors. On the left, neutrophils inside a mouse tumor are stained brown; on the right, neutrophils inside a human tumor are stained red (credit: E. Meylan/EPFL).
Life Sciences - Medicine/Pharmacology
13.12.2017
Protein Structure Could Unlock New Treatments for Cystic Fibrosis
Protein Structure Could Unlock New Treatments for Cystic Fibrosis
Cystic fibrosis is a severe hereditary disease of the lung, for which there is currently no cure. The underlying cause of the disease is a malfunction of the chloride channel CFTR, which prevents the secretion of chloride in certain body cells.
Life Sciences - Medicine/Pharmacology
13.12.2017
Cellular Self-Digestion Process Triggers Autoimmune Disease
Autophagy refers to a fundamental recycling process of cells that occurs in yeast, fungi, plants, as well as animals and humans. This process allows cells to degrade their own components and thus activate energy resources to be able to adapt to nutritional needs. In addition, autophagy plays a central role in steering an organism's immune response.
Medicine/Pharmacology - Life Sciences
11.12.2017
Novartis drug crizanlizumab shown to prolong time to patients’ first sickle cell pain crisis in subgroup analysis of SUSTAIN study
Investigational therapy crizanlizumab (SEG101, formerly SelG1) approximately doubled the time to first on-treatment sickle cell pain crisis, according to new subgroup analysis of Phase II SUSTAIN data Results were consistent across patient subgroups despite differences in disease severity, genotype or background therapy New findings for crizanlizumab, a potential disease-modifying, preventive treatment option for patients with sickle cell diseas
Medicine/Pharmacology - Life Sciences
11.12.2017
Liver Cancer: Lipid Synthesis Promotes Tumor Formation
Liver Cancer: Lipid Synthesis Promotes Tumor Formation
Lipid, also known as fat, is an optimal energy source and an important cell component. Much is required for the rapid and uncontrolled growth of cancer cells. Researchers from the Biozentrum of the University of Basel and from the University of Geneva have now discovered that the protein mTOR stimulates the production of lipids in liver tumors to satisfy the increased nutrient turnover and energy needs of cancer cells among other functions.
Medicine/Pharmacology - Physics/Materials Science
08.12.2017
Medicine/Pharmacology - Life Sciences
06.12.2017
Healthy mitochondria could stop Alzheimer's
Healthy mitochondria could stop Alzheimer's
Using a bioinformatics and experimental approach, scientists at EPFL have found that rendering mitochondria resistant to damage can halt diseases caused by amyloid toxicity, such as Alzheimer's disease. Alzheimer's disease is the most common form of dementia and neurodegeneration worldwide. A major hallmark of the disease is the accumulation of toxic plaques in the brain, formed by the abnormal aggregation of a protein called beta-amyloid inside neurons.
Life Sciences - Medicine/Pharmacology
01.12.2017
3D-printed minifactories
3D-printed minifactories
ETH researchers have developed a biocompatible ink for 3D printing using living bacteria. This makes it possible to produce biological materials capable of breaking down toxic substances or producing high-purity cellulose for biomedical applications. There will soon be nothing that cannot be produced with 3D printing.
Life Sciences - Medicine/Pharmacology
29.11.2017
A Big Data tool begins new era for biology and personalized medicine
A Big Data tool begins new era for biology and personalized medicine
Researchers from EPFL have developed a novel series of systems genetics tools to identify new links between genes and phenotypes. The work, a hallmark of EPFL's endeavors into the advancement of open science, brings biology to the cloud and sets the stage for the development of precision medicine. The study is published in Cell Systems.
Life Sciences - Medicine/Pharmacology
22.11.2017
Alzheimer's Tau protein forms toxic complexes with cell membranes
Alzheimer's disease is caused by tangles in the brain made up of malfunctioning aggregated Tau proteins. Scientists at EPFL have discovered a new toxic form of Tau that forms as a result of its interaction with cell membranes. The research is published and provides novel insights into possible mechanisms by which this protein moves in the brain and kills neurons.
Medicine/Pharmacology - Careers/Employment
21.11.2017
Dying in Switzerland: responding to the individual's every need
Dying in Switzerland: responding to the individual’s every need
Most people in Switzerland die in hospitals and nursing homes. Their specific needs are often not adequately met.
Medicine/Pharmacology - Life Sciences
21.11.2017
Pneumonia: Treatment with Vaccines instead of Antibiotics
Pneumonia: Treatment with Vaccines instead of Antibiotics
Mycoplasma bacteria are one of the most common causes of bacterial pneumonia in children. It is still unclear how the disease develops.
Medicine/Pharmacology - Agronomy/Food Science
20.11.2017
UZH Spearheads Largest European Study on Aging
UZH Spearheads Largest European Study on Aging
What began in 2012 is now entering its final stages: Europe's largest study on aging. The international research network behind the DO-HEALTH study is led by Heike Bischoff-Ferrari, Professor of Geriatric Medicine and Aging Research at the University of Zurich, and Head of the Department of Geriatrics at the UniversityHospital Zurich and the Waid City Hospital in Zurich, Switzerland.
Environment/Sustainable Development - Medicine/Pharmacology
14.11.2017
Global Warming - New Study Calls for Decisive Action
Global Warming - New Study Calls for Decisive Action
The largest global study to date on the effects of climate change on temperature-related mortality shows that more deaths due to hot weather may not be balanced by fewer deaths in colder world regions should global temperatures continue to rise. Swiss TPH, working for improved health of the people around the globe, prepared the data set for Switzerland.
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