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Life Sciences - Environment - 12.11.2020
Two lakes, seven whitefish species
Two lakes, seven whitefish species
In the journal ZooKeys, a group of scientists from Eawag and Bern University have described seven whitefish species endemic to the Bernese Oberland lakes - including four not previously described scientifically, two of which have only been identified as distinct species in the last few years.

Materials Science - Life Sciences - 06.11.2020
New light on cellular hydration
New light on cellular hydration
Researchers from EPFL's Institute of Bioengineering and the University of Geneva have teamed up to develop new tools for studying water flow across cell membranes.

Health - Life Sciences - 05.11.2020

Life Sciences - Health - 05.11.2020
A new generation of optogenetic tools for research and medicine
A new generation of optogenetic tools for research and medicine
The European Research Council (ERC) is providing 10 million euros in funding for an interdisciplinary, collaborative project in the structural and biophysical analysis of selected photoreceptors and t

Health - Life Sciences - 04.11.2020

Health - Life Sciences - 03.11.2020
Significant vulnerability in prostate cancer detected
Significant vulnerability in prostate cancer detected
Researchers at the University of Bern led an international team that has identified a novel vulnerability in advanced prostate cancer that is no longer responding to hormonal therapy. These findings could lead to the development of new treatment approaches for men suffering from the most aggressive form of prostate cancer.

Life Sciences - Computer Science - 02.11.2020
Building artificial neural networks inspired by the brain
Building artificial neural networks inspired by the brain
The requirements of real biological neural networks are modest compared to the complex deep neural networks used in machine learning, which come with substantial memory and energy demands. The Zenke group have developed a new method in machine learning called Neural Tangent Transfer to make a sparse neural network which performs almost as well as densely connected deep neural network on various learning tasks, but at a heavily reduced computing cost.

Life Sciences - 21.10.2020
How the visual cortex combines movement and vision
How the visual cortex combines movement and vision
The Keller group had previously shown that the coupling of sensory and motor experience was critical for normal sensorimotor processing. The researchers have now identified the particular subset of cortical neurons responsible for computing mismatches between what we expect to see based on movement and what we actually see, and are likely essential for helping us distinguish between self-generated and externally generated sensations.

Life Sciences - 15.10.2020

Health - Life Sciences - 29.09.2020
MarrowQuant: a new digital-pathology tool
MarrowQuant: a new digital-pathology tool
Scientists have developed a digital pathology tool for quantifying bone marrow compartments in standard histological sections. Named "MarrowQuant", the software makes it possible to examine bone marrow biopsies as well as to re-examine historical collections of bone-marrow samples and even old clinical trials.

Life Sciences - Environment - 29.09.2020
Wildcats threatened by their domestic cousins
Wildcats threatened by their domestic cousins
Wildcats in the Swiss Jura will undergo an irreversible genetic replacement by domestic cats if no preventive measures are taken. European wildcats, thought to be extinct 50 or so years ago in the Jura mountains, have since recolonised part of their former territory. This resurgence in an area occupied by domestic cats has gone hand-in-hand with genetic crosses between the two species.

Health - Life Sciences - 29.09.2020
MarrowQuant: a digital-pathology tool
MarrowQuant: a digital-pathology tool
Scientists have developed a digital pathology workflow for quantifying bone marrow compartments in standard histological sections. Named "MarrowQuant", this workflow based on the open source software QuPath makes it possible to examine bone marrow biopsies as well as to re-examine historical collections of bone-marrow samples and even old clinical trials.

Physics - Life Sciences - 25.09.2020

Life Sciences - Chemistry - 21.09.2020

Life Sciences - Chemistry - 21.09.2020
How to make a replication origin in multicellular eukaryotes
How to make a replication origin in multicellular eukaryotes
Loading of replicative helicases onto DNA is a key event during the initiation of chromosomal DNA replication.

