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Health - Pharmacology - 28.01.2020
The universities of Bern and Zurich offer continuing education in gender-specific medicine
The universities of Bern and Zurich offer continuing education in gender-specific medicine
There is increasing evidence that health behavior and disease manifestation differ substantially between women and men.

Pharmacology - Health - 27.01.2020
Roche submits supplemental Biologics License Application to the FDA for Tecentriq in combination with Avastin for the most common form of liver cancer
Application is being reviewed under FDA's Real-Time Oncology Review pilot programme Roche today announced the completion of a supplemental Biologics License Application (sBLA) submission to the US Fo

Pharmacology - 22.01.2020

Pharmacology - Health - 21.01.2020
European Commission approves Roche’s Polivy for people with previously treated aggressive lymphoma
Novel combination regimen includes first-in-class antibody-drug conjugate that specifically targets CD79b Targeted off-the-shelf treatment provides much-needed new option for people with relapsed or

Pharmacology - Health - 20.01.2020
Novartis announces EU approval of Mayzent (siponimod) for adult patients with secondary progressive multiple sclerosis (SPMS) with active disease
Patients & Caregivers Healthcare Professionals Society & ESG Mayzent (siponimod) is the first and only oral treatment specifically indicated for patients with secondary progressive multiple s

Health - Pharmacology - 15.01.2020
Genome editing at the crossroads of scandal and cure
Genetic modification of babies in China one year ago was universally condemned. At the same time, CRISPR treatments are on their way into our clinics.

Health - Pharmacology - 09.01.2020
One out of every two transplant recipients at risk of infection
One out of every two transplant recipients at risk of infection
Swiss researchers, including UNIGE, show that 50% of transplant recipients develop severe infections within a year of the operation, which can lead to death.

Pharmacology - Health - 09.01.2020
Novartis ligelizumab (QGE031) more effective than Xolair at inhibiting immunoglobulin E pathway responsible for chronic spontaneous urticaria
Patients & Caregivers Healthcare Professionals Society & ESG Data show ligelizumab binds to immunoglobulin E (IgE), a key driver of chronic spontaneous urticaria (CSU), with significantly hig

Pharmacology - Health - 16.12.2019
Novartis provides update on LUSTER Phase III studies in patients with uncontrolled GINA 4/5 asthma
Patients & Caregivers Healthcare Professionals Society & ESG Pooled analyses of LUSTER 1 and 2 did not support further development of Fevipiprant in asthma as a primary indication   Fevipipra

Pharmacology - Health - 16.12.2019

Pharmacology - Health - 13.12.2019
Novartis receives positive CHMP opinion for Beovu (brolucizumab) for the treatment of wet AMD
Patients & Caregivers Healthcare Professionals Society & ESG In two head-to-head clinical trials, patients on Beovu achieved vision gains that were non-inferior to aflibercept at year one 1  

Pharmacology - Health - 13.12.2019
Roche announces positive Phase III study results for Tecentriq plus Cotellic and Zelboraf in people with previously untreated BRAF V600 mutation-positive advanced melanoma
Roche today announced the Phase III IMspire150 study, in people with previously untreated BRAF V600 mutation-positive advanced melanoma, met its primary endpoint of progression-free survival (PFS).

Pharmacology - Health - 12.12.2019
Roche’s fixed-dose subcutaneous combination of Perjeta and Herceptin comparable to intravenous formulations in people with HER2-positive breast cancer
Fixed-dose combination administered under the skin in just minutes, compared to hours with intravenous administration, significantly reducing time spent receiving treatment Phase III FeDeriCa study s

Pharmacology - Health - 11.12.2019
APHINITY six-year results strengthen evidence of clinical benefit with Roche’s Perjeta-based regimen
Greatest improvement in invasive disease-free survival (iDFS) remains in patients at high risk of recurrence, such as those with lymph node-positive disease with a 28% reduction in the risk of recurr

Health - Pharmacology - 11.12.2019
Novartis Kisqali data show superior overall survival compared to fulvestrant and consistent efficacy across advanced breast cancer patient subgroups in MONALEESA-3
Patients & Caregivers Healthcare Professionals Society & ESG MONALEESA-3 paper published today in The New England Journal of Medicine shows statistically significant overall survival results

Health - Pharmacology - 10.12.2019
Roche receives CE Mark for its Accu-Chek SugarView app
Accu-Chek SugarView is the first app that determines blood glucose ranges by taking photos with the smartphone camera without the need of a blood glucose meter.

