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Health - Chemistry - 22.05.2019
Shedding light on cancer metabolism in real-time with bioluminescence
Shedding light on cancer metabolism in real-time with bioluminescence
Cancerous tumors can be made to bioluminesce, like fireflies, according to the level of their glucose uptake, giving rise to a technique for quantifying metabolite absorption. The firefly imaging technique for sugar can be translated from cancer to many other metabolic diseases. EPFL scientists have invented a new way to quantify - in real-time - glucose metabolism of cancerous tumors by making them bioluminesce.

Health - Social Sciences - 22.05.2019
Poor semen quality in Switzerland
Poor semen quality in Switzerland
Researchers at UNIGE have carried out the first nationwide study on semen quality of young Swiss men. And their verdict? Only 38% of men have semen parameter values above the norms set by World Health Organization for fertile men. Over the last fifty years, a marked decrease in sperm count has been observed in the Western World.

Health - Life Sciences - 21.05.2019
The insulin under the influence of light
The insulin under the influence of light
By understanding how day-night alternation affects the effect of insulin in tissues, researchers at UNIGE are highlighting the role of circadian rhythms in diabetes. The disruption of our internal clocks seems to play a significant role in the explosion of metabolic diseases observed in recent decades, and particularly of diabetes.

Pharmacology - Health - 21.05.2019
Using 3D to test personalised treatments in five days
Using 3D to test personalised treatments in five days
UNIGE researchers have developed a cell co-culture platform that can reproduce a patient's tumour in 3D and test the best treatment combinations for its specific case in just five days. Why doesn't the same treatment work in the same way for every patient? How can a drug's performance be optimised without causing side effects due to an excessive dosage? In an attempt to answer these questions, researchers at the University of Geneva (UNIGE), Switzerland, have devised a cell co-culture platform that reproduces a patient's tumour structure in 3D.

Health - Life Sciences - 20.05.2019
A new non-invasive therapy for people with paraplegia
A new non-invasive therapy for people with paraplegia
Researchers from the Alberto Santos Dumont Association for Research Support (AASDAP) in Brazil, in collaboration with EPFL, have developed a non-invasive strategy that combines functional electrostimulation and a brain-machine interface to help people with paraplegia walk again. This rehabilitation approach was tested on two patients, who showed an improvement in their motor skills and a partial neurological recovery.

Health - 17.05.2019
New Findings on Malaria Vaccine
New Findings on Malaria Vaccine
Protection by the malaria vaccine RTS,S is not only a matter of antibody quantity but also of quality. These are the findings of a study led by the Barcelona Institute for Global Health (ISGlobal) in collaboration with Swiss TPH and other partners. The research show for the first time that the higher the avidity of antibodies induced by the RTS,S vaccine, the greater the protection.

Health - Transport - 16.05.2019
Particles from aircraft engines affect airways
Particles from aircraft engines affect airways
In a unique experimental setup, Swiss researchers have investigated the effect of exhaust particles from aircraft turbine engines on human lung cells. The cells reacted most strongly to particles emitted during ground idling. The study also showed that the cytotoxic effect is only to some extent comparable to that of particles from gasoline and diesel engines.

Health - Environment - 15.05.2019
How your clothes influence the air you breathe
How your clothes influence the air you breathe
Researchers have taken a critical look at how much we really know about our exposure to particles and chemicals transported by our clothing. His study concludes that further research is needed and opens up new areas of investigation. There is growing evidence that our clothing exposes us to particles and chemicals on a daily basis - and that this exposure could carry significant health risks.

Life Sciences - Health - 14.05.2019
Relay station in the brain controls our movements
Relay station in the brain controls our movements
The relay station of the brain, the substantia nigra consists of different types of nerve cells and is responsible for controlling the execution of diverse movements. Researchers at the University of Basel's Biozentrum have now characterized two of these cell populations more precisely and has been able to assign an exact function to each of them.

Health - Environment - 13.05.2019
Daily doses of vitamin D are unreachable during Swiss winter
Daily doses of vitamin D are unreachable during Swiss winter
A study funded by the SNSF shows that in winter, weak sunlight prevents the Swiss population from producing sufficient levels of vitamin D. Too much sun increases the risk of skin cancer. But moderate exposure is required to produce vitamin D. This substance is essential for bone health and may also play a role in preventing respiratory infections, autoimmune diseases and certain types of cancer.