Life Sciences - Health - 15.09.2020
Catalyst Fund selects six projects in its 2020 funding round
The Catalyst Fund - supported by the Bertarelli Foundation - has selected six research projects to fund this year. Led by professors from EPFL and other Swiss Universities, these projects all aim to develop new treatment options for neurological disorders. Created by the Bertarelli Foundation in 2017, the Catalyst Fund aims to invest in translational projects targeting innovative approaches for diseases affecting the brain, spinal cord, peripheral nervous system and sensory organs.

Environment - Life Sciences - 11.09.2020
The cold memory of the earth
The cold memory of the earth
On September 14, an expedition within the framework of the international project Ice Memory is setting out to carry out ice core drilling on the glacier of the mountain massif Grand Combin in the Swiss canton of Valais.

Health - Life Sciences - 08.09.2020
LifeTime - Researchers partner to improve European healthcare
LifeTime - Researchers partner to improve European healthcare
The FMI is a partner of the pan-European LifeTime initiative. In two publications, researchers involved with the initiative - including FMI group leader Susan Gasser - present a detailed roadmap of how to leverage the latest scientific breakthroughs and technologies over the next decade, to track, understand and treat human cells throughout an individual's lifetime.

Life Sciences - Health - 07.09.2020
How to identify new molecular glue degraders
How to identify new molecular glue degraders
Molecular glue degraders are a new class of drugs that work by facilitating an interaction between a disease-causing target protein and a ubiquitin ligase complex, tagging the target protein for degradation.

Life Sciences - Research Management - 03.09.2020

Life Sciences - Chemistry - 31.08.2020
FMI is a partner in the new EU “HCA|Organoid? project
FMI is a partner in the new EU “HCA|Organoid” project
Organoid? was launched today. It aims at validating organoids as faithful models of human biology, combining single-cell profiling and organoid technology.

Life Sciences - 25.08.2020

Health - Life Sciences - 24.08.2020
Breast cancer: New way for tumor cells to escape self-destruction
Breast cancer: New way for tumor cells to escape self-destruction
In the body, so-called programmed cell death prevents cells with irreparable damage from surviving and turning into cancer cells. In the "EMBO Journal", researchers at the University of Basel's Biozentrum, report how a certain protein variant thwarts the self-destruction and thus promotes the growth of breast cancer cells.

Life Sciences - 21.08.2020
The trick of proteins that
The trick of proteins that "slice" the DNA to recombine it
When our DNA breaks, cells use the so-called homologous recombination pathway to accurately repair the break, so that DNA is fixed and no mutations are introduced during the repair process. When multiple DNA molecules are broken, the recombination factors use a smart strategy to join only the DNA pieces originating from the same DNA molecules.

Health - Life Sciences - 18.08.2020
UZH Introduces Five New University Research Priority Programs
The University of Zurich is introducing five new University Research Priority Programs focusing on equal opportunities, human reproduction, rare diseases, digital religions and basic principles of learning.

Physics - Life Sciences - 14.08.2020

Health - Life Sciences - 13.08.2020
IOR takes part in innovative project for real-time Covid-19 testing device
SARS-CoV-2 virus analysis involves complex procedures and requires long waiting times.

Computer Science - Life Sciences - 11.08.2020
Blackrock Microsystems Licenses Wyss Center's Real-time Neural Signal Processing Platform
Blackrock Microsystems Licenses Wyss Center’s Real-time Neural Signal Processing Platform
The software platform, NeuroKey, interfaces with multiple brain signal acquisition sources and devices, extending the reach of brain-computer interface applications GENEVA, SWITZERLAND & SALT LAKE CITY, UTAH, USA - The Wyss Center for Bio and Neuroengineering has granted a worldwide license to Blackrock Microsystems to commercialize its neural signal processing and decoding software platform for research and clinical applications.

Life Sciences - Health - 11.08.2020
Wyss Center and Osypka announce collaboration
Wyss Center and Osypka announce collaboration
Pushing the boundaries of implantable neuro-device development Today the Wyss Center for Bio and Neuroengineering, Geneva, Switzerland and OSYPKA AG/OSYPKA Medtec, Rheinfelden, Germany and Longmont,

Health - Life Sciences - 28.07.2020
Immunoprotein impairs Sars-Cov-2
An international team with researchers of the Institute of Virology and Immunology (IVI) of the University of Bern and the Swiss Federal Food Safety and Veterinary Office (FSVO) showed that an endogenous protein prevents the virus from fusing with host cells.

