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Medicine/Pharmacology - Life Sciences
12.04.2018
Five proposals win initial
Five proposals win initial "catalyst" funding
Researchers from Campus Biotech were invited to develop joint projects with partner research institutes and bid for funding from the Bertarelli Foundation.
Life Sciences - Administration/Government
10.04.2018
Researcher Granted EUR 2.5 Million in Funding
Each year the European Research Council (ERC), open to both junior and established researchers, awards substantial funding for outstanding fundamental research.
Medicine/Pharmacology - Life Sciences
04.04.2018
Enhanced therapeutic vaccine platform achieves two proof of concepts in veterinary medical use
Enhanced therapeutic vaccine platform achieves two proof of concepts in veterinary medical use
Chronical allergic diseases of dogs and horses can now be treated with an innovative vaccine. It was developed by an international research team led by he University of Bern and in cooperation with the University of Zurich, together with private enterprise companies. The findings obtained in horses and dogs could lead to similar herapeutic vaccines for humans.
Medicine/Pharmacology - Life Sciences
04.04.2018
Therapeutic vaccine platform achieves proof of concepts in veterinary medical use
Scientists from the Universities of Bern, Zurich and Oxford as well as the Latvian Biomedical Research & Study Centre led by Prof. Martin F. Bachmann (University Clinic of Rheumatology, Immunoloy and Allergology, University of Bern) have developed a new therapeutic vaccine technology based upon enhanced virus like nanoparticle conjugates.
Medicine/Pharmacology - Life Sciences
23.03.2018
Medicine/Pharmacology - Life Sciences
23.03.2018
Phase III data in The Lancet show Novartis siponimod significantly improves outcomes in patients with secondary progressive MS
EXPAND shows oral siponimod (BAF312) is the first potential therapy to meaningfully delay disability progression in typical secondary progressive MS (SPMS) patients   Results demonstrate siponimod al
Medicine/Pharmacology - Life Sciences
22.03.2018
Novartis drug Tasigna approved by FDA to treat children with rare form of leukemia
Tasigna (nilotinib) approved for pediatric patients with newly diagnosed Ph+ CML-CP and children with Ph+ CML-CP resistant or intolerant to prior TKI therapy   New indication approved under FDA Prior
Medicine/Pharmacology - Life Sciences
21.03.2018
New Anti-Cancer Protein
New Anti-Cancer Protein
An international team of researchers has discovered a new anti-cancer protein. The protein, called LHPP, prevents the uncontrolled proliferation of cancer cells in the liver.
Medicine/Pharmacology - Life Sciences
20.03.2018
Phase III IMpower131 study showed Roche’s TECENTRIQ (atezolizumab) plus chemotherapy (carboplatin and Abraxane) reduced the risk of disease worsening or death in the initial treatment of people with a type of advanced squamous lung cancer
Phase III IMpower131 study showed Roche's TECENTRIQ (atezolizumab) plus chemotherapy (carboplatin and Abraxane) reduced the risk of disease worsening or death in the initial treatment of people with
Life Sciences - Medicine/Pharmacology
19.03.2018
Paraplegic rats walk again after therapy, now we know why
Paraplegic rats walk again in response to neuroprosthetic rehabilitation that allows the brain to elaborate new routes so that motor commands about walking, swimming and even climbing staircases reach spinal cord execution centers below the injury. With the help of robot-assisted rehabilitation and electrochemical spinal cord stimulation, rats with clinically-relevant spinal cord injury regain control of their otherwise paralyzed limbs.
Life Sciences
15.03.2018
Which Predators Make a Meal of Drosophila suzukii?
Which Predators Make a Meal of Drosophila suzukii?
Zurich-Reckenholz, 15.03.2018 - In search of native natural enemies of the exotic spotted-wing drosophila, Agroscope experts have developed a method for detecting its genetic material in the stomachs of predators. The spotted-wing drosophila (SWD or Drosophila suzukii ) is an introduced vinegar fly species that causes serious damage in Swiss crops.
Agronomy/Food Science - Life Sciences
14.03.2018
Agroscope Celebrates 10th Anniversary of Global Seed Vault
Agroscope Celebrates 10th Anniversary of Global Seed Vault
Changins, 14.03.2018 - Agroscope went to Svalbard, Norway, to celebrate the tenth anniversary of the Global Plant Seed Vault, where over a million seed varieties from all around the world are stored in duplicate.
Medicine/Pharmacology - Life Sciences
09.03.2018
Colorectal cancer: Screening should include environment, genetic factors
ANN ARBOR-When it comes to colorectal cancer, many people would benefit from individually tailored screening rather than standardized population guidelines. A new risk-prediction model, built by researchers at the University of Michigan and the Fred Hutchinson Cancer Research Center (Fred Hutch) in Seattle and colleagues, assesses the impact of environment and genetic factors on the development of colorectal cancer.
