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Health - Life Sciences - 03.08.2022 
First map of immune system connections reveals new therapeutic opportunities
Researchers of the Wellcome Sanger Institute and ETH Zurich have created the first full connectivity map of the human immune system, showing how immune cells communicate with each other and ways to modulate these pathways in disease. The immune system is made up of specialised cells, some of which individually travel through the body to scan for signs of injury or disease.
Health - Life Sciences - 02.08.2022 
Improved COVID-19 vector vaccine candidate
Scientists at the Institute of Virology and Immunology (IVI) and the University of Bern report on a Vesicular Stomatitis Virus (VSV)-vectored COVID-19 vaccine candidate. Their work shows that intramuscular immunization of mice with VSV-vectored COVID-19 vaccines is inducing strong antibody responses against the SARS-CoV-2 spike protein if the vector has been complemented with a specific protein.
Health - Campus - 28.07.2022 
Half of the population of Geneva have antibodies that neutralize the Omicron variants
A study by the HUG, the UNIGE and the EPFL shows that almost all Genevans (93.8%) have antibodies against SARS-CoV 2 but less than one in two (46.7%) have them against the BA.4/BA. Omicron sub-variants. A study by the Geneva University Hospitals (HUG), the Faculty of Medicine of the University of Geneva and the EPFL shows that almost all Genevans (93.8%) have antibodies against SARS-CoV 2, almost three quarters of whom acquired them through an infection.
Health - Earth Sciences - 26.07.2022 
Imaging the brain with ultrasound waves
As wave specialists, seismologists map the structure of planets from the information that seismic waves carry. Now, the team led by ETH professor Andreas Fichtner is also using this knowledge for medical imaging. Both ultrasound for medical imaging and seismology for imaging the Earth's interior measure the propagation of waves through matter.
Environment - Health - 20.07.2022 
One step closer to providing customized climate control in the office
Researchers have shown that people's perception of office temperature can vary considerably. Personalized climate control could therefore help enhance workers' comfort - and save energy at the same time. Global warming means that heatwaves are becoming ever-more frequent. At the same time, we're in a global race against the clock to reduce buildings' energy use and carbon footprint by 2050.
Health - Life Sciences - 18.07.2022 
Monitoring SARS-CoV-2 mutations thanks to wastewater sampling and bioinformatics
A study published today in Nature Microbiology highlights the great advantage of wastewater monitoring as being rapid, unbiased and cost-effective: the detection of genomic variants of SARS-CoV-2 in wastewater offers an early alert and can be based on fewer samples as compared to clinical samples. The bioinformatics tool developed by the groups of Niko Beerenwinkel and Tanja Stadler (ETH, Department of Biosystems Science and Engineering) in collaboration with Eawag and EPFL identifies variants of concern even at low abundance.
Health - Life Sciences - 15.07.2022 
Diabetes: a step closer to a life without insulin
A team from the University of Geneva reveals how the S100A9 protein improves metabolism of insulin-dependent diabetics by avoiding the deleterious effects of insulin. People with a severe form of diabetes, where the beta cells of the pancreas do not produce or no longer produce enough insulin, have no choice but to inject themselves regularly with artificial insulin in order to survive.
Health - Innovation - 14.07.2022 
The Right Environment for Fighting Cancer
Cancer immunotherapy is a successful form of treatment in oncology, but it doesn't work for every patient. One problem may be the lack of a specific type of immune cell in the tumor, researchers in the Department of Biomedicine at the University of Basel have found. The researchers were able to partially replace the cell's function using a signaling molecule.
Life Sciences - Health - 11.07.2022 
Also dogs develop malignant lymphoma
A study conducted by scientists at the Institute of Oncology Research (IOR, affiliated with USI and a member of Bios+) in collaboration with researchers specialized in veterinary oncology at the Universities of Turin and Bologna, identified the most frequent mutations in diffuse large B-cell lymphoma (DLBCL), one of the most frequent tumors in both humans and dogs, opening new therapeutic opportunities.
Health - Life Sciences - 08.07.2022 
Severe flu risk as immune cells swap with age
Researchers found that in mice, long-lived embryonic macrophages in the lungs die upon aging and during infection and are replaced by inflammatory bone marrow-derived macrophages. This causes severe disease progression when infected with viral flu. Lung infections with the influenza virus or a coronavirus more frequently result in severe disease progression in older people.
Life Sciences - Health - 07.07.2022 
Copper leads to protein aggregation
Copper exposure in the environment and the protein alpha-synuclein in the human brain could play an important role in the pathogenesis of Parkinson's disease. A team from Empa and the University of Limerick was able to show how the protein takes on an unusual shape when exposed to large amounts of copper ions.
