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Health - Pharmacology - 16.11.2022
How an Emerging Drug Class Dampens Harmful Immune Reactions
Although the complement system forms part of the innate immune system, it can cause damage to the body in some cases. This is because unwanted complement activation contributes to many autoimmune and chronic inflammatory diseases. Now, researchers have described molecular details of a recently approved class of drugs that can inhibit the complement system.

Life Sciences - Health - 16.11.2022
A chip to replace animal testing
A chip to replace animal testing
Researchers are developing a medical chip in collaboration with the ETH Zurich and the Cantonal Hospital of St.Gallen that will allow statements to be made about the effect of substances on babies in the womb. The Zurich-based ProCare Foundation is funding the project, which was recently launched.

Environment - Health - 15.11.2022
Monitoring antibiotic resistance in wastewater
Monitoring antibiotic resistance in wastewater
Researchers at Eawag recommend setting up a monitoring system for antibiotic resistance in the synthesis report of the National Research Programme NRP 72 Antimicrobial resistance, similar to the wastewater monitoring for Sars-CoV-2. Antibiotic resistance endangers human and animal health worldwide. In order to be able to introduce effective measures against antibiotic-resistant pathogens, it is important to have detailed knowledge of the current situation and how resistances are spreading in the environment.

Health - Pharmacology - 15.11.2022
Improving Diagnosis for Extrapulmonary Tuberculosis
Improving Diagnosis for Extrapulmonary Tuberculosis
Tuberculosis (TB) remains one of the world's biggest infectious disease killers. It is a complicated disease to diagnose and treat, even more so when it affects organs outside of the lung. A clinical trial in Tanzania tested a diagnostic algorithm including point-of-care ultrasound to increase the proportion of correctly managed patients.

Health - 14.11.2022
Foot insoles from the 3D printer
Foot insoles from the 3D printer
Two students from the School of Life Sciences FHNW have developed a new type of 3D printer in close collaboration with the orthopedic company Orthopodo Malgaroli. With this, Orthopodo can now print custom-fit orthopedic foot orthoses for its customers quickly, easily and in a resource-saving manner.

Health - Life Sciences - 14.11.2022
How Covid-19 Causes Neurological Damage
How Covid-19 Causes Neurological Damage
Although the coronavirus known as SARS-CoV-2 does not infect nerve cells, it can cause damage to the nervous system. Researchers from the University of Basel and University Hospital Basel have studied the mechanisms responsible for this effect, known as -neuro-Covid-, and identified starting points for its prevention.

Health - Physics - 11.11.2022
Researchers open door to stain-free labeling of cellular components
Researchers open door to stain-free labeling of cellular components
Scientists at EPFL and the Consiglio Nazionale delle Ricerche (CNR), the University Federico II, and CEINGE-Biotecnologie avanzate in Naples, Italy, have developed a new method to screen individual cells quickly and reliably without fluorescence labeling. Their work, published in the journal Nature Photonics, opens new avenues in early tumor diagnosis and drug development.

Health - Pharmacology - 09.11.2022
A new nanoparticle to act at the heart of cells
A new nanoparticle to act at the heart of cells
A team from the University of Geneva and LMU developed a transport nanoparticle to make an anti-inflammatory drug much more effective and less toxic. How can a drug be delivered exactly where it is needed, while limiting the risk of side effects? The use of nanoparticles to encapsulate a drug to protect it and the body until it reaches its point of action is being increasingly studied.

Life Sciences - Health - 09.11.2022
Scientists identify neurons that restore walking after paralysis
A new study by scientists at the.NeuroRestore research center has identified the type of neuron that is activated and remodeled by spinal cord stimulation, allowing patients to stand up, walk and rebuild their muscles - thus improving their quality of life. This discovery, made in nine patients, marks a fundamental, clinical breakthrough.

Health - Chemistry - 07.11.2022
Stable membrane for therapeutic carriers
Stable membrane for therapeutic carriers
Cells can generate vesicles as a response to changes in their environment. Although such cell-derived vesicles have great potential for biomedical research, their membrane is fragile and they have tendency to cluster together. Researchers at the University of Basel have successfully introduced a strategy to overcome these issues by equipping the vesicular membrane with a stabilizing shell.

