Fructose metabolism and noncommunicable diseases: recent findings and new research perspectives

Prof. Luc Tappy, Department of Physiology

Fructose is a physiological nutrient which, when consumed in excess, may have adverse metabolic effects, mainly in the liver (hepatic insulin resistance and fat storage). There is also concern that exogenous or endogenously produced fructose may be directly metabolized in extrasplanchnic cells in which it may exert adverse metabolic effects