Pharmacology - May 16
Novartis data at ASCO and EHA demonstrate novel approaches to reimagining medicine in cancer and serious blood disorders
Novartis data at ASCO and EHA demonstrate novel approaches to reimagining medicine in cancer and serious blood disorders
Health - May 16
Roche’s personalised medicine entrectinib shrank tumours harbouring NTRK, ROS1 or ALK gene fusions in children and adolescents
Roche’s personalised medicine entrectinib shrank tumours harbouring NTRK, ROS1 or ALK gene fusions in children and adolescents
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Health - 17.05.2019
Health - Transport - 16.05.2019 
Particles from aircraft engines affect airways
In a unique experimental setup, Swiss researchers have investigated the effect of exhaust particles from aircraft turbine engines on human lung cells. The cells reacted most strongly to particles emitted during ground idling. The study also showed that the cytotoxic effect is only to some extent comparable to that of particles from gasoline and diesel engines.
Health - Environment - 15.05.2019 
How your clothes influence the air you breathe
Researchers have taken a critical look at how much we really know about our exposure to particles and chemicals transported by our clothing. His study concludes that further research is needed and opens up new areas of investigation. There is growing evidence that our clothing exposes us to particles and chemicals on a daily basis - and that this exposure could carry significant health risks.
Life Sciences - Health - 14.05.2019 
Relay station in the brain controls our movements
The relay station of the brain, the substantia nigra consists of different types of nerve cells and is responsible for controlling the execution of diverse movements. Researchers at the University of Basel's Biozentrum have now characterized two of these cell populations more precisely and has been able to assign an exact function to each of them.
Health - Environment - 13.05.2019 
Daily doses of vitamin D are unreachable during Swiss winter
A study funded by the SNSF shows that in winter, weak sunlight prevents the Swiss population from producing sufficient levels of vitamin D. Too much sun increases the risk of skin cancer. But moderate exposure is required to produce vitamin D. This substance is essential for bone health and may also play a role in preventing respiratory infections, autoimmune diseases and certain types of cancer.
Health - Life Sciences - 09.05.2019 
Cancer cells can communicate over longer distances within the body
EPFL researchers have discovered that cancer cells use exosomes to communicate with each other and send information through the bloodstream. This breakthrough opens up new possibilities for the use of cancer immunotherapy techniques. "It was a huge surprise, we didn't expect to find so many melanoma cancer cell markers in blood exosomes," explains Hubert Girault, who heads up the Laboratory of Physical and Analytical Electrochemistry at EPFL Valais Wallis.
Health - Life Sciences - 06.05.2019 
A barrier that keeps cancer at bay
Scientists at EPFL have discovered a biological "barrier" that prevents cancer cells from forming new tumors and more importantly, from metastasizing. The study examines pancreatic neuroendocrine tumors and breast cancer. Activins are proteins involved in a number of important biological functions, including the regulation of the menstrual cycle, cell proliferation, differentiation, apoptosis, metabolism, homeostasis, immune response, wound repair, and endocrine function.
Life Sciences - Health - 02.05.2019 
A model to decipher the complexity of gene regulation
Scientist at the Universities of Geneva and Lausanne, Switzerland, designed a framework to analyse gene regulation, and offer a model to better understand the role of the non-coding portion of the genome in disease risk. More than genes themselves, how, where and when they are expressed determine our biological traits - our phenotypes.
Health - Psychology - 29.04.2019
Health - Pharmacology - 26.04.2019 
Individual nutrition shows benefits in hospital patients
Individualized nutrition not only causes hospital patients to consume more protein and calories, but also improves clinical treatment outcomes. This has been demonstrated in a study by researchers from the University of Basel and Aarau Cantonal Hospital in the journal The Lancet. People who struggle to eat and drink properly following an illness are at risk of consuming too little protein and energy.
Life Sciences - Health - 25.04.2019 
Intestinal organoid development mimics regeneration
Intestinal organoids are three-dimensional structures derived from a single intestinal stem cell. They are great tools for applications ranging from fundamental biology to personalized and regenerative medicine. However, despite their relevance in research, it is still unclear how a single cell can give rise to a fully formed organoid.
Health - 25.04.2019 
One in two Swiss people will have smoked weed by 2045
Three decades from now, nearly half of the Swiss population will have had some experience with cannabis use. According to a new study by the University of Zurich, the number of active users will rise as well, increasing by 50% compared to 2015 - unless the government establishes new regulations. Countries such as Canada and Uruguay have introduced new paradigms when it comes to regulating the sale and consumption of cannabis.
Health - Pharmacology - 23.04.2019 
Simple and Fast Method for Radiolabelling Antibodies against Breast Cancer
Radioactive antibodies that target cancer cells are used for medical diagnostics with PET imaging or for targeted radioimmunotherapy. Researchers from the University of Zurich have created a new method for radiolabelling antibodies using UV light. In less than 15 minutes, the proteins are ready-to-use for cancer imaging or therapy.
