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Medicine / Pharmacology - Life Sciences - 12:30
University of Basel and ETH Zurich combine cutting-edge research for children and adolescents worldwide
University of Basel and ETH Zurich combine cutting-edge research for children and adolescents worldwide
Today, the University of Basel and ETH Zurich co-founded the Botnar Research Centre for Child Health (BRCCH) in Basel.

Life Sciences - 18.09.2018

Careers / Employment - Life Sciences - 18.09.2018
Marie Heim-Vögtlin Prize 2018: Sara Montagner discovers the epigenetic secrets of mast cells
Epigenetic modifications of our DNA are a key aspect of the normal functioning of mast cells, which play an important role in immune reactions. Biologist Sara Montagner was able to demonstrate this in her work. She will receive this year's Marie Heim-Vögtlin Prize from the SNSF at the award ceremony in Bellinzona on 29 November 2018.

Medicine / Pharmacology - Life Sciences - 18.09.2018
University of Basel and ETH Zurich Combine Cutting-Edge Research for Children and Adolescents Worldwide
Today, the University of Basel and ETH Zurich co-founded the Botnar Research Centre for Child Health (BRCCH) in Basel.

Medicine / Pharmacology - Life Sciences - 13.09.2018
Novartis announces NEJM publication of landmark PARADIGMS study demonstrating significant benefit of Gilenya in children and adolescents with MS
Treatment with Gilenya (fingolimod) substantially reduced the debilitating impact of MS, with significant decreases in key measures of disease activity vs.

Medicine / Pharmacology - Life Sciences - 13.09.2018
Novartis real-world evidence confirms efficacy and safety benefits of Cosentyx in daily life for psoriasis patients
Real-world evidence confirms Cosentyx efficacy and safety consistent with previously reported clinical studies - Novartis presents a large program of real-world evidence at the 27 th European Academy of Dermatology and Venereology (EADV) Congress, adding to the robust body of clinical data supporting the use of Cosentyx in moderate-to-severe psoriasis - Cosentyx 5-year data in psoriasis from a Phase III study were presented in 2017 , proving lon

Medicine / Pharmacology - Life Sciences - 12.09.2018
Novartis survey shows psoriasis patients want treatment effect beyond clear skin
New patient preference survey confirms that patients value clear skin the most, but expect additional benefits from their treatment, such as proven long-term efficacy and safety data and no injection site reactions A separate ranking incorporating additional characteristics showed that effectiveness in treating multiple manifestations of psoriatic disease was also important The number of injections per dose and injection frequency were least imp

Life Sciences - Medicine / Pharmacology - 07.09.2018
Using biosensors to deliver personalized doses of antibiotics
A team of eight EPFL students won the technical prize in the SensUs international competition, designing a portable biosensor that can measure the amount of vancomycin in a patient's blood stream, enabling doctors to better control the dosage and reduce harmful side effects.

Medicine / Pharmacology - Life Sciences - 06.09.2018
A new home for ETH's Department in Basel
A new home for ETH’s Department in Basel
Today ETH Zurich celebrated the laying of the foundation stone for its new building on the Schällemätteli campus in Basel.

Life Sciences - 06.09.2018
ETH professor not guilty of manipulation
An independent commission of inquiry led by the French National Center for Scientific Research (CNRS) with the participation of ETH Zurich has investigated the publications of ETH Professor Olivier Voinnet's former research group at the CNRS. The inquiry uncovered manipulation of certain figures. However, the commission's report confirms that Voinnet did not personally initiate this manipulation.

Environment - Life Sciences - 03.09.2018
Art inspired by research - new AiL videos
Art inspired by research - new AiL videos
In 2017, two artists from Saudi Arabia spent some time at Eawag as part of the Artists in Labs (ail) project and were inspired by research into artistic interpretations, Zahrah Alghamdi and Muhannad Shono.

Medicine / Pharmacology - Life Sciences - 29.08.2018
European Commission approves Novartis combination therapy Tafinlar + Mekinist for adjuvant treatment of BRAF V600 mutation-positive melanoma
Approval based on COMBI-AD study demonstrating greater than 50% reduction in risk of disease recurrence or death in stage III melanoma patients    More than 50% of stage III melanoma patients are lik

Medicine / Pharmacology - Life Sciences - 27.08.2018
Novartis receives European Commission approval of its CAR-T cell therapy, Kymriah (tisagenlecleucel)
The EC approval is based on the first global CAR-T registration trials, which included patients from eight European countries and demonstrated durable responses and a consistent safety profile in r/r

Life Sciences - 23.08.2018
Movement control: how our brain responds to unexpected situations
Movement control: how our brain responds to unexpected situations
Scientists have demonstrated that the motor cortex is necessary for the execution of corrective movements in response to unexpected changes of sensory input but not when the same movements are executed spontaneously.

