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In a new study, scientists have uncovered the complex genetic and environmental interactions influencing metabolic health and have validated their findings in actual human data. Metabolic syndrome (MetS) is a health condition characterized by a group of risk factors: high blood pressure, high blood sugar, unhealthy cholesterol levels, and abdominal fat.

Scientists at the University of Geneva have identified the genetic sequences that regulate the activity of the genes responsible for bone growth. In mammals, only 3% of the genome consists of coding genes which, when transcribed into proteins, ensure the biological functions of the organism and the in-utero development of future individuals.

Researchers at ETH Zurich have developed a cell-based bone model to help investigate the cause of this genetic condition. For someone suffering from brittle bone disease, life is fraught with complications. The slightest misstep, a seemingly harmless fall or even one false move can be all'it takes to leave them with a broken arm or leg.

In a recently launched project, the aquatic research institute Eawag is investigating how the use of borehole thermal energy storage (BTES) affects the surrounding soil, the groundwater and the microorganisms living in it. In collaboration with Empa and its Demonstrator Energy Hub (ehub), a project is being developed in a unique setting on the campus in Dübendorf.

Do our brains process natural voices and deepfake voices differently? Research conducted at the University of Zurich indicates that this is the case. In a new study, researchers have identified two brain regions that respond differently to natural and deepfake voices. Much like fingerprints, our voices are unique and can help us identify people.

Researchers at EPFL have discovered how networks of neurons in fruit flies transform simple brain signals into coordinated actions. This sheds light on the neural mechanisms underlying complex behaviors for potential application in robotics. Understanding how animals, including humans, transform brain signals into coordinated movements is a fundamental question in neuroscience.

How do pathogens invade the lungs? Using human lung microtissues, a team at the Biozentrum of the University of Basel has uncovered the strategy used by a dangerous pathogen. The bacterium targets specific lung cells and has developed a sophisticated strategy to break through the lungs' line of defense.

Researchers at UZH have found that the maturation of the senses for smell and touch is closely linked in mice and that this strong interaction takes place within a narrow developmental time window. These findings not only underline the importance of environmental stimuli for brain assembly in early life, but also the interdependent development of the senses.

The annual killifish lives in regions with extreme drought. A research group at the University of Basel now reports in "Science" that the early embryogenesis of killifish diverges from that of other species. Unlike other fish, their body structure is not predetermined from the outset. This could enable the species to survive dry periods unscathed.

A recent study carried out at the University of Lausanne reveals that both excess and deficiency of the same protein can lead to severe intellectual impairment. The discovery opens up vital prospects for the early diagnosis of a rare developmental disorder. A team of scientists led by Alexandre Reymond, an expert in human genetics at the Centre intégratif de génomique (CIG) and Professor at the Faculty of Biology and Medicine (FBM) at the University of Lausanne (UNIL), has produced a major breakthrough in the detection of a rare genetic disease.

Scientists from the University of Geneva have discovered how to increase the lifespan of stem cells injected into cartilage to facilitate the regeneration of tissue damaged by osteoarthritis. Osteoarthritis, a degenerative disease of the cartilage that affects the majority of the elderly population, seriously compromises patients' quality of life.

A new study by scientists shows that age-related decline in motor ability can be countered in fruit flies by enhancing the expression of the protein Trio, suggesting potential treatments for age-related movement decline. As we age, we suffer a noticeable decline in motor ability, which affects our quality of life and independence.

Every year, researchers upload vast amounts of genetic information to publicly accessible databases.

Extensive social networks between different hunter-gatherer groups in the Congo Basin existed long before agriculture arrived in the region. This continent-wide exchange preserved a cultural diversity that evolved thousands of years ago, as researchers from the University of Zurich show based on musical instruments, specialized vocabulary and genetic information.

By exploring the effects of sport on memory, scientists from the University of Geneva have discovered compensatory mechanisms in the brains of young individuals at genetic risk of developing Alzheimer's disease. The benefits of physical activity on health are widely accepted, and those on cognitive capacity are increasingly well known.

Scientists, in collaboration with researchers at EMBL Heidelberg, have discovered that a group of marine protists (eukaryotic organisms) closely related to animals use open or closed mitosis based on their life cycle stages, suggesting that the way animal cells perform cell division evolved long before animals themselves.

Scientists from the University of Geneva have discovered that fentanyl leads to the activation of two distinct cell populations in the brain, first when the drug is taken and then during withdrawal, suggesting a novel model for opioid addiction. Fentanyl is a particularly powerful synthetic opioid. Diverted from its original medical use, it has become a deadly drug responsible for three-quarters of overdose deaths in the United States.

When cells become tumor cells, their metabolism changes fundamentally. Researchers at the University of Basel and the University Hospital Basel have now demonstrated that this change leaves traces that could provide targets for cancer immunotherapies. Cancer cells function in turbo mode: Their metabolism is programmed for rapid proliferation, whereby their genetic material is also constantly copied and translated into proteins.

A new statistical approach published in the journal PNAS reveals a major advance in the measurement of inbreeding. Under the direction of Jérôme Goudet, professor at the University of Lausanne and group leader at the SIB, the authors have developed a promising method for studying endangered species.

In EPFL's GenoRobotics project, a cross-disciplinary team of students is developing a novel method for identifying plant DNA - one that's faster, cheaper and less energy-intensive than the conventional one. The team hopes their new protocol, designed for use out in the field, will make it easier to categorize plants and ultimately help protect biodiversity.