Pharmacology - Aug 16
FDA approves Roche’s RozlytrekTM (entrectinib) for people with ROS1- positive, metastatic non- small cell lung cancer and NTRK gene fusion- positive solid tumours
FDA approves Roche’s RozlytrekTM (entrectinib) for people with ROS1- positive, metastatic non- small cell lung cancer and NTRK gene fusion- positive solid tumours
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On World Malaria Day 2019, Swiss organizations look back on a long history of successful public-private collaboration for new malaria medicines.
Roche launches new VENTANA HER2 Dual ISH companion diagnostic test for breast and gastric cancer patients eligible for targeted therapy
Nearly 2.1 million new cases of breast cancer are diagnosed worldwide each year, and more than 620,000 people will die from the disease.
Nearly 2.1 million new cases of breast cancer are diagnosed worldwide each year, and more than 620,000 people will die from the disease.
Physics enthusiasts will descend on Switzerland for this year's tournament, as the School defends the gold medal it won in 2018 - this time on its home turf.
Jamie Paik, the head of EPFL's Reconfigurable Robotics Lab, will present her reconfigurable robots at the TED2019 conference in Vancouver on 18 April.
In such a highly competitive environment as scientific research, it is a good idea to ask yourself on a regular basis just how well you fare by international comparison. With this in mind, Empa conducted a peer review last October: eleven international experts from all of Empa's areas of activity scrutinized the institute's output in research and innovation and compared it with the rest of the world.
AveXis data reinforce effectiveness of Zolgensma in treating spinal muscular atrophy (SMA) Type 1
Ph 3 STR1VE data show prolonged event-free survival, early and rapid increases in CHOP-INTEND and significant milestone achievement in SMA Type 1, consistent with START trial First-in-human biodist
Ph 3 STR1VE data show prolonged event-free survival, early and rapid increases in CHOP-INTEND and significant milestone achievement in SMA Type 1, consistent with START trial First-in-human biodist
Novartis announces FDA filing acceptance and Priority Review of brolucizumab (RTH258) for patients with wet AMD
By 2020, over 1.5 million people in the US are likely to have wet AMD, the leading cause of blindness in industrialized countries Filing is based on Phase III data from the HAWK and HARRIER
By 2020, over 1.5 million people in the US are likely to have wet AMD, the leading cause of blindness in industrialized countries Filing is based on Phase III data from the HAWK and HARRIER
"If we don’t seize this opportunity, others surely will"
Empa CEO Gian-Luca Bona on the opportunities and risks of digitalization - and the question as to how a materials research institute needs to gear itself up for this future.
Empa CEO Gian-Luca Bona on the opportunities and risks of digitalization - and the question as to how a materials research institute needs to gear itself up for this future.
Win-win for home and grid
Solar systems on the roofs of residential buildings often produce energy precisely when the tenants can't actually use it. Stationary batteries enable this energy to be utilized in the evening, at night or on a rainy day. A research project at Empa is investigating whether the use of stationary batteries makes economic sense for the consumer while at the same time offering advantages for energy suppliers.
Solar systems on the roofs of residential buildings often produce energy precisely when the tenants can't actually use it. Stationary batteries enable this energy to be utilized in the evening, at night or on a rainy day. A research project at Empa is investigating whether the use of stationary batteries makes economic sense for the consumer while at the same time offering advantages for energy suppliers.
Innovative Medicines Initiative Launches Translational Safety Biomarker Pipeline Project
The University of Zurich coordinates a worldwide research project that focuses on the development of new biomarkers.
The University of Zurich coordinates a worldwide research project that focuses on the development of new biomarkers.
Cooling with the sun
Can you cool with waste heat? Sure. A Swiss research project involving Empa, which ended in November, demonstrated this in an impressive way.
Can you cool with waste heat? Sure. A Swiss research project involving Empa, which ended in November, demonstrated this in an impressive way.
Computational power in the fight against cancer
Vittorio Limongelli, Associate professor at the USI Faculty of Biomedical Sciences and at the USI Institute of Computational Science (ICS), has recently received a competitive research funding consis
Vittorio Limongelli, Associate professor at the USI Faculty of Biomedical Sciences and at the USI Institute of Computational Science (ICS), has recently received a competitive research funding consis
ETH Zurich publishes investigation report
A number of recent media reports on the request for dismissal of an ETH astronomy professor have included quotes from internal and confidential documents relating to the ongoing proceedings. Given the growing public interest, as well as the need to ensure transparency and fairness, ETH Zurich has decided to publish anonymised versions of the final report of the administrative investigation and the recommendation of the special committee.
