news 2021
Transposons are foreign DNA elements capable of random insertion into the genome, an event that can be very dangerous for a cell. Their activity must be silenced to maintain genomic integrity, which is primarily achieved by H3K9me3-mediated repression. Researchers from the Gasser group identified two parallel pathways that are essential for H3K9me3- mediated transcriptional repression and thus for protecting the genome from toxic transposon activation.
Scientists have carried out the first comprehensive study of how genes in the liver perform their metabolic functions in both space and time of day. Monitoring almost 5000 genes at the level of the individual cell across a 24-hour period, the researchers have modelled how the circadian clock and liver functions crosstalk throughout the day in sync with the feeding-fasting cycle.
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Scientists at EPFL have used a snap-freezing method to reveal the true structure of the connections that join neurons together in the adult brain. Most synaptic connections in the adult brain are situated on dendritic spines; small, micrometer-long, protrusions extending from the neurons' surface. The spines' exact size and shape determine how well signals are passed from one neuron to another.
Oxygen levels in the ancient oceans were surprisingly resilient to climate change, new research suggests. An international team of scientists led by ETH Zurich used geological samples to estimate ocean oxygen during a period of global warming 56 million years ago - and found limited expansion of seafloor anoxia (absence of oxygen).
Transposons are foreign DNA elements capable of random insertion into the genome, an event that can be very dangerous for a cell. Their activity must be silenced to maintain genomic integrity, which is primarily achieved by H3K9me3-mediated repression. Researchers from the Gasser group identified two parallel pathways that are essential for H3K9me3- mediated transcriptional repression and thus for protecting the genome from toxic transposon activation.
ETH Zurich researchers conducted an experiment to investigate the initial steps in the formation of aerosols. Their findings are now aiding efforts to better understand and model that process - for example, the formation of clouds in the atmosphere. Aerosols are suspensions of fine solid particles or liquid droplets in a gas.
Scientists have carried out the first comprehensive study of how genes in the liver perform their metabolic functions in both space and time of day. Monitoring almost 5000 genes at the level of the individual cell across a 24-hour period, the researchers have modelled how the circadian clock and liver functions crosstalk throughout the day in sync with the feeding-fasting cycle.
Robotics researchers at the University of Zurich show how onboard cameras can be used to keep damaged quadcopters in the air and flying stably - even without GPS. As anxious passengers are often reassured, commercial aircrafts can easily continue to fly even if one of the engines stops working. But for drones with four propellers - also known as quadcopters - the failure of one motor is a bigger problem.
They emit must be systematically stored underground. This is the most economical of various approaches that ETH researchers have compared in detail. It is politically agreed and necessary for climate protection reasons that our entire economy becomes climate-neutral in the coming decades - and that applies to air travel, too.
Optimised on-farm grain storage boosts food security in sub-Saharan Africa, as an ETH study in Kenya during the COVID-19 pandemic shows. As the end of the lean season approaches, things get tricky for many smallholder farmers in sub-Saharan Africa. It's the time of year between harvests - the last one was a long time ago, but the next one is not yet due.
A research team at the University of Basel has discovered immune cells resident in the lungs that persist long after a bout of flu. Experiments with mice have shown that these helper cells improve the immune response to reinfection by a different strain of the flu virus. The discovery could yield approaches to developing longer-lasting vaccinations against quickly-mutating viruses.
To perform calculations, quantum computers need qubits to act as elementary building blocks that process and store information. Now, physicists have produced a new type of qubit that can be switched from a stable idle mode to a fast calculation mode. The concept would also allow a large number of qubits to be combined into a powerful quantum computer, as researchers from the University of Basel and TU Eindhoven have reported in the journal -Nature Nanotechnology-.
An international team of scientists have developed a photonic processor that uses rays of light inside silicon chips to process information much faster than conventional electronic chips. The exponential growth of data traffic in our digital age poses some real challenges on processing power. And with the advent of machine learning and AI in, for example, self-driving vehicles and speech recognition, the upward trend is set to continue.
A study on shows that goats like to earn a reward by 'working' for it, even if they can get the same reward without making any effort. This finding could benefit humane husbandry. Goats respond positively to challenges rather than just turning away. In a project funded jointly by the Swiss National Science Foundation (SNSF) and the German Research Foundation (DFG), two breeding lines - dairy goats and dwarf goats - were offered a choice of two types of reward.
Transmitting sensory signals from prostheses to the nervous system helps leg amputees to perceive prosthesis as part of their body. While amputees generally perceive their prostheses as heavy, this feedback helps them to perceive the prostheses as significantly lighter, ETH researchers have shown. Leg amputees are often not satisfied with their prosthesis, even though the sophisticated prostheses are becoming available.
A study performed in Ticino in Spring 2020, on data of SARS-CoV-2 serological tests run on healthcare workers, shows that COVID-19 antibodies are detectable in up to 10% of the participants. Such a result are comparable with the ones of the Corona Immunitas study conducted on the Ticino population. More importantly, it shows that healthcare workers with exposure to COVID-19 patients have only a slightly higher absolute risk of seropositivity than those without, suggesting that the use of protective measures in hospitals aiming at reducing nosocomial viral transmission are effective.
The Covid-19 pandemic is impacting people's mental health. But what helps and hinders people in getting through a lockdown? A new study led by researchers at the University of Basel addressed this question using data from 78 countries across the world. The results hint at the pivots and hinges on which the individual's psyche rests in the pandemic.
Researchers have created a database of over 3,000 primary and secondary packaging items from the range of the retailer Denner as a basis for ensuring more environmentally friendly packaging. The presents are unwrapped, the takeaway is eaten and the latest online order has arrived - and now there is packaging everywhere.
Revealing details of the internal structure of 'mini-brains' could help accelerate drug studies and may offer alternatives to some animal testing Geneva, Switzerland, 7 January 2021 - 'Mini-brains' are pin-head sized collections of several different types of human brain cell. They are used as a tool, allowing scientists to learn about how the brain develops, study disease and test new medicines.
The nationwide study published today was initiated by Inselspital, Bern University Hospital with the collaboration of the University of Bern and has established for the first time: severe Covid-19 can result in prolonged impairment of oxygen uptake in the lungs even after four months. Long-term monitoring and treatment of these patients is urgent and important.
Each year, around 130 kilograms of mercury flow into Swiss wastewater treatment plants, which filter out the lion's share from the waste water. This is shown by a survey of almost thirty wastewater treatment plants conducted by the Swiss Federal Institute of Aquatic Science and Technology (Eawag) and the Federal Office for the Environment (FOEN).
Researchers have demonstrated that every population can protect itself against a broad range of viruses thanks to the two most diverse HLA immune genes in humans. Do populations from different geographic regions have the same potential for defending themselves against pathogens and against viruses in particular? An analysis of human genomes, especially the HLA genes responsible for the so-called "adaptive" immune system, provide some possible answers to this question.
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