Medicine / Pharmacology - Life Sciences - 20.08.2018
China National Drug Administration grants rapid approval of Roche’s Alecensa (alectinib) as a treatment for ALK-positive lung cancer
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Medicine / Pharmacology - Life Sciences - 03.08.2018
PRIME designation granted by European Medicines Agency for RG6042 for treatment of Huntington’s disease
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Life Sciences - Environment - 25.07.2018
Scientists set out to explore microbial life in glacier streams
EPFL scientists will spend at least the next four years studying some of the world's biggest glacier-fed streams.

Medicine / Pharmacology - Life Sciences - 23.07.2018
Novartis renews drug donation of Egaten (triclabendazole) until 2022, reaffirming its commitment to the fight against liver fluke
Novartis extends agreement with the WHO for the donation of Egaten for the treatment of liver fluke, a neglected tropical disease, also known as fascioliasis, that infects more than 2.4 millio

Medicine / Pharmacology - Life Sciences - 20.07.2018
Roche to present new data demonstrating the breadth and depth of its Alzheimer’s programme at the upcoming Alzheimer’s Association International Conference
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Medicine / Pharmacology - Life Sciences - 19.07.2018
Roche’s Tecentriq in combination with pemetrexed and platinum-based chemotherapy reduced the risk of disease worsening or death in the initial treatment of people with advanced lung cancer
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Medicine / Pharmacology - Life Sciences - 18.07.2018
Novartis Kisqali now first and only CDK4/6 inhibitor indicated in US as first-line therapy specifically for premenopausal women; and as initial therapy with fulvestrant in postmenopausal women
Novartis Kisqali now first and only CDK4/6 inhibitor indicated in US as first-line therapy specifically for premenopausal women; and as initial therapy with fulvestrant in postmenopausal women Kisqal

Life Sciences - 10.07.2018
Wyss Center showcases research at La Nuit de la Science
Wyss Center showcases research at La Nuit de la Science
Campus Biotech joined forces with La Nuit de la Science for the first time and welcomed visitors onto campus for the duration of the two-day event The Wyss Center team showcased a new virtual reality

Environment - Life Sciences - 05.07.2018
Improving small hydropower planning
Improving small hydropower planning
Small hydropower plants are often constructed on alpine streams, where they may have adverse impacts on sensitive ecosystems. Little is known, however, about the particular effects of individual plants, or the cumulative effects of multiple plants within the same river system. The current state of knowledge has now been reviewed in a study by Eawag researchers.

Medicine / Pharmacology - Life Sciences - 29.06.2018
Novartis receives positive CHMP opinion for Kymriah for treating two aggressive blood cancers, marking important medical advance for patients in Europe
Novartis receives positive CHMP opinion for Kymriah for treating two aggressive blood cancers, marking important medical advance for patients in Europe First CHMP opinion for a CAR-T cell therapy in

Medicine / Pharmacology - Life Sciences - 21.06.2018
Claudia Daubenberger Appointed Professor at the University of Basel
Claudia Daubenberger Appointed Professor at the University of Basel
The University of Basel appointed Claudia Daubenberger, Head of Clinical Immunology at Swiss TPH, as professor of Infection Biology and Immunology within the Faculty of Science.

Medicine / Pharmacology - Life Sciences - 21.06.2018

Medicine / Pharmacology - Life Sciences - 16.06.2018
Novartis JULIET trial of Kymriah demonstrates more than one-year durability of responses in adults with relapsed or refractory DLBCL
Overall response rate was 52% and median duration of response was not reached at a median follow-up of 14 months, signifying responses were durable   Patients had a 65% chance of being relapse-free o

Medicine / Pharmacology - Life Sciences - 15.06.2018
Study of real-world data concludes Jakavi is associated with a reduction in risk of death and dangerous blood clots for patients with rare blood cancer
Novartis study of real-world data concludes Jakavi is associated with a reduction in risk of death and dangerous blood clots for patients with rare blood cancer Comparison of Jakavi (ruxolitinib) vs.

Medicine / Pharmacology - Life Sciences - 14.06.2018
Enigma of fatty acid metabolism solved: Enzyme shape controls its activity
Enigma of fatty acid metabolism solved: Enzyme shape controls its activity
Fats are essential for our body. The core components of all fats are fatty acids. Their production is initiated by the enzyme ACC.

