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Health - Life Sciences - 06.03.2021
Animal experiments still play a key role
Without animal experiments there would be no COVID-19 vaccine: animal testing is essential for medical research. A ban on testing - even a gradual phase-out - would be extremely damaging for research policy, writes Detlef Günther. The Swiss National Council is currently debating the popular initiative for a ban on experiments on animals and humans.

Health - Life Sciences - 03.03.2021
How to track the variants of the pandemic faster
How to track the variants of the pandemic faster
A global group of researchers is calling for better integration of viral genetics, bioinformatics, and public health to enable better pandemic response now and better pandemic preparedness in the future.

Life Sciences - 03.03.2021

Life Sciences - Health - 25.02.2021
Wyss Center joins $36M international collaboration to improve recovery from spinal cord injuries
Geneva, Switzerland - The Wyss Center has joined forces with an international consortium of universities, biomedical startups and nonprofit organizations to develop therapies for spinal cord injury that could improve long-term recovery.

Life Sciences - 16.02.2021
Of multiple-horned goats and sheep
Of multiple-horned goats and sheep
Scientists from the INRAE, ALLICE and UNIGE have discovered the genetic causes of the abnormal presence of an additional pair of horns in Bovids. Bovidae sometimes display supernumerary horns. For instance, local breeds of sheep genetically selected by generations of breeders, are known for their multiple horns, a condition referred to as 'polyceraty'.

Life Sciences - 16.02.2021
Extensive remodeling of chromatin after DNA damage
In eukaryotes, histones are often modified and evicted at site of DNA double-strand breaks in order to facilitate end-resection and break repair. Together with the protein analysis facility of the FMI, the Gasser group has quantified massive changes in the chromatin associated proteome in response to DNA damage.

Social Sciences - Life Sciences - 10.02.2021
Friends Matter: Giraffes that Group with Others Live Longer
Friends Matter: Giraffes that Group with Others Live Longer
Adult female giraffes who spend time in larger groups with other females live longer than less sociable individuals. The effects of sociability on survival outweigh other factors such as environment or human presence, a study of giraffes in Tanzania led by the University of Zurich has shown. A research team led by Monica Bond, research associate at the Department of Evolutionary Biology and Environmental Studies of the University of Zurich (UZH), studied giraffes in Tanzania for five years.

Life Sciences - Campus - 08.02.2021

Health - Life Sciences - 01.02.2021
A key regulator for humoral immunity and B lymphoma
A key regulator for humoral immunity and B lymphoma
The generation of antibodies in B-cells takes place in a dynamic structure that forms during infections, the germinal center (GC).

Environment - Life Sciences - 14.01.2021
Making organic waste management sustainable
Making organic waste management sustainable
Black soldier fly larvae (BSFL) treatment of organic waste offers a sustainable and economic solution to the need for organic waste management in Indonesia.

Life Sciences - Health - 11.01.2021
4D-Simulator breakthrough in brain surgery
4D-Simulator breakthrough in brain surgery
Aneurysm operations in the brain rank among the most delicate procedures in neurosurgery.

Life Sciences - Pharmacology - 18.12.2020
A weather station for epileptic seizure
A weather station for epileptic seizure
The unpredictability of epileptic seizures is a severe handicap for patients.

Life Sciences - Health - 18.12.2020
What immune cells reveal about sleep disorders
What immune cells reveal about sleep disorders
Daniela Latorre wanted to be a scientist since she was a child. At the Institute for Research in Biomedicine, affiliated to the USI in Bellinzona and the Institute of Microbiology, she is finding evidence that narcolepsy is an autoimmune disease. She has now received the Pfizer Prize for Research 2020 for her pioneering work.

Health - Life Sciences - 16.12.2020

Life Sciences - Environment - 11.12.2020

Career - Life Sciences - 07.12.2020

Life Sciences - 03.12.2020
Natural Selection also Increases the Adaptability of Organism
Natural selection causes organisms to adapt continuously. Researchers at the University of Zurich now show for the first time that proteins in bacteria develop a new property more rapidly when the selection pressure is high. Natural selection can thus also increase the evolutionary capacity itself.

Life Sciences - Environment - 25.11.2020
Wheat Diversity Due to Cross-Hybridization with Wild Grasses
Wheat Diversity Due to Cross-Hybridization with Wild Grasses
Bread wheat can grow in highly diverse regional environments. An important reason for its great genetic variety is the cross-hybridization with many chromosome fragments from wild grasses. This is shown by the genome sequences of 10 wheat varieties from four continents, which an international consortium including researchers from the University of Zurich has now decoded.

Life Sciences - Environment - 12.11.2020
Two lakes, seven whitefish species
Two lakes, seven whitefish species
In the journal ZooKeys, a group of scientists from Eawag and Bern University have described seven whitefish species endemic to the Bernese Oberland lakes - including four not previously described scientifically, two of which have only been identified as distinct species in the last few years.

Materials Science - Life Sciences - 06.11.2020
New light on cellular hydration
New light on cellular hydration
Researchers from EPFL's Institute of Bioengineering and the University of Geneva have teamed up to develop new tools for studying water flow across cell membranes.

Health - Life Sciences - 05.11.2020

Life Sciences - Health - 05.11.2020
A new generation of optogenetic tools for research and medicine
A new generation of optogenetic tools for research and medicine
The European Research Council (ERC) is providing 10 million euros in funding for an interdisciplinary, collaborative project in the structural and biophysical analysis of selected photoreceptors and t

Health - Life Sciences - 04.11.2020

Health - Life Sciences - 03.11.2020
Significant vulnerability in prostate cancer detected
Significant vulnerability in prostate cancer detected
Researchers at the University of Bern led an international team that has identified a novel vulnerability in advanced prostate cancer that is no longer responding to hormonal therapy. These findings could lead to the development of new treatment approaches for men suffering from the most aggressive form of prostate cancer.

