(Image: Pixabay CC0)
Scientists from the UNIGE and LMU show that the anti-tumour activity of the immune system - and the effectiveness of cancer immunotherapies - depends on the time of day. . (Image: Pixabay CC0) - The ability of tumours to take hold and grow depends, among other things, on the effectiveness of the immune system in fighting them. Cancer cells, like pathogens, can be identified and targeted by a specific immune response. Building on this, immunotherapy treatments aim to strengthen the immune response to better fight the disease. In previous studies, the team from the University of Geneva and the Ludwig-Maximilians University of Munich (LMU) had shown that the activation of the immune system is modulated according to the time of day, indicating a peak of efficiency early in the morning in humans. Today, the research team demonstrates that the rhythmicity of the immune system - and in particular that of dendritic cells, its key sentinels - has a hitherto unsuspected impact on tumour growth, as well as on the effectiveness of immunotherapeutic treatments.
TO READ THIS ARTICLE, CREATE YOUR ACCOUNT
And extend your reading, free of charge and with no commitment.
