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Health - Pharmacology - 24.11.2022
Protein shapes indicate Parkinson’s disease
Researchers have found that a set of proteins have different shapes in the spinal fluid of healthy individuals and Parkinson's patients. These could be used in the future as a new type of biomarker for this disease. Many human diseases can be detected and diagnosed using biomarkers in blood or other body fluids.

Health - Life Sciences - 22.11.2022
Covid-19: the Spike protein is no longer the only target
Covid-19: the Spike protein is no longer the only target
A research team reveals a hidden cavity on a key SARS-CoV-2 protein to which drugs could bind. With the continuous emergence of new variants and the risk of new strains of the virus, the development of innovative therapies against SARS-CoV-2 remains a major public health challenge. Currently, the proteins that are on the surface of the virus and/or are involved in its replication are the preferred therapeutic targets, like the Spike protein targeted by vaccines.

Health - Life Sciences - 22.11.2022
Scientists unlock nature's secret to super-selective binding
Scientists unlock nature's secret to super-selective binding
Researchers have discovered that it is not just molecular density, but also pattern and structural rigidity, that control super-selective binding interactions between nanomaterials and protein surfaces. The breakthrough could help optimize existing approaches to virus prevention and cancer detection.

Health - Computer Science - 21.11.2022
Steerable soft robots could enhance medical applications
Steerable soft robots could enhance medical applications
Borrowing from methods used to produce optical fibers, researchers from EPFL and Imperial College have created fiber-based soft robots with advanced motion control that integrate other functionalities, such as electric and optical sensing and targeted delivery of fluids. Over the past decades, catheter-based surgery has transformed medicine, giving doctors a minimally invasive way to do anything from placing stents and targeting tumors to extracting tissue samples and delivering contrast agents for medical imaging.

Health - Chemistry - 21.11.2022
Liver cancer: How liver cells go astray
Liver cancer is one of the most deadly types of cancer. A team of University of Basel researchers has now uncovered how a healthy liver cell turns into a tumor cell. Comprehensive metabolic changes convert mature liver cells into immature progenitor cells. These cells proliferate rapidly and tumors develop.

Health - Innovation - 18.11.2022
Watching the metabolism at work
Watching the metabolism at work
Researchers from ETH Zurich and the University of Zurich are taking magnetic resonance imaging a step further. With their new method, they can visualise metabolic processes in the body. Their objective is to improve the future diagnosis and treatment of heart disease. Magnetic resonance imaging (MRI) has become an indispensable part of medicine.

Health - Life Sciences - 18.11.2022
The protein behind immunotherapy resistance
The protein behind immunotherapy resistance
Scientists at EPFL, Ludwig Institute of Cancer Research, and CHUV have identified a key protein that helps tumors evade attacks by the immune system, contributing to poor responses to immunotherapy in the clinic. Immunotherapy is a cutting-edge approach to treating cancer by turning the patient's own immune system against their tumor.

Health - Pharmacology - 16.11.2022
How an Emerging Drug Class Dampens Harmful Immune Reactions
Although the complement system forms part of the innate immune system, it can cause damage to the body in some cases. This is because unwanted complement activation contributes to many autoimmune and chronic inflammatory diseases. Now, researchers have described molecular details of a recently approved class of drugs that can inhibit the complement system.

Life Sciences - Health - 16.11.2022
A chip to replace animal testing
A chip to replace animal testing
Researchers are developing a medical chip in collaboration with the ETH Zurich and the Cantonal Hospital of St.Gallen that will allow statements to be made about the effect of substances on babies in the womb. The Zurich-based ProCare Foundation is funding the project, which was recently launched.

Environment - Health - 15.11.2022
Monitoring antibiotic resistance in wastewater
Monitoring antibiotic resistance in wastewater
Researchers at Eawag recommend setting up a monitoring system for antibiotic resistance in the synthesis report of the National Research Programme NRP 72 Antimicrobial resistance, similar to the wastewater monitoring for Sars-CoV-2. Antibiotic resistance endangers human and animal health worldwide. In order to be able to introduce effective measures against antibiotic-resistant pathogens, it is important to have detailed knowledge of the current situation and how resistances are spreading in the environment.

