Pharmacology - 07:01
FDA grants Breakthrough Therapy Designation for Roche’s Gazyva (obinutuzumab) in Lupus Nephritis
FDA grants Breakthrough Therapy Designation for Roche’s Gazyva (obinutuzumab) in Lupus Nephritis
Pharmacology - Sep 17
Novartis Cosentyx positive 16-week PREVENT results advance potential new indication for patients with axial spondyloarthritis
Novartis Cosentyx positive 16-week PREVENT results advance potential new indication for patients with axial spondyloarthritis
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Life Sciences - Health - 19:03 
The path of breast-to-brain cancer metastasis
Scientists at EPFL's Swiss Institute for Experimental Cancer Research and University of Bern have discovered a signaling pathway that breast tumors exploit to metastasize to the brain. In 2018, breast cancer was the most common cancer in women worldwide, accounting for about a quarter of all reported cancers.
Health - Life Sciences - 19:02 
The path of breast-to-brain cancer metastasis
Scientists at EPFL's Swiss Institute for Experimental Cancer Research have discovered a signaling pathway that breast tumors exploit to metastasize to the brain. Image: Breast cancer cells (blue) associate with glutamate-secreting neurons (red) to stimulate NMDA receptor-mediated signaling (green) of tumor growth (STED super-resolution microscopy). In 2018, breast cancer was the most common cancer in women worldwide, accounting for about a quarter of all reported cancers.
Pharmacology - Health - 16:31
Health - Pharmacology - 11:32 
AI-based prognosis in intensive care: decision-relevant patterns identified in EEG of coma patients
A reliable prognosis for coma patients in the intensive care unit is crucial. Improved transparency will boost the use of Artificial Intelligence (AI) to support end-of-life decisions. For the first time, a research team has succeeded in identifying specific patterns in Electro-Encephalogram (EEG) analyses that the deep-learning network uses for making prognosis decisions.
Health - Mathematics - 16.09.2019 
Jeanne Calment was indeed the oldest human being
By combining epidemiology, mathematical modelling and historical investigation, researchers in Geneva, Switzerland and France confirm Jeanne Calment's exceptional longevity, invalidating the conspiracy theories surrounding her. Jeanne Calment, who passed away in 1997 at 122 years and 165 days, still is today the human being who had the longest life.
Health - 12.09.2019 
A high-precision instrument for ophthalmologists
EPFL scientists have helped develop a microscopic glass device that doctors could use to inject medicine into retinal veins with unprecedented accuracy. Their instrument meets an important need in eye surgery, delivering exceptional stability and precision. A team of researchers presented a breakthrough device for eye surgery at EPFL Neuchâtel's Research Day on 11 September.
Health - Life Sciences - 12.09.2019 
Type 2 diabetes is not just about insulin
By showing that the liver can produce glucose autonomously, researchers at UNIGE explain how type 2 diabetes can develop in overweight people even without insulin resistance. In Switzerland, more than 400,000 people suffer from type 2 diabetes, a serious metabolic disorder that is constantly increasing.
Life Sciences - Health - 11.09.2019 
Advanced breeding paves the way for disease-resistant beans
ETH researchers are involved in the development and implementation of a method to efficiently breed for disease-resistant beans in different regions of the world. Their work will help to improve the livelihood and food security of smallholders in developing countries. For many people in Africa and Latin America, beans are an important staple.
Pharmacology - Health - 10.09.2019 
Multiple sclerosis therapy: scientists identify the Achilles’ heel of a therapeutic antibody and find a solution to avoid the problem
An international research team led by the Institute for Research in Biomedicine, affiliated to the Università della Svizzera italiana, has discovered why some patients with multiple sclerosis make an immune reaction that curtails the effectiveness of natalizumab, a therapeutic antibody used for the treatment of the disease and used this information to engineer a new version of the antibody that avoids this problem.
Life Sciences - Health - 09.09.2019
Life Sciences - Health - 09.09.2019 
The birth of vision, from the retina to the brain
By decoding the genetic mechanisms that control the neurons of the visual system, researchers at UNIGE are unveiling the first steps in the construction of vision, paving the way for regenerative eye medicine.
Life Sciences - Health - 05.09.2019 
Resistance can spread even without the use of antibiotics
Antibiotic resistance does not spread only where and when antibiotics are used in large quantities, ETH researchers conclude from laboratory experiments. Reducing antibiotic use alone is therefore not sufficient to curtail resistance, and should be done in conjunction with measures to prevent infection with resistant germs.
Life Sciences - Health - 29.08.2019 
Preventing the onset of schizophrenia in mouse model
Although predisposing processes occur earlier, schizophrenia breaks out at young adulthood, suggesting it might involve a pathological transition during late brain development in predisposed individuals. Using a genetic mouse model of schizophrenia, researchers from the Caroni group at the FMI showed that, like in patients, characteristic network and cognitive deficits only emerge in adult mice.
