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Life Sciences - Health - 29.09.2023 
A deep look into the progression of Parkinson's Disease
Scientists at EPFL use cutting-edge imaging techniques to shed light on the progression of Parkinson's disease by studying how the main culprit, the protein alpha-synuclein, disrupts cellular metabolism. Parkinson's disease is a complex neurodegenerative disorder that leads to the deterioration of specific types of neurons in the brain, resulting in a number of motor and non-motor symptoms.
Life Sciences - Health - 28.09.2023 
Parkinson’s: are our neurons more vulnerable at night?
A team from the University of Geneva shows that disruptions to the circadian clock increase the risk of developing a neurodegenerative disease. Disturbances in sleep patterns and the internal biological clock are frequently associated with Parkinson's disease. However, the link between biological rhythm and neuronal degeneration remains unclear.
Life Sciences - Health - 25.09.2023 
Marker for brain inflammation finally decoded
An international team co-led by UNIGE and HUG has decoded the only protein that can be used to ''see'' neuroinflammation. This discovery will improve the understanding of neurological and psychiatric disease mechanisms. Inflammation is the sign that our body is defending itself against an aggression.
Life Sciences - Health - 25.09.2023 
The dance of organ positioning: a tango of three proteins
Researchers uncover an intricate protein network controlling asymmetrical development of organs in the embryo, providing insights into genetic disorders and fundamental biology. In order to keep track of their environment, cells use cilia, antenna-like structures that can sense a variety of stimuli, including the flow of fluids outside the cell.
Health - Life Sciences - 22.09.2023
Life Sciences - Health - 20.09.2023 
Genetically modifying individual cells in animals
Researchers at ETH Zurich have developed a method that lets them genetically modify each cell differently in animals. This allows them to study in a single experiment what used to require many animal experiments. Using the new method, the researchers have discovered genes that are relevant for a severe rare genetic disorder.
Health - Pharmacology - 20.09.2023
Health - Pharmacology - 15.09.2023 
Understanding the ’’dance’’ of signalling proteins to stop inflammation
Inflammation is a normal response of our cells to fight stress, but too much of it can lead to a ''cytokine storm'' that can endanger life. A chain reaction of kinases activates the inflammatory response, like sequential switches. These enzymes have been heavily studied but little is known about their interactions, making it difficult to develop efficient drugs to target them.
Health - 13.09.2023 
Why some treatments lose their effectiveness
A recent study sheds light on why a proven treatment for lung cancer sometimes fails to work after a certain period of time. These new insights into changes in the immune system could make it possible to treat more patients with existing, highly effective drug therapies . Lung cancer is one of the leading causes of cancer-related death.
Health - Pharmacology - 12.09.2023 
Immunity to COVID-19 reduces contagiousness
A team from the University of Geneva and the HUG analysed the contacts of 50,000 COVID-19 positive cases. Immunity following vaccination provides better protection for those around you. Nearly one in three people exposed to SARS-CoV2 is infected, and as many as two in five with the Omicron variant. In the case of immunity — conferred by vaccination, infection or a combination of the two — this rate drops to one in ten.
Sport - Health - 12.09.2023 
Novel insights: How muscles change during endurance training
The more we exercise our endurance, the fitter we become - and so do our muscles. They adapt to the load and are able to perform better for a longer period of time. A research team at the University of Basel has now uncovered fresh insights into these muscle adaptations through experiments conducted on mice.
Life Sciences - Health - 07.09.2023 
The discovery of a new kind of cell revolutionizes neuroscience
A research team from the University of Lausanne and the Wyss Center has discovered a new type of cell essential to brain function. Hybrid in composition and function between the two hitherto known types of brain cells - neurons and glial cells - these cells of a new order are found in several brain regions from mice to humans.
Health - Life Sciences - 05.09.2023 
Reversing aging in the blood and immune systems
As we age, our bodies face many challenges, including declining immune system function and increased vulnerability to various health problems. A study conducted within the UNIL-CHUV Department of Oncology has recently shed light on these challenges. It unveils a potential solution that could have far-reaching implications for aging individuals.
Life Sciences - Health - 05.09.2023 
Deciphering the ’highway code’ of our cells
A team from the University of Geneva has identified a key mechanism in the regulation of microtubules, the internal communication pathways of our cells. Cancers, degenerative diseases: deregulation of our cells' internal communication pathways is at the root of many conditions. Microtubules - microscopic protein filaments - play a crucial role in controlling these exchanges.