Health - Pharmacology - 15.11.2022
Improving Diagnosis for Extrapulmonary Tuberculosis
Improving Diagnosis for Extrapulmonary Tuberculosis
Tuberculosis (TB) remains one of the world's biggest infectious disease killers. It is a complicated disease to diagnose and treat, even more so when it affects organs outside of the lung. A clinical trial in Tanzania tested a diagnostic algorithm including point-of-care ultrasound to increase the proportion of correctly managed patients.

Health - 14.11.2022
Foot insoles from the 3D printer
Foot insoles from the 3D printer
Two students from the School of Life Sciences FHNW have developed a new type of 3D printer in close collaboration with the orthopedic company Orthopodo Malgaroli. With this, Orthopodo can now print custom-fit orthopedic foot orthoses for its customers quickly, easily and in a resource-saving manner.

Health - Life Sciences - 14.11.2022
How Covid-19 Causes Neurological Damage
How Covid-19 Causes Neurological Damage
Although the coronavirus known as SARS-CoV-2 does not infect nerve cells, it can cause damage to the nervous system. Researchers from the University of Basel and University Hospital Basel have studied the mechanisms responsible for this effect, known as -neuro-Covid-, and identified starting points for its prevention.

Health - Physics - 11.11.2022
Researchers open door to stain-free labeling of cellular components
Researchers open door to stain-free labeling of cellular components
Scientists at EPFL and the Consiglio Nazionale delle Ricerche (CNR), the University Federico II, and CEINGE-Biotecnologie avanzate in Naples, Italy, have developed a new method to screen individual cells quickly and reliably without fluorescence labeling. Their work, published in the journal Nature Photonics, opens new avenues in early tumor diagnosis and drug development.

Health - Pharmacology - 09.11.2022
A new nanoparticle to act at the heart of cells
A new nanoparticle to act at the heart of cells
A team from the University of Geneva and LMU developed a transport nanoparticle to make an anti-inflammatory drug much more effective and less toxic. How can a drug be delivered exactly where it is needed, while limiting the risk of side effects? The use of nanoparticles to encapsulate a drug to protect it and the body until it reaches its point of action is being increasingly studied.

Life Sciences - Health - 09.11.2022
Scientists identify neurons that restore walking after paralysis
A new study by scientists at the.NeuroRestore research center has identified the type of neuron that is activated and remodeled by spinal cord stimulation, allowing patients to stand up, walk and rebuild their muscles - thus improving their quality of life. This discovery, made in nine patients, marks a fundamental, clinical breakthrough.

Health - Chemistry - 07.11.2022
Stable membrane for therapeutic carriers
Stable membrane for therapeutic carriers
Cells can generate vesicles as a response to changes in their environment. Although such cell-derived vesicles have great potential for biomedical research, their membrane is fragile and they have tendency to cluster together. Researchers at the University of Basel have successfully introduced a strategy to overcome these issues by equipping the vesicular membrane with a stabilizing shell.

Health - 07.11.2022
Sugar molecules as a target in cancer therapy
Sugar molecules as a target in cancer therapy
Cancer cells use sugar molecules on their surface to disable attacks by the body's immune system. Researchers at the University of Basel now report on how this mechanism can be neutralized. November 2022 The immune system is actually extremely well equipped to get rid of abnormal cells. As a safety mechanism, special features are built into healthy cells so that the immune system recognizes them, thus preventing a mistaken attack.

Health - Life Sciences - 04.11.2022
A new weapon against antibiotic-resistant bacteria
A new weapon against antibiotic-resistant bacteria
A team from the University of Geneva reveals that a drug used against herpes can fight a bacterium that is resistant to most antibiotics by weakening its defence mechanisms. The unreasonable use of antibiotics has pushed bacteria to develop resistance mechanisms to this type of treatment. This phenomenon, known as antibiotic resistance, is now considered by the WHO as one of the greatest threats to health.

Health - Life Sciences - 01.11.2022
Better understanding of the development of intestinal diseases
Bacteria in the small intestine adapt dynamically to our nutritional state, with individual species disappearing and reappearing. Researchers at the University of Bern and University Hospital Bern have now been able to comprehensively study the bacteria of the small intestine and their unique adaptability for the first time.
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