Health - 06.07.2022
Life Sciences - Health - 06.07.2022
Health - Pharmacology - 05.07.2022 
How Omicron dodges the immune system
By comparing the neutralisation capacity induced by the different variants of SARS-CoV-2, a team from the UNIGE and the HUG reveals the exceptional capacity of Omicron to evade our immunity. The current wave of COVID-19 highlights a particularly high risk of reinfection by the Omicron variant of SARS-CoV-2.
Health - Psychology - 01.07.2022 
New Diagnosis for Post-Traumatic Stress Disorder
The World Health Organization (WHO) recently listed a new sibling diagnosis for post-traumatic stress disorder (PTSD), termed complex post-traumatic stress disorder (CPTSD). An international team with the involvement of the University of Zurich has now summarized the symptoms of the long-awaited new diagnosis and issued guidelines for clinical assessment and treatment.
Health - 30.06.2022 
The mere sight of a meal triggers an inflammatory response in the brain
Even before carbohydrates reach the bloodstream, the very sight and smell of a meal trigger the release of insulin. For the first time, researchers from the University of Basel and University Hospital Basel have shown that this insulin release depends on a short-term inflammatory response that takes place in these circumstances.
Health - Pharmacology - 27.06.2022 
Nitric Oxide Does Not Improve Babies’ Recovery after Heart Surgery
Infants undergoing heart surgery are connected to a heart-lung machine and given nitric oxide as an anti-inflammatory. Researchers from the Universities of Zurich and Queensland have now conducted the world's largest study of its kind, showing that using nitric oxide does not improve children's recovery after surgery.
Health - Life Sciences - 23.06.2022 
With a hydrogel against black skin cancer
Researchers at the University of Bern have developed a therapy option that activates the body's own defense system against black skin cancer. Components of a bacterium are embedded in gel and applied directly to the area of the tumor. In the model, the gel was shown to reduce tumor growth, inhibit its spread to other organs and thereby prolong survival.
Health - Innovation - 23.06.2022 
Wearable muscles
Researchers at ETH Zurich have developed a wearable textile exomuscle that serves as an extra layer of muscles. They aim to use it to increase the upper body strength and endurance of people with restricted mobility. Improved endurance thanks to the exomuscle The researchers have recently tested this prototype for the first time in a study featuring 12 participants: ten people without any physical impairments, one person with muscular dystrophy (Michael Hagmann) and one person with a spinal cord injury.
Health - 22.06.2022 
Breast cancer spreads at night
A new study shows that breast cancer metastases form more efficiently while patients are sleeping. This finding, in a study led by researchers at ETH Zur-ich, could significantly change the way cancer is diagnosed and treated in future. Breast cancer is one of the most common forms of cancer, according to the World Health Organization (WHO).
Health
Results 81 - 100 of 187.
Researchers of the Wellcome Sanger Institute and ETH Zurich have created the first full connectivity map of the human immune system, showing how immune cells communicate with each other and ways to modulate these pathways in disease. The immune system is made up of specialised cells, some of which individually travel through the body to scan for signs of injury or disease.
Scientists at the Institute of Virology and Immunology (IVI) and the University of Bern report on a Vesicular Stomatitis Virus (VSV)-vectored COVID-19 vaccine candidate. Their work shows that intramuscular immunization of mice with VSV-vectored COVID-19 vaccines is inducing strong antibody responses against the SARS-CoV-2 spike protein if the vector has been complemented with a specific protein.
A study by the HUG, the UNIGE and the EPFL shows that almost all Genevans (93.8%) have antibodies against SARS-CoV 2 but less than one in two (46.7%) have them against the BA.4/BA. Omicron sub-variants. A study by the Geneva University Hospitals (HUG), the Faculty of Medicine of the University of Geneva and the EPFL shows that almost all Genevans (93.8%) have antibodies against SARS-CoV 2, almost three quarters of whom acquired them through an infection.
As wave specialists, seismologists map the structure of planets from the information that seismic waves carry. Now, the team led by ETH professor Andreas Fichtner is also using this knowledge for medical imaging. Both ultrasound for medical imaging and seismology for imaging the Earth's interior measure the propagation of waves through matter.
Researchers have shown that people's perception of office temperature can vary considerably. Personalized climate control could therefore help enhance workers' comfort - and save energy at the same time. Global warming means that heatwaves are becoming ever-more frequent. At the same time, we're in a global race against the clock to reduce buildings' energy use and carbon footprint by 2050.
A study published today in Nature Microbiology highlights the great advantage of wastewater monitoring as being rapid, unbiased and cost-effective: the detection of genomic variants of SARS-CoV-2 in wastewater offers an early alert and can be based on fewer samples as compared to clinical samples. The bioinformatics tool developed by the groups of Niko Beerenwinkel and Tanja Stadler (ETH, Department of Biosystems Science and Engineering) in collaboration with Eawag and EPFL identifies variants of concern even at low abundance.