Health - Pharmacology - 15.04.2019
Health - Pharmacology - 11.04.2019 
The way people walk says a lot about how healthy they are
Gait characteristics are sometimes regarded as the sixth vital sign in humans. They serve as a valuable indicator of a person's health, particularly in older adults - so why not measure them? A team of EPFL researchers is taking part in a major European project to design a device that can assess a person's gait more accurately.
Life Sciences - Health - 08.04.2019 
Deep Brain Stimulation Against Movement and Psychiatric Disorders
A new paper published suggests that recent advances in deep brain stimulation (DBS) for Parkinson disease could lead to treatments for conditions such as obsessive-compulsive disorder (OCD), Gilles de la Tourette syndrome and depression. The authors of the paper argue that bi-directional electrodes, which can both stimulate and record from deep brain structures - known as closed-loop DBS, could have applications beyond Parkinson disease.
Health - 02.04.2019
Physics - Health - 02.04.2019 
Harnessing photonics for at-home disease detection
With nothing more than a photonic chip and an ordinary camera, EPFL researchers have managed to count biomolecules one by one in a small sample and determine their position. Their tiny device - a marriage of optics and smart image analysis - is even able to detect a graphene sheet only a single atom thick.
Life Sciences - Health - 28.03.2019 
Crime Scene Schizophrenia - 30 Genes under suspicion
A research group has identified 30 genes associated with schizophrenia. The team was able to show which pathological changes in the brain and behavioral abnormalities are triggered by these genes. The results of the study have now been published in "Cell". The research team of the Biozentrum, University of Basel investigated a total of 132 genes associated with schizophrenia.
Health - Pharmacology - 28.03.2019 
Breast cancer: the promises of old recipes
Researchers from UNIGE and UNIL demonstrate the efficacy of a well-known antibiotic in treating a particularly fatal form of breast cancer, offering hope for targeted therapy. Of the three major subtypes of breast cancer, the «triple negative» is the most lethal: half of all breast cancer deaths are attributed to it, whereas it accounts for only about 15% of incidences of breast cancer.
Health
Results 1 - 20 of 505.
New Findings on Malaria Vaccine
Protection by the malaria vaccine RTS,S is not only a matter of antibody quantity but also of quality. These are the findings of a study led by the Barcelona Institute for Global Health (ISGlobal) in collaboration with Swiss TPH and other partners. The research show for the first time that the higher the avidity of antibodies induced by the RTS,S vaccine, the greater the protection.
Protection by the malaria vaccine RTS,S is not only a matter of antibody quantity but also of quality. These are the findings of a study led by the Barcelona Institute for Global Health (ISGlobal) in collaboration with Swiss TPH and other partners. The research show for the first time that the higher the avidity of antibodies induced by the RTS,S vaccine, the greater the protection.
In a unique experimental setup, Swiss researchers have investigated the effect of exhaust particles from aircraft turbine engines on human lung cells. The cells reacted most strongly to particles emitted during ground idling. The study also showed that the cytotoxic effect is only to some extent comparable to that of particles from gasoline and diesel engines.
Researchers have taken a critical look at how much we really know about our exposure to particles and chemicals transported by our clothing. His study concludes that further research is needed and opens up new areas of investigation. There is growing evidence that our clothing exposes us to particles and chemicals on a daily basis - and that this exposure could carry significant health risks.
The relay station of the brain, the substantia nigra consists of different types of nerve cells and is responsible for controlling the execution of diverse movements. Researchers at the University of Basel's Biozentrum have now characterized two of these cell populations more precisely and has been able to assign an exact function to each of them.
A study funded by the SNSF shows that in winter, weak sunlight prevents the Swiss population from producing sufficient levels of vitamin D. Too much sun increases the risk of skin cancer. But moderate exposure is required to produce vitamin D. This substance is essential for bone health and may also play a role in preventing respiratory infections, autoimmune diseases and certain types of cancer.
EPFL researchers have discovered that cancer cells use exosomes to communicate with each other and send information through the bloodstream. This breakthrough opens up new possibilities for the use of cancer immunotherapy techniques. "It was a huge surprise, we didn't expect to find so many melanoma cancer cell markers in blood exosomes," explains Hubert Girault, who heads up the Laboratory of Physical and Analytical Electrochemistry at EPFL Valais Wallis.
Scientists at EPFL have discovered a biological "barrier" that prevents cancer cells from forming new tumors and more importantly, from metastasizing. The study examines pancreatic neuroendocrine tumors and breast cancer. Activins are proteins involved in a number of important biological functions, including the regulation of the menstrual cycle, cell proliferation, differentiation, apoptosis, metabolism, homeostasis, immune response, wound repair, and endocrine function.
Scientist at the Universities of Geneva and Lausanne, Switzerland, designed a framework to analyse gene regulation, and offer a model to better understand the role of the non-coding portion of the genome in disease risk. More than genes themselves, how, where and when they are expressed determine our biological traits - our phenotypes.