Social Sciences - Health - 05.09.2023 
Active children are more resilient
The school year has hardly begun and the first exams are already approaching. According to findings by researchers from the University of Basel, school children cope better with the stress if they get plenty of daily exercise. "Get some exercise!" It's one suggestion adults frequently hear when they complain about stress in their lives.
Health - Life Sciences - 31.08.2023 
How fungal infections cause blood poisoning
Blood poisoning caused by a fungal infection is a severe, life-threatening condition. Researchers at the University of Bern have now discovered a mechanism that helps a yeast fungus to spread more easily within the body. The immune system, of all things, plays a major role in this process. These findings could open up new therapeutic avenues for blood poisoning caused by yeast, but also for other invasive fungal infections.
Health - Veterinary - 30.08.2023 
Scientists Apply Game Theory to End Rabies
Elimination of rabies in Africa could be within reach through a more coordinated One Health approach. An innovative study by Swiss TPH and partners applied game theory to tackle rabies challenges and identified effective strategies for affected countries. The paper, published in Nature Communications, demonstrates that a more coordinated approach could end this fatal disease and result in major health, economic and social gains.
Health - Life Sciences - 23.08.2023 
Cells with an ear for music release insulin
"We will rock you": researchers are developing a gene switch that triggers insulin release in designer cells by playing certain rock and pop songs. Diabetes is a condition in which the body produces too little or no insulin. Diabetics thus depend on an external supply of this hormone via injection or pump.
Health - 22.08.2023 
Cold air reduces croup symptoms in children
A study by UNIGE and HUG scientifically demonstrates that exposure to cold outside air is beneficial in reducing the symptoms of croup. For the first time, a scientific study shows that exposure to outdoor cold air is beneficial in reducing the severity of croup symptoms in children, particularly when symptoms are moderate.
Life Sciences - Health - 21.08.2023 
How Salmonella grow together in the gut and exchange antibiotic resistance
The ability to utilize a mere single alternative food source is all it takes for diarrhoea causing Salmonella bacteria to bloom when a gut is already colonized by a closely related strain, according to researchers from ETH Zurich. This coexistence enables the exchange of antibiotic resistance. Bacteria are growing more resistance to common antibiotics, and one key factor contributing to this problem is the exchange of antibiotic resistance genes between closely related bacterial strains.
Health
Results 1 - 20 of 131.
Scientists at EPFL use cutting-edge imaging techniques to shed light on the progression of Parkinson's disease by studying how the main culprit, the protein alpha-synuclein, disrupts cellular metabolism. Parkinson's disease is a complex neurodegenerative disorder that leads to the deterioration of specific types of neurons in the brain, resulting in a number of motor and non-motor symptoms.
A team from the University of Geneva shows that disruptions to the circadian clock increase the risk of developing a neurodegenerative disease. Disturbances in sleep patterns and the internal biological clock are frequently associated with Parkinson's disease. However, the link between biological rhythm and neuronal degeneration remains unclear.
An international team co-led by UNIGE and HUG has decoded the only protein that can be used to ''see'' neuroinflammation. This discovery will improve the understanding of neurological and psychiatric disease mechanisms. Inflammation is the sign that our body is defending itself against an aggression.
Researchers uncover an intricate protein network controlling asymmetrical development of organs in the embryo, providing insights into genetic disorders and fundamental biology. In order to keep track of their environment, cells use cilia, antenna-like structures that can sense a variety of stimuli, including the flow of fluids outside the cell.
Regeneration across complete spinal cord injuries reverses paralysis
A complete spinal cord injury leads to irreversible paralysis. Scientists at.NeuroRestore report in Science that they have developed a gene therapy that was proven in mice to stimulate nerve regrowth across such injuries and guide nerves to reconnect to their natural targets below the injuries in order to restore motor function.
A complete spinal cord injury leads to irreversible paralysis. Scientists at.NeuroRestore report in Science that they have developed a gene therapy that was proven in mice to stimulate nerve regrowth across such injuries and guide nerves to reconnect to their natural targets below the injuries in order to restore motor function.
Researchers at ETH Zurich have developed a method that lets them genetically modify each cell differently in animals. This allows them to study in a single experiment what used to require many animal experiments. Using the new method, the researchers have discovered genes that are relevant for a severe rare genetic disorder.