Medicine / Pharmacology - Life Sciences - 02.06.2018
Phase III IMpower131 study showed Tecentriq(atezolizumab) plus chemotherapy (carboplatin and Abraxane) reduced the risk of disease worsening or death for people with advanced squamous non-small cell lung cancer
Phase III IMpower131 study showed Tecentriq(atezolizumab) plus chemotherapy (carboplatin and Abraxane) reduced the risk of disease worsening or death for people with advanced squamous non-small cell

Life Sciences - Computer Science / Telecom - 29.05.2018

Medicine / Pharmacology - Life Sciences - 29.05.2018
Phase III IMpower130 study showed Roche’s Tecentriq (atezolizumab) plus chemotherapy (carboplatin and Abraxane) helped people with metastatic non-squamous NSCLC live significantly longer compared to chemotherapy alone
Phase III IMpower130 study showed Roche's Tecentriq (atezolizumab) plus chemotherapy (carboplatin and Abraxane) helped people with metastatic non-squamous NSCLC live significantly longer compared to

Life Sciences - Chemistry - 22.05.2018
Designer cells: artificial enzyme can activate a gene switch
Designer cells: artificial enzyme can activate a gene switch
Complex reaction cascades can be triggered in artificial molecular systems: Swiss scientists have constructed an enzyme than can penetrate a mammalian cell and accelerate the release of a hormone.

Medicine / Pharmacology - Life Sciences - 17.05.2018
Novartis data at ASCO and EHA reinforce company’s commitment to reimagining cancer
Results from the Kisqali MONALEESA clinical trial program, the largest industrysponsored Phase III registration program researching a CDK4/6 inhibitor in HR+/HER2- advanced breast cancer, will be pre

Life Sciences - Medicine / Pharmacology - 17.05.2018
Blocking two enzymes could make cancer cells mortal
EPFL scientists have identified two enzymes that protect chromosomes from oxidative damage and shortening.

Medicine / Pharmacology - Life Sciences - 17.05.2018
Follow-up phase III data showed Roche’s Alecensa helped people with ALK-positive metastatic non-small cell lung cancer live a median of almost three years without their disease worsening or death
Follow-up phase III data showed Roche's Alecensa helped people with ALK-positive metastatic non-small cell lung cancer live a median of almost three years without their disease worsening or death Inv

Medicine / Pharmacology - Life Sciences - 17.05.2018
Phase III IMpower150 study showed Roche’s Tecentriq and Avastin plus carboplatin and paclitaxel helped people with a specific type of metastatic lung cancer live significantly longer compared to Avastin plus carboplatin and paclitaxel
Phase III IMpower150 study showed Roche's Tecentriq and Avastin plus carboplatin and paclitaxel helped people with a specific type of metastatic lung cancer live significantly longer compared to Avas

Life Sciences - Medicine / Pharmacology - 16.05.2018
Cellular Valve Structure Opens Up Potential Novel Therapies
Cellular Valve Structure Opens Up Potential Novel Therapies
Human cells are enclosed by membranes and are in osmotic equilibrium with their environment. If the concentration of solute molecules (osmolarity) in the fluid surrounding the cells decreases, cells start to swell; in extreme cases, this can result in the cells bursting.

Medicine / Pharmacology - Life Sciences - 12.05.2018
Novartis announces FDA approval of Gilenya as the first disease-modifying therapy for pediatric relapsing multiple sclerosis
New approval for Gilenya (fingolimod) addresses strong unmet need for younger patients, who often experience more frequent relapses than adults with multiple sclerosis (MS)   In a landmark controlled

Life Sciences - Medicine / Pharmacology - 09.05.2018
Human MAIT cells sense the metabolic state of enteric bacteria
Human MAIT cells sense the metabolic state of enteric bacteria
A little-explored group of immune cells plays an important role in the regulation of intestinal bacteria. Changing metabolic states of the microbes have an effect on defense cells at different stages of alert or rest, as researchers from the Department of Biomedicine at the University and University Hospital of Basel report in the journal "Mucosal Immunology." It is known that the metabolites of bacteria influence the composition and function of immune cells resident within the gut.

Innovation / Technology - Life Sciences - 02.05.2018

Life Sciences - Medicine / Pharmacology - 25.04.2018
How to profit from biowaste
How to profit from biowaste
April 25, 2018, Organisation & Staff Water & Development Researchers of the Eawag department Sanitation, Water and Solid Waste for Development (Sandec) and ETH Zurich are developing a method to produce animal feed from biowaste products.
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