Pharmacology - Health - 09.12.2019
Novartis Kymriah demonstrates consistent efficacy and safety outcomes in US patients when used in real-world setting
Patients & Caregivers Healthcare Professionals Society & ESG Efficacy in DLBCL confirmed results seen in the pivotal trial despite treatment of a broader population, including older and more

Health - Pharmacology - 09.12.2019
Novartis global survey uncovers profound and often under-reported effects on sickle cell disease patients
Patients & Caregivers Healthcare Professionals Society & ESG Findings from more than 2,000 respondents in 16 countries underscore the debilitating and under-reported effects of sickle cell di

Pharmacology - Health - 08.12.2019
New data demonstrate the continued clinical benefit of fixed-duration, chemotherapy-free Venclexta/Venclyxto-based treatments in chronic lymphocytic leukaemia
In an updated analysis of the CLL14 study, Venclexta/Venclyxto plus Gazyva/Gazyvaro achieved remissions that were sustained over time in people with previously untreated chronic lymphocytic leukaemia

Pharmacology - Health - 06.12.2019
Novartis Phase III data on new inhaled dual combination QMF149 show significant improvement across key asthma outcomes versus monotherapy
Patients & Caregivers Healthcare Professionals Society & ESG Once-daily QMF149 met primary endpoint of lung function improvement and key secondary endpoint of asthma control improvement versu

Pharmacology - Health - 04.12.2019
FDA approves Roche’s Tecentriq plus chemotherapy (Abraxane and carboplatin) for the initial treatment of metastatic non-squamous non-small cell lung cancer
Approval based on the Phase III IMpower130 study showing the Tecentriq plus chemotherapy combination demonstrated a significant overall survival and progression-free survival benefit Roche today anno

Pharmacology - Health - 02.12.2019
Novartis breadth of data at 2019 ASH demonstrates commitment to reimagining medicine in hematology through innovative therapeutic platforms
Patients & Caregivers Healthcare Professionals Society & ESG With more than 140 abstracts, Novartis continues its leadership in hematology innovation   Data for MBG453, an innovative anti-TIM

Health - Pharmacology - 02.12.2019

Health - Pharmacology - 02.12.2019
Improving Tuberculosis Screening in Remote Areas
Improving Tuberculosis Screening in Remote Areas
Every year, 1.5 million people die from tuberculosis (TB) worldwide. Diagnosis and treatment is particularly difficult in remote rural areas.

Pharmacology - Health - 02.12.2019
Positive phase III results for Roche’s satralizumab in neuromyelitis optica spectrum disorder published in the New England Journal of Medicine
Satralizumab demonstrated robust efficacy, sustained for 144 weeks, in significantly reducing the risk of relapse in combination with baseline immunosuppressant therapy Satralizumab targets the interleukin-6 (IL-6) receptor, a potential key driver of neuromyelitis optica spectrum disorder (NMOSD) NMOSD is a rare, debilitating autoimmune disease of the central nervous system that can cause visual impairment, motor disability and even death Roche

Pharmacology - Health - 25.11.2019
FDA grants priority review to Roche’s risdiplam for spinal muscular atrophy
Filing submission includes 12-month data from pivotal FIREFISH and SUNFISH trials in a broad population of people living with Types 1, 2 or 3 SMA Roche today announced that the U.S. Foo

Health - Pharmacology - 22.11.2019
Roche presents pivotal data demonstrating Tecentriq in combination with Avastin improves overall survival in people with the most common form of liver cancer
First Phase III cancer immunotherapy study to show an improvement in overall survival and progression-free survival in people with unresectable hepatocellular carcinoma compared with sorafenib Result