Health - 07.11.2022
Sugar molecules as a target in cancer therapy
Sugar molecules as a target in cancer therapy
Cancer cells use sugar molecules on their surface to disable attacks by the body's immune system. Researchers at the University of Basel now report on how this mechanism can be neutralized. November 2022 The immune system is actually extremely well equipped to get rid of abnormal cells. As a safety mechanism, special features are built into healthy cells so that the immune system recognizes them, thus preventing a mistaken attack.

Health - Life Sciences - 04.11.2022
A new weapon against antibiotic-resistant bacteria
A new weapon against antibiotic-resistant bacteria
A team from the University of Geneva reveals that a drug used against herpes can fight a bacterium that is resistant to most antibiotics by weakening its defence mechanisms. The unreasonable use of antibiotics has pushed bacteria to develop resistance mechanisms to this type of treatment. This phenomenon, known as antibiotic resistance, is now considered by the WHO as one of the greatest threats to health.

Health - Life Sciences - 01.11.2022
Better understanding of the development of intestinal diseases
Bacteria in the small intestine adapt dynamically to our nutritional state, with individual species disappearing and reappearing. Researchers at the University of Bern and University Hospital Bern have now been able to comprehensively study the bacteria of the small intestine and their unique adaptability for the first time.

Health - Life Sciences - 01.11.2022
Getting Closer to Understanding Sudden Cardiac Death
The heart disease arrhythmogenic cardiomyopathy can lead to sudden death, particularly affecting young athletes. Researchers at the University of Basel have now genetically modified mice, which develop a similar disease to that found in humans. This allowed the team to identify previously unknown mechanisms and potential therapeutic targets.

Health - 01.11.2022
Detecting the antibodies responsible for thromboses and miscarriages
A team from the HUG, the UNIGE and Endotelix has developed a new test to detect antiphospholipids. This new test could detect antiphospholipid syndrome (APS), which causes clots that lead to thrombosis and disrupts pregnancy. Endotelix The Geneva University Hospitals (HUG), the University of Geneva and their spin-off Endotelix have created the best possible target molecule for the antibodies responsible for antiphospholipid syndrome.

Health - Social Sciences - 28.10.2022
Current Recommended Treatment against Whipworm Shows Better Results than New Drug Combination
Current Recommended Treatment against Whipworm Shows Better Results than New Drug Combination
Swiss TPH researchers tested two different drug combinations against the parasitic worm Trichuris trichiura on Pemba Island, Tanzania. Findings show that a new treatment combination (moxidectin and albendazole) is inferior compared to the current recommended treatment combination (ivermectin and albendazole).

Health - Innovation - 28.10.2022
A new device for early diagnosis of degenerative eye disorders
A new device for early diagnosis of degenerative eye disorders
Researchers at an EPFL lab have developed an ophthalmological device that can be used to diagnose some degenerative eye disorders long before the onset of the first symptoms. In early clinical trials, the prototype was shown to produce images with a sufficient degree of precision in just five seconds.

Pharmacology - Health - 27.10.2022
Vodka, Benzodiazepines & Co: A Dangerous Mix for Young People
At least 33 young people have died from polydrug use in Switzerland since 2018. Polydrug use refers to taking two or more psychoactive substances at the same time. The young adults are often unaware of the associated risks and rarely use the available services to minimize the risks, the initial results of a study by the Swiss Research Institute for Public Health and Addiction (IGSF) and the University of Zurich have shown.

Health - Life Sciences - 27.10.2022
The major chord that cures nightmares
The major chord that cures nightmares
A team from the UNIGE and the HUG has developed a promising method for treating people whose negative dreams are pathological. Oppressive, frightening, nerve-wracking: nightmares are particularly disturbing dreams. They are considered pathological when they occur frequently (>1 episode per week) and cause daytime fatigue, mood alteration and anxiety.

Health - Life Sciences - 26.10.2022
Fighting tumours with magnetic bacteria
Fighting tumours with magnetic bacteria
Researchers at ETH Zurich are planning to use magnetic bacteria to fight cancerous tumours. They have now found a way for these microorganisms to effectively cross blood vessel walls and subsequently colonise a tumour. Scientists around the world are researching how anti-cancer drugs can most efficiently reach the tumours they target.