Health - Life Sciences - 09.05.2019
Cancer cells can communicate over longer distances within the body
Cancer cells can communicate over longer distances within the body
EPFL researchers have discovered that cancer cells use exosomes to communicate with each other and send information through the bloodstream. This breakthrough opens up new possibilities for the use of cancer immunotherapy techniques. "It was a huge surprise, we didn't expect to find so many melanoma cancer cell markers in blood exosomes," explains Hubert Girault, who heads up the Laboratory of Physical and Analytical Electrochemistry at EPFL Valais Wallis.

Health - Life Sciences - 06.05.2019
A barrier that keeps cancer at bay
A barrier that keeps cancer at bay
Scientists at EPFL have discovered a biological "barrier" that prevents cancer cells from forming new tumors and more importantly, from metastasizing. The study examines pancreatic neuroendocrine tumors and breast cancer. Activins are proteins involved in a number of important biological functions, including the regulation of the menstrual cycle, cell proliferation, differentiation, apoptosis, metabolism, homeostasis, immune response, wound repair, and endocrine function.

Life Sciences - Health - 02.05.2019
A model to decipher the complexity of gene regulation
A model to decipher the complexity of gene regulation
Scientist at the Universities of Geneva and Lausanne, Switzerland, designed a framework to analyse gene regulation, and offer a model to better understand the role of the non-coding portion of the genome in disease risk. More than genes themselves, how, where and when they are expressed determine our biological traits - our phenotypes.

Health - Psychology - 29.04.2019
Susceptibility to Disease Develops during Childhood
Traumatized children and children who develop multiple allergies tend to suffer in adulthood from chronic inflammatory diseases and psychiatric disorders. Researchers at the Universities of Zurich and Lausanne have demonstrated this in a study in which they identified five classes of early immune-system programming.

Health - Pharmacology - 26.04.2019
Individual nutrition shows benefits in hospital patients
Individual nutrition shows benefits in hospital patients
Individualized nutrition not only causes hospital patients to consume more protein and calories, but also improves clinical treatment outcomes. This has been demonstrated in a study by researchers from the University of Basel and Aarau Cantonal Hospital in the journal The Lancet. People who struggle to eat and drink properly following an illness are at risk of consuming too little protein and energy.

Life Sciences - Health - 25.04.2019
Intestinal organoid development mimics regeneration
Intestinal organoid development mimics regeneration
Intestinal organoids are three-dimensional structures derived from a single intestinal stem cell. They are great tools for applications ranging from fundamental biology to personalized and regenerative medicine. However, despite their relevance in research, it is still unclear how a single cell can give rise to a fully formed organoid.

Health - 25.04.2019
One in two Swiss people will have smoked weed by 2045
One in two Swiss people will have smoked weed by 2045
Three decades from now, nearly half of the Swiss population will have had some experience with cannabis use. According to a new study by the University of Zurich, the number of active users will rise as well, increasing by 50% compared to 2015 - unless the government establishes new regulations. Countries such as Canada and Uruguay have introduced new paradigms when it comes to regulating the sale and consumption of cannabis.

Health - Pharmacology - 23.04.2019
Simple and Fast Method for Radiolabelling Antibodies against Breast Cancer
Simple and Fast Method for Radiolabelling Antibodies against Breast Cancer
Radioactive antibodies that target cancer cells are used for medical diagnostics with PET imaging or for targeted radioimmunotherapy. Researchers from the University of Zurich have created a new method for radiolabelling antibodies using UV light. In less than 15 minutes, the proteins are ready-to-use for cancer imaging or therapy.

Health - Pharmacology - 15.04.2019
Precise Decoding of Breast Cancer Cells Creates New Option for Treatment
Researchers at the University of Zurich and from IBM Research have investigated the varying composition of cancer and immune cells in over one hundred breast tumors. They've found that aggressive tumors are often dominated by a single type of tumor cell. If certain immune cells are present as well, an immune therapy could be successful for a specific group of breast cancer patients.

Health - Pharmacology - 11.04.2019
The way people walk says a lot about how healthy they are
The way people walk says a lot about how healthy they are
Gait characteristics are sometimes regarded as the sixth vital sign in humans. They serve as a valuable indicator of a person's health, particularly in older adults - so why not measure them? A team of EPFL researchers is taking part in a major European project to design a device that can assess a person's gait more accurately.
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