A number of recent media reports on the request for dismissal of an ETH astronomy professor have included quotes from internal and confidential documents relating to the ongoing proceedings. Given the growing public interest, as well as the need to ensure transparency and fairness, ETH Zurich has decided to publish anonymised versions of the final report of the administrative investigation and the recommendation of the special committee.
Tech4Impact, founded in 2017, is EPFL's pioneering multi-stakeholder platform where students, researchers, large enterprises, NGOs and startups come together to enhance the university's social and environmental impact in the areas of education, research and innovation.
Showy Primates Have Smaller Testicles
Well-adorned or well-endowed ' but not both. Evolutionary biologists at the University of Zurich have for the first time demonstrated that male primates either have large testicles or showy ornaments. Developing both at the same time may simply take too much energy. Male primates are highly competitive, especially about one thing: fathering offspring.
Well-adorned or well-endowed ' but not both. Evolutionary biologists at the University of Zurich have for the first time demonstrated that male primates either have large testicles or showy ornaments. Developing both at the same time may simply take too much energy. Male primates are highly competitive, especially about one thing: fathering offspring.
Animal-assisted therapy can foster social competence in patients with brain injuries and increase their emotional involvement during therapy. These were the findings of a clinical trial conducted by psychologists from the University of Basel and published in the journal Scientific Reports. After a severe traumatic brain injury, patients often exhibit problems in their social behavior.
Interview with new group leader Guillaume Diss
Guillaume Diss joined the FMI as a new Quantitative Biology group leader on March 1. His research focuses on understanding the mechanisms whereby genetic variation translates into phenotypic variation - for example, in diseases.
Guillaume Diss joined the FMI as a new Quantitative Biology group leader on March 1. His research focuses on understanding the mechanisms whereby genetic variation translates into phenotypic variation - for example, in diseases.
Engineers working on the CleanSpace One project at EPFL's Space Center have come up with a way of capturing and destroying the space debris that has built up over 60 years of low-orbit activities. That team has now founded a startup, ClearSpace, to further develop and market the technology. Since 2012, engineers at EPFL's Space Center have been hard at work on a new junk-clearing satellite to capture debris orbiting the earth.
Fondation Botnar has awarded CHF 7 million to researchers from Lausanne for further deployment of electronic diagnostic and treatment tools based on algorithms, which will help clinicians to manage febrile children.
Three researchers at the University of Zurich have received an ERC Advanced Grant. A physicist, a mathematician and a theologian will each receive up to 2.5 million euros from the European Research Council to continue their research.
ETH researchers with new ERC Grants
In its latest awarding process for the ERC Advanced Grants, the European Research Council (ERC) has selected five projects being conducted by ETH Zurich researchers.
In its latest awarding process for the ERC Advanced Grants, the European Research Council (ERC) has selected five projects being conducted by ETH Zurich researchers.
Roche and Spark Therapeutics, Inc. announce withdrawal and refiling of Premerger Notification and Report Form under the HSR Act and extension of tender offer for shares of Spark Therapeutics, Inc
Roche and Spark Therapeutics, Inc. (NASDAQ: ONCE) (“Spark”) today announced that Roche has withdrawn its Premerger Notification and Report Form under the Hart-Scott-Rodino Act (the “HSR Act”) in connection with Roche's pending acquisition of Spark.
Roche and Spark Therapeutics, Inc. (NASDAQ: ONCE) (“Spark”) today announced that Roche has withdrawn its Premerger Notification and Report Form under the Hart-Scott-Rodino Act (the “HSR Act”) in connection with Roche's pending acquisition of Spark.