Life Sciences - Health - 28.08.2019 
Brain stem cells have a good memory
By successfully rejuvenating brain progenitor cells, researchers at UNIGE reveal an unsuspected role of the environment in setting cellular properties. The cerebral cortex acts as the control centre of our cognitive processes. During embryogenesis, dozens of types of neurons with distinct functions come together to form the circuits that drive our thoughts and actions.
Health - 23.08.2019 
Bioprinting complex living tissue in just a few seconds
Researchers from EPFL and the University Medical Center Utrecht in the Netherlands have developed an extremely fast optical method for sculpting complex shapes in stem-cell-laden hydrogels and then vascularizing the resulting tissue. Their groundbreaking technique stands to change the field of tissue engineering.
Pharmacology - Health - 22.08.2019 
Preventing tumour metastasis
Researchers at the Paul Scherrer Institute, together with colleagues from the pharmaceutical company F. Hoffmann-La Roche AG, have taken an important step towards the development of an agent against the metastasis of certain cancers. Using the Swiss Light Source, they deciphered the structure of a receptor that plays a crucial role in the migration of cancer cells.
Life Sciences - Health - 19.08.2019 
Optic nerve stimulation to aid the blind
EPFL scientists are investigating new ways to provide visual signals to the blind by directly stimulating the optic nerve. Their preliminary study on animals uses a new type of neural electrode and provides distinct signals. Scientists from EPFL in Switzerland and Scuola Superiore Sant'Anna in Italy are developing technology for the blind that bypasses the eyeball entirely and sends messages to the brain.
Life Sciences - Health - 19.08.2019 
When liver disease affects the brain
Scientists have demonstrated how chronic liver diseases cause molecular changes in the brain. They carried out their research using the 9.4 Tesla high-magnetic-field MRI machine at the Center for Biomedical Imaging (CIBM) at EPFL. The liver plays a vital role as a filter in the human body.
Health - Life Sciences - 19.08.2019 
When a diseased liver disrupts the brain
Researchers from UNIGE, CHUV, EPFL, CIBM, HUG and UNIL have demonstrated how chronic liver diseases cause molecular changes in the brain. The liver plays a vital role as a filter in the human body.
Life Sciences - Health - 19.08.2019 
Smart interaction between proteins
Very little was known till now about DNA repair by homologous recombination, which is fundamental for human health. Now an ETH research group has for the first time isolated and studied all the key proteins involved in this process, laying the foundation for investigating many diseases. Within our body, the process of cell division is constantly creating new cells to replace old or damaged ones.
Health
Results 1 - 20 of 561.
Scientists at EPFL's Swiss Institute for Experimental Cancer Research and University of Bern have discovered a signaling pathway that breast tumors exploit to metastasize to the brain. In 2018, breast cancer was the most common cancer in women worldwide, accounting for about a quarter of all reported cancers.
Scientists at EPFL's Swiss Institute for Experimental Cancer Research have discovered a signaling pathway that breast tumors exploit to metastasize to the brain. Image: Breast cancer cells (blue) associate with glutamate-secreting neurons (red) to stimulate NMDA receptor-mediated signaling (green) of tumor growth (STED super-resolution microscopy). In 2018, breast cancer was the most common cancer in women worldwide, accounting for about a quarter of all reported cancers.
Positive results from Novartis five-year VERIFY study in type 2 diabetes demonstrate long-term clinical benefits of early combination treatment with Galvus and metformin
Early combination treatment strategy with vildagliptin (Galvus ) and metformin was superior to standard of care in newly diagnosed type 2 diabetes patients , The landmark VERIFY study is the first to investigate the long-term clinical benefits of this early combination strategy in type 2 diabetes (T2DM) Novartis is committed to optimizing patient management of T2DM to achieve better glycemic control and favorable long-term clinical outcomes
Early combination treatment strategy with vildagliptin (Galvus ) and metformin was superior to standard of care in newly diagnosed type 2 diabetes patients , The landmark VERIFY study is the first to investigate the long-term clinical benefits of this early combination strategy in type 2 diabetes (T2DM) Novartis is committed to optimizing patient management of T2DM to achieve better glycemic control and favorable long-term clinical outcomes
A reliable prognosis for coma patients in the intensive care unit is crucial. Improved transparency will boost the use of Artificial Intelligence (AI) to support end-of-life decisions. For the first time, a research team has succeeded in identifying specific patterns in Electro-Encephalogram (EEG) analyses that the deep-learning network uses for making prognosis decisions.
By combining epidemiology, mathematical modelling and historical investigation, researchers in Geneva, Switzerland and France confirm Jeanne Calment's exceptional longevity, invalidating the conspiracy theories surrounding her. Jeanne Calment, who passed away in 1997 at 122 years and 165 days, still is today the human being who had the longest life.