Health - Life Sciences - 22.07.2020

Life Sciences - Computer Science - 09.07.2020
Restoring Vision Through Electrical Stimulation
Restoring Vision Through Electrical Stimulation
In a project under Horizon 2020, researchers from seven European organizations will examine how the vision of visually impaired people can be restored using electrical stimulation of the brain.

Life Sciences - Health - 30.06.2020
Next-Generation Sequencing to provide Precision medicine for Rare Metabolic Disorders
Next-Generation Sequencing to provide Precision medicine for Rare Metabolic Disorders
Advances in next-generation-sequencing technology that allow researchers to look at billions of pieces of genetic information are changing the way a disease is diagnosed. Correct identification of changes in the human genetic code responsible for rare metabolic disorders provides scientists and physicians with fact-based guidelines for the treatment.

Life Sciences - Health - 25.06.2020
Handing over the keys at Früebüel
Handing over the keys at Früebüel
Despite the coronavirus lockdown, the renovation and extension of Früebüel research station in Walchwil (Canton of Zug) was completed nearly on schedule.

Pharmacology - Life Sciences - 19.06.2020

Life Sciences - 11.06.2020
How transcription factors recognize binding motifs on chromatin
How transcription factors recognize binding motifs on chromatin
In a video (5'35'') combining interviews and figures, the team behind the latest collaboration from the Thomä and Schübeler labs - Alicia Michael, Ralph Grand and Luke Isbel - explain how they developed an assay identifying where the preferable sites for the transcription factor-DNA binding motif on the nucleosome were, so that they could build transcription factor-nucleosome complexes.

Health - Life Sciences - 05.06.2020
Microbiology offers relief for
Microbiology offers relief for "colicky" babies
Vanesa Rocha Martin is studying how bacteria can be used to treat infant colic. As part of her Pioneer Fellowship, she is now turning her findings into a first-line therapy with a proven effect.

Life Sciences - Health - 04.06.2020
Heralding a new era in protein analytics
Heralding a new era in protein analytics
Systems biologist Paola Picotti receives this year's Rössler Prize for her groundbreaking work in the field of proteomics.

Life Sciences - Environment - 03.06.2020
On the trail of symbiont diversity
On the trail of symbiont diversity
Parasitic wasps act as biological weapons against aphids in pest control. With the help of symbionts, however, some aphids try to defend themselves against the attacks. The struggle between these insects is one of the specialities of Christoph Vorburger, head of the "Aquatic Ecology" department and evolutionary ecologist Nina Hafer-Hahmann, postdoc in the same department.

Life Sciences - Veterinary - 02.06.2020
Designing animal studies to improve research reproducibility and reduce animal use
At the invitation of the University of Bern, international experts worked out new recommendations for the design of animal studies. They encourage a paradigm shift to improve the reproducibility of scientific results and reduce animal numbers. Animal experiments are typically conducted under highly standardized laboratory conditions.

Life Sciences - 28.05.2020
Genetics of nuptial coloration facilitates the persistence of co-occurring species
Genetics of nuptial coloration facilitates the persistence of co-occurring species
Around 500 different cichlid species are found in Lake Victoria. According to a study by scientists at Eawag and Bern University, whether closely related species can persist within the same area depends on the effect sizes of individual genes underlying key mate-choice traits. In several eastern African lakes, an immense variety of cichlid species evolved within just a few thousand years.

Health - Life Sciences - 08.05.2020
More Selective Elimination of Leukemia Stem Cells and Blood Stem Cells
More Selective Elimination of Leukemia Stem Cells and Blood Stem Cells
Hematopoietic stem cells from a healthy donor can help patients suffering from acute leukemia. However, the side effects of therapies are often severe. A group of researchers led by the University of Zurich have now shown how human healthy and cancerous hematopoietic stem cells can be more selectively eliminated using immunotherapy instead of chemotherapy in mice.
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