Susceptibility to Disease Develops during Childhood
Traumatized children and children who develop multiple allergies tend to suffer in adulthood from chronic inflammatory diseases and psychiatric disorders. Researchers at the Universities of Zurich and Lausanne have demonstrated this in a study in which they identified five classes of early immune-system programming.
Traumatized children and children who develop multiple allergies tend to suffer in adulthood from chronic inflammatory diseases and psychiatric disorders. Researchers at the Universities of Zurich and Lausanne have demonstrated this in a study in which they identified five classes of early immune-system programming.
Individualized nutrition not only causes hospital patients to consume more protein and calories, but also improves clinical treatment outcomes. This has been demonstrated in a study by researchers from the University of Basel and Aarau Cantonal Hospital in the journal The Lancet. People who struggle to eat and drink properly following an illness are at risk of consuming too little protein and energy.
Intestinal organoids are three-dimensional structures derived from a single intestinal stem cell. They are great tools for applications ranging from fundamental biology to personalized and regenerative medicine. However, despite their relevance in research, it is still unclear how a single cell can give rise to a fully formed organoid.
Three decades from now, nearly half of the Swiss population will have had some experience with cannabis use. According to a new study by the University of Zurich, the number of active users will rise as well, increasing by 50% compared to 2015 - unless the government establishes new regulations. Countries such as Canada and Uruguay have introduced new paradigms when it comes to regulating the sale and consumption of cannabis.
Radioactive antibodies that target cancer cells are used for medical diagnostics with PET imaging or for targeted radioimmunotherapy. Researchers from the University of Zurich have created a new method for radiolabelling antibodies using UV light. In less than 15 minutes, the proteins are ready-to-use for cancer imaging or therapy.
Precise Decoding of Breast Cancer Cells Creates New Option for Treatment
Researchers at the University of Zurich and from IBM Research have investigated the varying composition of cancer and immune cells in over one hundred breast tumors. They've found that aggressive tumors are often dominated by a single type of tumor cell. If certain immune cells are present as well, an immune therapy could be successful for a specific group of breast cancer patients.
Researchers at the University of Zurich and from IBM Research have investigated the varying composition of cancer and immune cells in over one hundred breast tumors. They've found that aggressive tumors are often dominated by a single type of tumor cell. If certain immune cells are present as well, an immune therapy could be successful for a specific group of breast cancer patients.
Gait characteristics are sometimes regarded as the sixth vital sign in humans. They serve as a valuable indicator of a person's health, particularly in older adults - so why not measure them? A team of EPFL researchers is taking part in a major European project to design a device that can assess a person's gait more accurately.
A new paper published suggests that recent advances in deep brain stimulation (DBS) for Parkinson disease could lead to treatments for conditions such as obsessive-compulsive disorder (OCD), Gilles de la Tourette syndrome and depression. The authors of the paper argue that bi-directional electrodes, which can both stimulate and record from deep brain structures - known as closed-loop DBS, could have applications beyond Parkinson disease.
Nestlé Health Science set to use anti-aging compound
Amazentis, an EPFL spin-off based in Innovation Park, announced today that it is entering into a strategic partnership with Nestlé Health Science. The startup plans to develop products based on urolithin A, a promising anti-aging compound. The Fountain of Youth is still the stuff of legend, but the anti-aging compound urolithin A is now one step closer to the market.
Amazentis, an EPFL spin-off based in Innovation Park, announced today that it is entering into a strategic partnership with Nestlé Health Science. The startup plans to develop products based on urolithin A, a promising anti-aging compound. The Fountain of Youth is still the stuff of legend, but the anti-aging compound urolithin A is now one step closer to the market.
With nothing more than a photonic chip and an ordinary camera, EPFL researchers have managed to count biomolecules one by one in a small sample and determine their position. Their tiny device - a marriage of optics and smart image analysis - is even able to detect a graphene sheet only a single atom thick.
A research group has identified 30 genes associated with schizophrenia. The team was able to show which pathological changes in the brain and behavioral abnormalities are triggered by these genes. The results of the study have now been published in "Cell". The research team of the Biozentrum, University of Basel investigated a total of 132 genes associated with schizophrenia.
Researchers from UNIGE and UNIL demonstrate the efficacy of a well-known antibiotic in treating a particularly fatal form of breast cancer, offering hope for targeted therapy. Of the three major subtypes of breast cancer, the «triple negative» is the most lethal: half of all breast cancer deaths are attributed to it, whereas it accounts for only about 15% of incidences of breast cancer.
Pharmacology - May 16
Novartis data at ASCO and EHA demonstrate novel approaches to reimagining medicine in cancer and serious blood disorders
Novartis data at ASCO and EHA demonstrate novel approaches to reimagining medicine in cancer and serious blood disorders
Health - May 16
Roche’s personalised medicine entrectinib shrank tumours harbouring NTRK, ROS1 or ALK gene fusions in children and adolescents
Roche’s personalised medicine entrectinib shrank tumours harbouring NTRK, ROS1 or ALK gene fusions in children and adolescents