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Pharmacology
Results 41 - 56 of 56.
Parkinson's disease: wearable sensors to track symptoms
Scientists have developed algorithms that, combined with wearable sensors, could help clinicians to monitor the progression of Parkinson's disease and assess the effects of medications commonly used by people with this neurodegenerative disorder. Parkinson's disease affects neurons in an area of the brain that controls movement, causing tremors, difficulty walking and other motor problems.
Scientists have developed algorithms that, combined with wearable sensors, could help clinicians to monitor the progression of Parkinson's disease and assess the effects of medications commonly used by people with this neurodegenerative disorder. Parkinson's disease affects neurons in an area of the brain that controls movement, causing tremors, difficulty walking and other motor problems.
Fighting dementia with play
Cognitive motor training helps in the fight against Alzheimer's and dementia, as demonstrated for the first time in a study by an international team of researchers with ETH Zurich involvement. The training platform used was developed by an ETH Zurich spin-off. A dementia diagnosis turns the world upside down, not only for the person affected but also for their relatives, as brain function gradually declines.
Cognitive motor training helps in the fight against Alzheimer's and dementia, as demonstrated for the first time in a study by an international team of researchers with ETH Zurich involvement. The training platform used was developed by an ETH Zurich spin-off. A dementia diagnosis turns the world upside down, not only for the person affected but also for their relatives, as brain function gradually declines.
Veal calf fattening: it can work with less antibiotics
By adopting a few simple measures, farmers can drastically reduce the use of antibiotics and improve the well-being of their animals without economic disadvantages. This was confirmed in a field trial- the first of its kind in Switzerland - carried out by researchers of the University of Bern based on the specially developed "outdoor veal calf" method.
By adopting a few simple measures, farmers can drastically reduce the use of antibiotics and improve the well-being of their animals without economic disadvantages. This was confirmed in a field trial- the first of its kind in Switzerland - carried out by researchers of the University of Bern based on the specially developed "outdoor veal calf" method.
Promising Treatment Alternative Against Parasitic Worm Infection
Strongyloidiasis, a parasitic worm infection caused by soil-transmitted helminths, remains a neglected public health problem with limited treatment options. Swiss TPH researchers conducted the first dose-finding study with moxidectin against strongyloidiasis. The drug could become a treatment alternative to the only treatment available so far and help fill the empty anthelminthic drug pipeline.
Strongyloidiasis, a parasitic worm infection caused by soil-transmitted helminths, remains a neglected public health problem with limited treatment options. Swiss TPH researchers conducted the first dose-finding study with moxidectin against strongyloidiasis. The drug could become a treatment alternative to the only treatment available so far and help fill the empty anthelminthic drug pipeline.
Retinal implants can give artificial vision to the blind
A team of EPFL engineers has developed technology that could partially restore vision in blind people. Being able to make blind people see again sounds like the stuff of miracles or even science fiction. And it has always been one of the biggest challenges for scientists. Diego Ghezzi, who holds the Medtronic Chair in Neuroengineering (LNE) at EPFL's School of Engineering, has made this issue a research focus.
A team of EPFL engineers has developed technology that could partially restore vision in blind people. Being able to make blind people see again sounds like the stuff of miracles or even science fiction. And it has always been one of the biggest challenges for scientists. Diego Ghezzi, who holds the Medtronic Chair in Neuroengineering (LNE) at EPFL's School of Engineering, has made this issue a research focus.
Predicting success in therapy with individualized cancer models
Scientists at Urology Research Laboratory of the Department for BioMedical Research (DBMR), University of Bern and Urology Department of the Inselspital of Bern, have established organoid culture models from prostate tumor biopsies. These are small clusters of cells which can be used to test the efficacy of various drugs.
Scientists at Urology Research Laboratory of the Department for BioMedical Research (DBMR), University of Bern and Urology Department of the Inselspital of Bern, have established organoid culture models from prostate tumor biopsies. These are small clusters of cells which can be used to test the efficacy of various drugs.
Controlling adhesions in the abdomen
Adhesions are scars in the abdomen, which can occur after surgery, often have serious consequences. Now, researchers from the University of Bern and Inselspital, University Hospital Bern, in collaboration with Canadian researchers, have discovered how such adhesions form. The findings may help to develop a drug to prevent adhesions in the future.
Adhesions are scars in the abdomen, which can occur after surgery, often have serious consequences. Now, researchers from the University of Bern and Inselspital, University Hospital Bern, in collaboration with Canadian researchers, have discovered how such adhesions form. The findings may help to develop a drug to prevent adhesions in the future.
Scientists model a peculiar type of breast cancer
Scientists led by EPFL have developed a breakthrough in vivo model for invasive lobular carcinoma, a serious yet understudied type of breast cancer. The work will open up previously inaccessible study of the tumor's biology and help discover new therapies. Invasive lobular carcinoma (ILC) is a type of breast cancer that begins in the milk-producing glands (lobules) of the breast.
Scientists led by EPFL have developed a breakthrough in vivo model for invasive lobular carcinoma, a serious yet understudied type of breast cancer. The work will open up previously inaccessible study of the tumor's biology and help discover new therapies. Invasive lobular carcinoma (ILC) is a type of breast cancer that begins in the milk-producing glands (lobules) of the breast.