Medicine/Pharmacology - Life Sciences
08.03.2018
How cellular structure orchestrates immunologic memory
How cellular structure orchestrates immunologic memory
With every infection or vaccination, memory cells form that the body uses to remember the pathogen. This has been known for decades - but the structure of this cellular immunologic memory has previously proven impossible to pin down.
Life Sciences - Medicine/Pharmacology
08.03.2018
Neuro XXceptional: Celebrating exceptional women
Women scientists and clinicians are creators and changemakers, expanding the boundaries of human knowledge The Neuro has launched Neuro XXceptional - an exciting new year-long video series featuring
Medicine/Pharmacology - Life Sciences
06.03.2018
Novartis’ Xolair recommended in new global chronic urticaria guideline
Xolair (omalizumab), indicated as add-on therapy for the treatment of chronic spontaneous urticaria (CSU) , is the only therapy recommended by the guideline for patients unresponsive to antihistamine
Life Sciences - Mathematics
28.02.2018
Medicine/Pharmacology - Life Sciences
26.02.2018
The onset of Alzheimer’s disease: the importance of family history
You're about to turn 60, and you're fretting. Your mother has had Alzheimer's disease since the age of 65. At what age will the disease strike you? A Canadian study published in JAMA Neurology shows that the closer a person gets to the age at which their parent exhibited the first signs of Alzheimer's, the more likely they are to have amyloid plaques, the cause of the cognitive decline associated with the disease, in their brain.
Life Sciences - Medicine/Pharmacology
20.02.2018
Architecture of cellular control center mTORC2 elucidated
Architecture of cellular control center mTORC2 elucidated
The protein complex mTORC2 controls cellular lipid and carbohydrate metabolism. Researchers from the Biozentrum of the University of Basel and the ETH Zurich have now succeeded in deciphering the 3D structure of this important protein complex.
Life Sciences - Medicine/Pharmacology
20.02.2018
Products derived from plants offer potential as dual-targeting agents for experimental cerebral malaria
Malaria, a life-threatening disease usually caused when parasites from the Plasmodium family enter the bloodstream of a person bitten by a parasite-carrying mosquito, is a severe health threat globally, with 200 to 300 million cases annually and 445,000 deaths in 2016.
Life Sciences - Medicine/Pharmacology
19.02.2018
The Neuro joins neuroscience data sharing partnership
Canadian Open Neuroscience Platform will make disseminating and publishing data easier Modern neuroscience research can produce massive amounts of data, which researchers can use to find patterns rev
Life Sciences - Medicine/Pharmacology
15.02.2018
Najafabadi, Trenholm named Alfred P. Sloan Research Fellows
Hamed Najafabadi , an assistant professor in McGill's Department of Human Genetics, and Stuart Trenholm , assistant professor at the Montreal Neurological Institute, have been selected as 2018 Alfred
Medicine/Pharmacology - Life Sciences
15.02.2018
Not being aware of memory problems predicts onset of Alzheimer’s disease
Doctors who work with individuals at risk of developing dementia have long suspected that patients who do not realize they experience memory problems are at greater risk of seeing their condition wor
Life Sciences - Environment/Sustainable Development
01.02.2018
Norway rats trade different commodities
Norway rats trade different commodities
Researchers of the University of Bern have shown for the first time in an experiment that also non-human animals exchange different kind of favours. Humans commonly trade different commodities, which is considered a core competence of our species. However, this capacity is not exclusively human as Norway rats exchange different commodities, too.
Life Sciences - Medicine/Pharmacology
31.01.2018
Lab-on-a-chip for tracking single bacterial cells
Lab-on-a-chip for tracking single bacterial cells
Researchers at the Biozentrum of the University of Basel, together with researchers from the Max Planck Institute in Dresden, have set up a novel lab-on-a-chip with accompanying automatic analysis software.
Medicine/Pharmacology - Life Sciences
31.01.2018
Novartis announces NEJM publication of updated analysis from ELIANA trial showing longer-term durable remissions with Kymriah(TM) in children, young adults with r/r ALL
Novartis announces NEJM publication of updated analysis from ELIANA trial showing longer-term durable remissions with Kymriah(TM) in children, young adults with r/r ALL Analysis of 75 patients with m
Medicine/Pharmacology - Life Sciences
24.01.2018
Novartis exclusively licenses first ophthalmology gene therapy in all markets outside the US, a milestone for patients with rare inherited vision loss
Novartis exclusively licenses first ophthalmology gene therapy in all markets outside the US, a milestone for patients with rare inherited vision loss Novartis enters into a licensing and supply agre
Life Sciences - Medicine/Pharmacology
23.01.2018
A bacterial powder for quickly stabilizing soils
A bacterial powder for quickly stabilizing soils
EPFL's Laboratory of Soil Mechanics has developed an easily reproducible technique using bacteria and urea to reinforce sandy or gravelly terrain.