Novartis first-in-class Cosentyx approved in China for psoriasis patients
China Health Authority NMPA approved Cosentyx (secukinumab) for moderate-to-severe plaque psoriasis in adult patients who are candidates for systemic therapy or phototherapy Cosentyx is the first b
China Health Authority NMPA approved Cosentyx (secukinumab) for moderate-to-severe plaque psoriasis in adult patients who are candidates for systemic therapy or phototherapy Cosentyx is the first b
AveXis expands world-leading gene therapy manufacturing capacity with purchase of advanced biologics therapy manufacturing campus in Longmont, Colorado
Facility to become the largest of four state-of-the-art sites involved in manufacturing of AveXis gene therapies for pipeline of rare genetic diseases including spinal muscular atrophy AveXis plans
Facility to become the largest of four state-of-the-art sites involved in manufacturing of AveXis gene therapies for pipeline of rare genetic diseases including spinal muscular atrophy AveXis plans
Professors Pierre Gönczy and Douglas Hanahan (School of Life Sciences), and Professor Tobias J. Kippenberg (School of Basic Sciences/School of Engineering) have been awarded ERC Advanced Grants.
Roche’s ipatasertib in combination with Tecentriq and chemotherapy shows promising anti-tumour activity in triple-negative breast cancer in early phase trial
Data from Phase Ib study to be presented at American Association for Cancer Research (AACR) 2019 annual congress 73% overall response rate (ORR) irrespective of PD-L1 status or PI3KCA/AKT1/PTEN alter
Data from Phase Ib study to be presented at American Association for Cancer Research (AACR) 2019 annual congress 73% overall response rate (ORR) irrespective of PD-L1 status or PI3KCA/AKT1/PTEN alter
The agricultural technics of wild hay making in Switzerland and shifting cultivation in the eastern Himalayas have one thing in common: They are both performed on steep slopes.
Examining the highly organized lives of long-distance commuters
When both parents face lengthy commutes to work, how do families handle the additional stress' An EPFL scientist took an in-depth look at the strategies these parents use for managing their time wisely and dealing with unexpected challenges. "Most studies on long-distance commuters focus on high-ranking executives who live and work in different countries.
When both parents face lengthy commutes to work, how do families handle the additional stress' An EPFL scientist took an in-depth look at the strategies these parents use for managing their time wisely and dealing with unexpected challenges. "Most studies on long-distance commuters focus on high-ranking executives who live and work in different countries.
Novartis receives FDA approval for Mayzent (siponimod), the first oral drug to treat secondary progressive MS with active disease
Mayzent (siponimod) is the first and only treatment specifically approved for patients with active secondary progressive multiple sclerosis (SPMS) in over 15 years Up to 80% of patients with relaps
Mayzent (siponimod) is the first and only treatment specifically approved for patients with active secondary progressive multiple sclerosis (SPMS) in over 15 years Up to 80% of patients with relaps
Diesel vans are dirtier in winter than many know: Where there are still gaps in emissions legislation, soot particles and nitrogen oxides (NOx) continue to be produced.
Corinne Boss Takes Reins of ’Animals and Products of Animal Origin’ Competence Division at Agroscope
Corinne Boss is the new Head of Agroscope's 'Animals and Products of Animal Origin' Competence Division for Research Technology and Knowledge Transfer; in this capacity, she also becomes a Member of the Agroscope Executive Board. A biologist and official expert in animal health, Corinne Boss currently works at the Swiss Federal Office for Agriculture (FOAG) as a Research Scientist in the 'Products of Animal Origin and Livestock Breeding' Division.
Corinne Boss is the new Head of Agroscope's 'Animals and Products of Animal Origin' Competence Division for Research Technology and Knowledge Transfer; in this capacity, she also becomes a Member of the Agroscope Executive Board. A biologist and official expert in animal health, Corinne Boss currently works at the Swiss Federal Office for Agriculture (FOAG) as a Research Scientist in the 'Products of Animal Origin and Livestock Breeding' Division.
"No one may be left behind," writes Unesco in its World Water Report. Today, three out of ten people have no access to safe drinking water and even less to sanitation facilities, often because they are discriminated against for various reasons.
Official comment on recent media coverage
ETH Zurich provides an official comment on articles published recently in the online magazine Republik.
ETH Zurich provides an official comment on articles published recently in the online magazine Republik.
Pharmacology - Aug 16
FDA approves Roche’s RozlytrekTM (entrectinib) for people with ROS1- positive, metastatic non- small cell lung cancer and NTRK gene fusion- positive solid tumours
FDA approves Roche’s RozlytrekTM (entrectinib) for people with ROS1- positive, metastatic non- small cell lung cancer and NTRK gene fusion- positive solid tumours