Pharmacology - Health - 18.11.2019
Roche to present new and updated data for seven approved and investigational medicines across multiple types of breast cancer at the 2019 San Antonio Breast Cancer Symposium
Study results reflect advancements in HER2-positive, triple-negative, and hormone receptor-positive breast cancer Follow-up data from pivotal phase III APHINITY study evaluating Perjeta plus Hercepti

Pharmacology - Health - 17.11.2019
Novartis PARAGON-HF analyses suggest Entresto benefit beyond HFrEF
Patients & Caregivers Healthcare Professionals Society & ESG Entresto (sacubitril/valsartan) demonstrated greatest benefit in HFpEF patients with ejection fractions adjacent to HFrEF, compare

Pharmacology - Health - 15.11.2019
New Novartis medicine Adakveo (crizanlizumab) approved by FDA to reduce frequency of pain crises in individuals living with sickle cell disease
Patients & Caregivers Healthcare Professionals Society & ESG Sickle cell pain crises are unpredictable, severe events associated with life-threatening complications 1   Adakveo reduced the an

Pharmacology - Health - 15.11.2019
Novartis receives positive CHMP opinion for Mayzent (siponimod) for the treatment of adult patients with active secondary progressive multiple sclerosis (SPMS)
Patients & Caregivers Healthcare Professionals Society & ESG If approved, Mayzent (siponimod) will be the first and only oral treatment specifically indicated for patients with active seconda

Pharmacology - Health - 15.11.2019
CHMP recommends conditional EU approval of Roche’s Polivy for people with previously treated aggressive lymphoma
First-in-class antibody-drug conjugate that specifically targets CD79b, a protein expressed in the majority of B-cells Targeted off-the-shelf treatment represents potential new option for people with

Pharmacology - Health - 15.11.2019
CHMP recommends EU approval of Roche’s Kadcyla for the adjuvant treatment of people with HER2-positive early breast cancer with residual invasive disease after neoadjuvant treatment
Kadcyla cut the risk of disease recurrence or death by half compared to Herceptin in the adjuvant setting for specific patients with HER2-positive early breast cancer At three years, 88.3% of

Pharmacology - Health - 12.11.2019
New Novartis PREVENT data show Cosentyx delivers early relief in axial spondyloarthritis
Patients & Caregivers Healthcare Professionals Society & ESG 42.2% of patients with non-radiographic axial spondyloarthritis (nr-axSpA) treated with Cosentyx had improved ASAS40 scores

Health - Pharmacology - 12.11.2019
Sandoz presents real-world data showing effectiveness of Erelzi (etanercept-szzs) in rheumatic disease treatment
Patients & Caregivers Healthcare Professionals Society & ESG Interim results from COMPACT, a multi-country, real-world study of Erelzi for approved rheumatic diseases presented at 2019 ACR/AR

Pharmacology - Health - 11.11.2019
Roche’s Gazyva (obinutuzumab), in combination with standard of care, more than doubles the percentage of lupus nephritis patients achieving complete renal response, compared to standard of care alone
NOBILITY phase II study showed 40% of patients treated with Gazyva plus standard of care achieved complete renal response at Week 76, compared to 18% of patients treated with placebo plus standard of

Pharmacology - Life Sciences - 11.11.2019
Roche’s risdiplam meets primary endpoint in pivotal SUNFISH trial in people with type 2 or 3 spinal muscular atrophy
Study demonstrated statistically significant improvements in the overall study population with Type 2 or 3 SMA No treatment related safety findings leading to withdrawal seen in any risdiplam trial t

Pharmacology - Health - 01.11.2019
Novartis Cosentyx shows encouraging results versus Humira * from first-of-its-kind head-to-head trial in psoriatic arthritis
Cosentyx narrowly missed statistical significance for superiority in ACR 20, the primary endpoint of the EXCEED trial, while showing numerically higher results versus Humira *   Statistically signifi

Pharmacology - Life Sciences - 30.10.2019
Novartis announces AVXS-101 intrathecal study update
FDA placed a partial hold on AVXS-101 intrathecal clinical trials for SMA patients based on findings in a small pre-clinical animal study Adverse events that might be expected from the pre-clinical f
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