EPFL scientists have helped develop a microscopic glass device that doctors could use to inject medicine into retinal veins with unprecedented accuracy. Their instrument meets an important need in eye surgery, delivering exceptional stability and precision. A team of researchers presented a breakthrough device for eye surgery at EPFL Neuchâtel's Research Day on 11 September.
By showing that the liver can produce glucose autonomously, researchers at UNIGE explain how type 2 diabetes can develop in overweight people even without insulin resistance. In Switzerland, more than 400,000 people suffer from type 2 diabetes, a serious metabolic disorder that is constantly increasing.
ETH researchers are involved in the development and implementation of a method to efficiently breed for disease-resistant beans in different regions of the world. Their work will help to improve the livelihood and food security of smallholders in developing countries. For many people in Africa and Latin America, beans are an important staple.
An international research team led by the Institute for Research in Biomedicine, affiliated to the Università della Svizzera italiana, has discovered why some patients with multiple sclerosis make an immune reaction that curtails the effectiveness of natalizumab, a therapeutic antibody used for the treatment of the disease and used this information to engineer a new version of the antibody that avoids this problem.
Feeling legs again improves amputees’ health
Two volunteers are the first above-knee amputees in the world to feel their prosthetic foot and knee in real time. Their bionic prosthesis, which was developed by an international team of researchers, features sensors that connect to residual nerves in the thigh. The resulting neurofeedback greatly reduces physical and mental strain for users of the prosthesis.
Two volunteers are the first above-knee amputees in the world to feel their prosthetic foot and knee in real time. Their bionic prosthesis, which was developed by an international team of researchers, features sensors that connect to residual nerves in the thigh. The resulting neurofeedback greatly reduces physical and mental strain for users of the prosthesis.
By decoding the genetic mechanisms that control the neurons of the visual system, researchers at UNIGE are unveiling the first steps in the construction of vision, paving the way for regenerative eye medicine.
Antibiotic resistance does not spread only where and when antibiotics are used in large quantities, ETH researchers conclude from laboratory experiments. Reducing antibiotic use alone is therefore not sufficient to curtail resistance, and should be done in conjunction with measures to prevent infection with resistant germs.
Although predisposing processes occur earlier, schizophrenia breaks out at young adulthood, suggesting it might involve a pathological transition during late brain development in predisposed individuals. Using a genetic mouse model of schizophrenia, researchers from the Caroni group at the FMI showed that, like in patients, characteristic network and cognitive deficits only emerge in adult mice.
By successfully rejuvenating brain progenitor cells, researchers at UNIGE reveal an unsuspected role of the environment in setting cellular properties. The cerebral cortex acts as the control centre of our cognitive processes. During embryogenesis, dozens of types of neurons with distinct functions come together to form the circuits that drive our thoughts and actions.
Researchers from EPFL and the University Medical Center Utrecht in the Netherlands have developed an extremely fast optical method for sculpting complex shapes in stem-cell-laden hydrogels and then vascularizing the resulting tissue. Their groundbreaking technique stands to change the field of tissue engineering.
Researchers at the Paul Scherrer Institute, together with colleagues from the pharmaceutical company F. Hoffmann-La Roche AG, have taken an important step towards the development of an agent against the metastasis of certain cancers. Using the Swiss Light Source, they deciphered the structure of a receptor that plays a crucial role in the migration of cancer cells.
EPFL scientists are investigating new ways to provide visual signals to the blind by directly stimulating the optic nerve. Their preliminary study on animals uses a new type of neural electrode and provides distinct signals. Scientists from EPFL in Switzerland and Scuola Superiore Sant'Anna in Italy are developing technology for the blind that bypasses the eyeball entirely and sends messages to the brain.
Scientists have demonstrated how chronic liver diseases cause molecular changes in the brain. They carried out their research using the 9.4 Tesla high-magnetic-field MRI machine at the Center for Biomedical Imaging (CIBM) at EPFL. The liver plays a vital role as a filter in the human body.
Researchers from UNIGE, CHUV, EPFL, CIBM, HUG and UNIL have demonstrated how chronic liver diseases cause molecular changes in the brain. The liver plays a vital role as a filter in the human body.
Very little was known till now about DNA repair by homologous recombination, which is fundamental for human health. Now an ETH research group has for the first time isolated and studied all the key proteins involved in this process, laying the foundation for investigating many diseases. Within our body, the process of cell division is constantly creating new cells to replace old or damaged ones.
Pharmacology - 07:01
FDA grants Breakthrough Therapy Designation for Roche’s Gazyva (obinutuzumab) in Lupus Nephritis
FDA grants Breakthrough Therapy Designation for Roche’s Gazyva (obinutuzumab) in Lupus Nephritis
Pharmacology - Sep 17
Novartis Cosentyx positive 16-week PREVENT results advance potential new indication for patients with axial spondyloarthritis
Novartis Cosentyx positive 16-week PREVENT results advance potential new indication for patients with axial spondyloarthritis