A team from the University of Geneva reveals how the S100A9 protein improves metabolism of insulin-dependent diabetics by avoiding the deleterious effects of insulin. People with a severe form of diabetes, where the beta cells of the pancreas do not produce or no longer produce enough insulin, have no choice but to inject themselves regularly with artificial insulin in order to survive.
Cancer immunotherapy is a successful form of treatment in oncology, but it doesn't work for every patient. One problem may be the lack of a specific type of immune cell in the tumor, researchers in the Department of Biomedicine at the University of Basel have found. The researchers were able to partially replace the cell's function using a signaling molecule.
A study conducted by scientists at the Institute of Oncology Research (IOR, affiliated with USI and a member of Bios+) in collaboration with researchers specialized in veterinary oncology at the Universities of Turin and Bologna, identified the most frequent mutations in diffuse large B-cell lymphoma (DLBCL), one of the most frequent tumors in both humans and dogs, opening new therapeutic opportunities.
Researchers found that in mice, long-lived embryonic macrophages in the lungs die upon aging and during infection and are replaced by inflammatory bone marrow-derived macrophages. This causes severe disease progression when infected with viral flu. Lung infections with the influenza virus or a coronavirus more frequently result in severe disease progression in older people.
Copper exposure in the environment and the protein alpha-synuclein in the human brain could play an important role in the pathogenesis of Parkinson's disease. A team from Empa and the University of Limerick was able to show how the protein takes on an unusual shape when exposed to large amounts of copper ions.
Gestures Can Improve Understanding in Language Disorders
When words fail, gestures can help to get the message across - especially for people who have a language disorder. An international research team has now shown that listeners attend the gestures of people with aphasia more often and for much longer than previously thought. This has implications for the use of gestures in speech therapy.
When words fail, gestures can help to get the message across - especially for people who have a language disorder. An international research team has now shown that listeners attend the gestures of people with aphasia more often and for much longer than previously thought. This has implications for the use of gestures in speech therapy.
Making CRISPR hype more of a reality
The latest CRISPR-based genome editing systems function more like molecular taxis rather than a pair of molecular scissors. This makes them much safer for patients who will soon benefit from gene therapies, as Eric Aird explains. This year we celebrate 10 years of genome editing with CRISPR. The system is often referred to as molecular scissors, and this designation is quite accurate for its first applications.
The latest CRISPR-based genome editing systems function more like molecular taxis rather than a pair of molecular scissors. This makes them much safer for patients who will soon benefit from gene therapies, as Eric Aird explains. This year we celebrate 10 years of genome editing with CRISPR. The system is often referred to as molecular scissors, and this designation is quite accurate for its first applications.
By comparing the neutralisation capacity induced by the different variants of SARS-CoV-2, a team from the UNIGE and the HUG reveals the exceptional capacity of Omicron to evade our immunity. The current wave of COVID-19 highlights a particularly high risk of reinfection by the Omicron variant of SARS-CoV-2.
The World Health Organization (WHO) recently listed a new sibling diagnosis for post-traumatic stress disorder (PTSD), termed complex post-traumatic stress disorder (CPTSD). An international team with the involvement of the University of Zurich has now summarized the symptoms of the long-awaited new diagnosis and issued guidelines for clinical assessment and treatment.
Even before carbohydrates reach the bloodstream, the very sight and smell of a meal trigger the release of insulin. For the first time, researchers from the University of Basel and University Hospital Basel have shown that this insulin release depends on a short-term inflammatory response that takes place in these circumstances.
Infants undergoing heart surgery are connected to a heart-lung machine and given nitric oxide as an anti-inflammatory. Researchers from the Universities of Zurich and Queensland have now conducted the world's largest study of its kind, showing that using nitric oxide does not improve children's recovery after surgery.
Researchers at the University of Bern have developed a therapy option that activates the body's own defense system against black skin cancer. Components of a bacterium are embedded in gel and applied directly to the area of the tumor. In the model, the gel was shown to reduce tumor growth, inhibit its spread to other organs and thereby prolong survival.
Researchers at ETH Zurich have developed a wearable textile exomuscle that serves as an extra layer of muscles. They aim to use it to increase the upper body strength and endurance of people with restricted mobility. Improved endurance thanks to the exomuscle The researchers have recently tested this prototype for the first time in a study featuring 12 participants: ten people without any physical impairments, one person with muscular dystrophy (Michael Hagmann) and one person with a spinal cord injury.
A new study shows that breast cancer metastases form more efficiently while patients are sleeping. This finding, in a study led by researchers at ETH Zur-ich, could significantly change the way cancer is diagnosed and treated in future. Breast cancer is one of the most common forms of cancer, according to the World Health Organization (WHO).