Strengthening artificial immune cells to fight cancer
Scientists in Western Switzerland have discovered how to improve the anti-tumour power of CAR-T cells, artificial immune ''super-cells'' used against blood cancers. Among available immunotherapies, the use of 'CAR-T' cells is proving extremely effective against certain blood cancers, but only in half of patients.
Scientists in Western Switzerland have discovered how to improve the anti-tumour power of CAR-T cells, artificial immune ''super-cells'' used against blood cancers. Among available immunotherapies, the use of 'CAR-T' cells is proving extremely effective against certain blood cancers, but only in half of patients.
Inflammation is a normal response of our cells to fight stress, but too much of it can lead to a ''cytokine storm'' that can endanger life. A chain reaction of kinases activates the inflammatory response, like sequential switches. These enzymes have been heavily studied but little is known about their interactions, making it difficult to develop efficient drugs to target them.
A recent study sheds light on why a proven treatment for lung cancer sometimes fails to work after a certain period of time. These new insights into changes in the immune system could make it possible to treat more patients with existing, highly effective drug therapies . Lung cancer is one of the leading causes of cancer-related death.
A team from the University of Geneva and the HUG analysed the contacts of 50,000 COVID-19 positive cases. Immunity following vaccination provides better protection for those around you. Nearly one in three people exposed to SARS-CoV2 is infected, and as many as two in five with the Omicron variant. In the case of immunity — conferred by vaccination, infection or a combination of the two — this rate drops to one in ten.
The more we exercise our endurance, the fitter we become - and so do our muscles. They adapt to the load and are able to perform better for a longer period of time. A research team at the University of Basel has now uncovered fresh insights into these muscle adaptations through experiments conducted on mice.
A research team from the University of Lausanne and the Wyss Center has discovered a new type of cell essential to brain function. Hybrid in composition and function between the two hitherto known types of brain cells - neurons and glial cells - these cells of a new order are found in several brain regions from mice to humans.
As we age, our bodies face many challenges, including declining immune system function and increased vulnerability to various health problems. A study conducted within the UNIL-CHUV Department of Oncology has recently shed light on these challenges. It unveils a potential solution that could have far-reaching implications for aging individuals.
A team from the University of Geneva has identified a key mechanism in the regulation of microtubules, the internal communication pathways of our cells. Cancers, degenerative diseases: deregulation of our cells' internal communication pathways is at the root of many conditions. Microtubules - microscopic protein filaments - play a crucial role in controlling these exchanges.
The school year has hardly begun and the first exams are already approaching. According to findings by researchers from the University of Basel, school children cope better with the stress if they get plenty of daily exercise. "Get some exercise!" It's one suggestion adults frequently hear when they complain about stress in their lives.
Blood poisoning caused by a fungal infection is a severe, life-threatening condition. Researchers at the University of Bern have now discovered a mechanism that helps a yeast fungus to spread more easily within the body. The immune system, of all things, plays a major role in this process. These findings could open up new therapeutic avenues for blood poisoning caused by yeast, but also for other invasive fungal infections.
Elimination of rabies in Africa could be within reach through a more coordinated One Health approach. An innovative study by Swiss TPH and partners applied game theory to tackle rabies challenges and identified effective strategies for affected countries. The paper, published in Nature Communications, demonstrates that a more coordinated approach could end this fatal disease and result in major health, economic and social gains.
"We will rock you": researchers are developing a gene switch that triggers insulin release in designer cells by playing certain rock and pop songs. Diabetes is a condition in which the body produces too little or no insulin. Diabetics thus depend on an external supply of this hormone via injection or pump.
A study by UNIGE and HUG scientifically demonstrates that exposure to cold outside air is beneficial in reducing the symptoms of croup. For the first time, a scientific study shows that exposure to outdoor cold air is beneficial in reducing the severity of croup symptoms in children, particularly when symptoms are moderate.
The ability to utilize a mere single alternative food source is all it takes for diarrhoea causing Salmonella bacteria to bloom when a gut is already colonized by a closely related strain, according to researchers from ETH Zurich. This coexistence enables the exchange of antibiotic resistance. Bacteria are growing more resistance to common antibiotics, and one key factor contributing to this problem is the exchange of antibiotic resistance genes between closely related bacterial strains.