Drug-checking services: effective approach to harm reduction
Drug-checking services with substance analyses help reduce the risks associated with drug use. A study commissioned by the FOPH shows that this service helps protect users from overdoses and adverse reactions to adulterants. The study also underlines the potential of drug checking for identifying vulnerable individuals at an early stage and for monitoring the drug market.
Drug-checking services with substance analyses help reduce the risks associated with drug use. A study commissioned by the FOPH shows that this service helps protect users from overdoses and adverse reactions to adulterants. The study also underlines the potential of drug checking for identifying vulnerable individuals at an early stage and for monitoring the drug market.
Hide-and-Seek Can Lead to Higher Drug Prices
Pharmaceutical manufacturers and national authorities often negotiate secret rebates when determining drug prices. A UZH study shows that these rebate systems may hamper patient access to drugs. In the medium term, this practice can even lead to increasing drug prices. In Switzerland and other European countries, drug prices are regulated to ensure affordable access to drugs.
Pharmaceutical manufacturers and national authorities often negotiate secret rebates when determining drug prices. A UZH study shows that these rebate systems may hamper patient access to drugs. In the medium term, this practice can even lead to increasing drug prices. In Switzerland and other European countries, drug prices are regulated to ensure affordable access to drugs.
Artificial aorta can reduce patients' blood pressure
Engineers at EPFL's Center for Artificial Muscles have developed a silicone aorta that can reduce how hard patients' hearts have to pump. Their breakthrough could offer a promising alternative to heart transplants. "Over 23 million people around the world suffer from heart failure. The disease is usually treated with a transplant, but because donated hearts are hard to come by, there is an ongoing need for alternative therapies.
Engineers at EPFL's Center for Artificial Muscles have developed a silicone aorta that can reduce how hard patients' hearts have to pump. Their breakthrough could offer a promising alternative to heart transplants. "Over 23 million people around the world suffer from heart failure. The disease is usually treated with a transplant, but because donated hearts are hard to come by, there is an ongoing need for alternative therapies.
3D-printed bioresorbable airway stent
An ETH Zurich research team is using 3D printing to produce a new type of bioresorbable airway stent. This could greatly simplify the future treatment of upper airway obstruction. Narrowing of the trachea or the main bronchi due to injury or illness can end very badly. If patients get too little oxygen, they risk suffocating and often need medical help as quickly as possible.
An ETH Zurich research team is using 3D printing to produce a new type of bioresorbable airway stent. This could greatly simplify the future treatment of upper airway obstruction. Narrowing of the trachea or the main bronchi due to injury or illness can end very badly. If patients get too little oxygen, they risk suffocating and often need medical help as quickly as possible.
Better poison dosages for better prostate cancer therapies
A given substance may be fundamental for life or may serve as a poison. All depends on the specific dose. At first glance, this somewhat paradoxical principle in medicine was first coined by the Swiss physician Paracelsus more than half a millennium ago when he stated: "All things are poison, and nothing is without poison.
A given substance may be fundamental for life or may serve as a poison. All depends on the specific dose. At first glance, this somewhat paradoxical principle in medicine was first coined by the Swiss physician Paracelsus more than half a millennium ago when he stated: "All things are poison, and nothing is without poison.
New treatment helps patients with a spinal cord injury
Spinal cord injuries disrupt the mechanism by which our bodies regulate blood pressure. A team of Swiss and Canadian scientists have developed a treatment that allows patients to regain control of their blood pressure, using targeted electrical spinal-cord stimulation. No medication is required. The team's findings were published today in Nature.
Spinal cord injuries disrupt the mechanism by which our bodies regulate blood pressure. A team of Swiss and Canadian scientists have developed a treatment that allows patients to regain control of their blood pressure, using targeted electrical spinal-cord stimulation. No medication is required. The team's findings were published today in Nature.
Detailed tumour profiling
As part of a clinical study involving patients from the University Hospitals in Zurich and Basel, researchers are conducting a thorough and highly precise investigation into the molecular and functional properties of tumours. Their goal is to help physicians to better determine which treatment will best match every patient's cancer and thus be most effective.
As part of a clinical study involving patients from the University Hospitals in Zurich and Basel, researchers are conducting a thorough and highly precise investigation into the molecular and functional properties of tumours. Their goal is to help physicians to better determine which treatment will best match every patient's cancer and thus be most effective.
Immune cells discovered in the lungs improve virus defense
A research team at the University of Basel has discovered immune cells resident in the lungs that persist long after a bout of flu. Experiments with mice have shown that these helper cells improve the immune response to reinfection by a different strain of the flu virus. The discovery could yield approaches to developing longer-lasting vaccinations against quickly-mutating viruses.
A research team at the University of Basel has discovered immune cells resident in the lungs that persist long after a bout of flu. Experiments with mice have shown that these helper cells improve the immune response to reinfection by a different strain of the flu virus. The discovery could yield approaches to developing longer-lasting vaccinations against quickly-mutating viruses.