Life Sciences - Computer Science - 02.11.2020
Building artificial neural networks inspired by the brain
Building artificial neural networks inspired by the brain
The requirements of real biological neural networks are modest compared to the complex deep neural networks used in machine learning, which come with substantial memory and energy demands. The Zenke group have developed a new method in machine learning called Neural Tangent Transfer to make a sparse neural network which performs almost as well as densely connected deep neural network on various learning tasks, but at a heavily reduced computing cost.

Life Sciences - 21.10.2020
How the visual cortex combines movement and vision
How the visual cortex combines movement and vision
The Keller group had previously shown that the coupling of sensory and motor experience was critical for normal sensorimotor processing. The researchers have now identified the particular subset of cortical neurons responsible for computing mismatches between what we expect to see based on movement and what we actually see, and are likely essential for helping us distinguish between self-generated and externally generated sensations.

Life Sciences - 15.10.2020

Health - Life Sciences - 29.09.2020
MarrowQuant: a new digital-pathology tool
MarrowQuant: a new digital-pathology tool
Scientists have developed a digital pathology tool for quantifying bone marrow compartments in standard histological sections. Named "MarrowQuant", the software makes it possible to examine bone marrow biopsies as well as to re-examine historical collections of bone-marrow samples and even old clinical trials.

Life Sciences - Environment - 29.09.2020
Wildcats threatened by their domestic cousins
Wildcats threatened by their domestic cousins
Wildcats in the Swiss Jura will undergo an irreversible genetic replacement by domestic cats if no preventive measures are taken. European wildcats, thought to be extinct 50 or so years ago in the Jura mountains, have since recolonised part of their former territory. This resurgence in an area occupied by domestic cats has gone hand-in-hand with genetic crosses between the two species.

Health - Life Sciences - 29.09.2020
MarrowQuant: a digital-pathology tool
MarrowQuant: a digital-pathology tool
Scientists have developed a digital pathology workflow for quantifying bone marrow compartments in standard histological sections. Named "MarrowQuant", this workflow based on the open source software QuPath makes it possible to examine bone marrow biopsies as well as to re-examine historical collections of bone-marrow samples and even old clinical trials.

Physics - Life Sciences - 25.09.2020

Life Sciences - Chemistry - 21.09.2020

Life Sciences - Chemistry - 21.09.2020
How to make a replication origin in multicellular eukaryotes
How to make a replication origin in multicellular eukaryotes
Loading of replicative helicases onto DNA is a key event during the initiation of chromosomal DNA replication.

Life Sciences - Health - 15.09.2020
Catalyst Fund selects six projects in its 2020 funding round
The Catalyst Fund - supported by the Bertarelli Foundation - has selected six research projects to fund this year. Led by professors from EPFL and other Swiss Universities, these projects all aim to develop new treatment options for neurological disorders. Created by the Bertarelli Foundation in 2017, the Catalyst Fund aims to invest in translational projects targeting innovative approaches for diseases affecting the brain, spinal cord, peripheral nervous system and sensory organs.

Environment - Life Sciences - 11.09.2020
The cold memory of the earth
The cold memory of the earth
On September 14, an expedition within the framework of the international project Ice Memory is setting out to carry out ice core drilling on the glacier of the mountain massif Grand Combin in the Swiss canton of Valais.

Health - Life Sciences - 08.09.2020
LifeTime - Researchers partner to improve European healthcare
LifeTime - Researchers partner to improve European healthcare
The FMI is a partner of the pan-European LifeTime initiative. In two publications, researchers involved with the initiative - including FMI group leader Susan Gasser - present a detailed roadmap of how to leverage the latest scientific breakthroughs and technologies over the next decade, to track, understand and treat human cells throughout an individual's lifetime.

Life Sciences - Health - 07.09.2020
How to identify new molecular glue degraders
How to identify new molecular glue degraders
Molecular glue degraders are a new class of drugs that work by facilitating an interaction between a disease-causing target protein and a ubiquitin ligase complex, tagging the target protein for degradation.

Life Sciences - Research Management - 03.09.2020

Life Sciences - Chemistry - 31.08.2020
FMI is a partner in the new EU “HCA|Organoid? project
FMI is a partner in the new EU “HCA|Organoid” project
Organoid? was launched today. It aims at validating organoids as faithful models of human biology, combining single-cell profiling and organoid technology.

Life Sciences - 25.08.2020

Health - Life Sciences - 24.08.2020
Breast cancer: New way for tumor cells to escape self-destruction
Breast cancer: New way for tumor cells to escape self-destruction
In the body, so-called programmed cell death prevents cells with irreparable damage from surviving and turning into cancer cells. In the "EMBO Journal", researchers at the University of Basel's Biozentrum, report how a certain protein variant thwarts the self-destruction and thus promotes the growth of breast cancer cells.

Life Sciences - 21.08.2020
The trick of proteins that
The trick of proteins that "slice" the DNA to recombine it
When our DNA breaks, cells use the so-called homologous recombination pathway to accurately repair the break, so that DNA is fixed and no mutations are introduced during the repair process. When multiple DNA molecules are broken, the recombination factors use a smart strategy to join only the DNA pieces originating from the same DNA molecules.

Health - Life Sciences - 18.08.2020
UZH Introduces Five New University Research Priority Programs
The University of Zurich is introducing five new University Research Priority Programs focusing on equal opportunities, human reproduction, rare diseases, digital religions and basic principles of learning.

Physics - Life Sciences - 14.08.2020
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