Life Sciences - Medicine/Pharmacology
23.01.2018
A bacterial powder for quickly stabilizing gravel surfaces
A bacterial powder for quickly stabilizing gravel surfaces
EPFL's Laboratory of Soil Mechanics has developed an easily reproducible technique using bacteria and urea to reinforce sandy or gravelly terrain.
Innovation/Technology - Life Sciences
18.01.2018
Medicine/Pharmacology - Life Sciences
17.01.2018
Novartis granted US FDA Priority Review for Kymriah(TM) (tisagenlecleucel), formerly CTL019, for adults with r/r DLBCL
Filing acceptance marks second Priority Review granted to Kymriah by the FDA for two distinct indications, underscoring the potential of first ever FDA-approved CAR-T therapy   EMA granted accelerate
Life Sciences - Computer Science/Telecom
11.01.2018
Blue Brain Nexus: an open-source tool for data-driven science
Knowledge sharing is an important driving force behind scientific progress. In an open-science approach, EPFL's Blue Brain Project has created and open sourced Blue Brain Nexus that allows the building of data integration platforms.
Medicine/Pharmacology - Life Sciences
09.01.2018
Novartis advances head-to-head superiority trials of Cosentyx versus Humira * and proposed biosimilar adalimumab**
SURPASS is the first head-to-head superiority trial versus proposed biosimilar adalimumab** in ankylosing spondylitis (AS) EXCEED is the first head-to-head superiority trial versus Humira * in psoria
Medicine/Pharmacology - Life Sciences
03.01.2018
Novartis Kisqali received FDA Breakthrough Therapy designation for initial endocrine-based treatment in premenopausal women with HR+/HER2- advanced breast cancer
Novartis Kisqali received FDA Breakthrough Therapy designation for initial endocrine-based treatment in premenopausal women with HR+/HER2- advanced breast cancer Designation based on Phase III MONALEESA-7 results demonstrating superior efficacy of Kisqali in combination with oral endocrine therapy compared to oral endocrine therapy in preor perimenopausal women who received no prior endocrine therapy for advanced disease Treatment benefit with K
Life Sciences - Medicine/Pharmacology
27.12.2017
Callous and Unemotional Traits Show in Brain Structure of Boys Only
Callous and Unemotional Traits Show in Brain Structure of Boys Only
Callous-unemotional traits are linked to differences in brain structure in boys, but not girls. This reports a European research team led by the University of Basel and University of Basel Psychiatric Hospital in a study on brain development in 189 adolescents.
Medicine/Pharmacology - Life Sciences
21.12.2017
European Commission approves Roche’s Alecensa (alectinib) as first-line treatment in ALK-positive lung cancer
European Commission approves Roche's Alecensa (alectinib) as first-line treatment in ALK-positive lung cancer Alecensa provides a new treatment option for people with newly diagnosed ALK-positive NSC
Medicine/Pharmacology - Life Sciences
12.12.2017
Roche announces phase III data showing Venclexta/Venclyxto plus MabThera/Rituxan reduced the risk of disease progression or death by 83% compared to a standard of care regimen in previously treated chronic lymphocytic leukaemia
Roche announces phase III data showing Venclexta/Venclyxto plus MabThera/Rituxan reduced the risk of disease progression or death by 83% compared to a standard of care regimen in previously treated c
Medicine/Pharmacology - Life Sciences
12.12.2017
Medicine/Pharmacology - Life Sciences
11.12.2017
Using 3D cell cultures to fight anti-cancer therapy resistance
Using 3D cell cultures to fight anti-cancer therapy resistance
An international research team headed by the University of Bern and the Netherlands Cancer Institute has developed 3D cell cultures in which genes can be specifically modified. They allow the study of genes that may cause therapy resistance in breast cancer. This knowledge may further improve the use of targeted anti-cancer drugs.
Life Sciences - Environment/Sustainable Development
11.12.2017
Medicine/Pharmacology - Life Sciences
10.12.2017
Primary analysis results from Novartis pivotal JULIET trial show Kymriah(TM) (tisagenlecleucel) sustained complete responses at six months in adults with r/r DLBCL, a difficult-to-treat cancer
Primary analysis results from Novartis pivotal JULIET trial show Kymriah(TM) (tisagenlecleucel) sustained complete responses at six months in adults with r/r DLBCL, a difficult-to-treat cancer At six
Life Sciences - Medicine/Pharmacology
08.12.2017
Acrobatic Duo in the Cells
Acrobatic Duo in the Cells
Just like an acrobatic duo, some proteins lend each other stability. Researchers at the Biozentrum of the University of Basel have discovered that the protein ‘Trigger factor' recognizes a partner by instable, flexible domains, to then together form a stable protein duo. The study has been published in the current issue of ‘Nature Communications'.
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