news

« BACK

Pharmacology



Results 1 - 20 of 276.
1 2 3 4 5 ... 14 Next »


Pharmacology - Health - 22.10.2021
Mechanism Behind Ineffective Psoriasis Drugs Identified
Mechanism Behind Ineffective Psoriasis Drugs Identified
Interleukin-12 - a messenger molecule of immune cells - was long considered to trigger the development of psoriasis. Now, researchers at the University of Zurich have shown that interleukin-12 does not actually cause the skin disease but protects against it. This also explains why common psoriasis drugs that block the messenger show insufficient treatment efficacy.

Health - Pharmacology - 20.10.2021
Towards Precision Medicine for Dialysis Patients
Towards Precision Medicine for Dialysis Patients
A common gene variant for the protein Aquaporin-1 lowers the amount of water channels in the cell membranes. This reduces water transport and leads to a higher risk of death in patients with kidney failure treated with peritoneal dialysis. In such cases, specific osmotic solutions should be used, as an international research team led by the University of Zurich has shown.

Pharmacology - 14.10.2021
New proteins enable scientists to control cell activities
New proteins enable scientists to control cell activities
Scientists have developed new controlled proteins and used to switch cellular activities on and off like a light bulb. Sailan Shui, a doctoral assistant at EPFL's Laboratory of Protein Design and Immunoengineering, enjoys playing with proteins, activating and deactivating them as she wishes, as if light switches that can be turned on and off.

Health - Pharmacology - 12.10.2021
Highly potent antibody against SARS-CoV-2
Highly potent antibody against SARS-CoV-2
Scientists at Lausanne University Hospital (CHUV) and EPFL have discovered a highly potent monoclonal antibody that targets the SARS-CoV-2 spike protein and is effective at neutralizing all variants of concern identified to date, including the delta variant. Their findings are published in the prestigious journal Cell Reports.

Health - Pharmacology - 07.10.2021
Financial rewards lead to higher vaccination uptake
Modest financial rewards can help increase COVID-19 vaccination rates. This is the conclusion of an international study co-lead by Swiss universities, based on data from Sweden. Despite countless appeals from politicians and scientists, stagnating vaccination rates hamper the containment of coronavirus.

Pharmacology - Life Sciences - 01.10.2021
A tool to interrogate a new class of drugs
Reactive electrophilic drugs like Tecfidera, approved for the treatment of relapsing multiple sclerosis, show a lot of potential but are also mystery. Their effects are notoriously difficult to study, which hampers progress testing and approving them. scientists have now used an innovative chemical method to uncover the biological mechanisms of Tecfidera, providing a powerful tool for exploring other reactive electrophilic drugs.

Life Sciences - Pharmacology - 30.09.2021
Relieving pain by mapping its biological signatures
Relieving pain by mapping its biological signatures
Researchers at the University of Geneva and the Clinique romande de réadaptation in Sion have mapped the biomarkers of different types of pain to categorise and better treat them in the future. Many people are confronted with chronic pain that can last for months or even years. How to best treat chronic pain? First, pain must be categorized for the right treatment to be prescribed.

Health - Pharmacology - 28.09.2021
Antidepressants Inhibit Cancer Growth in Mice
Classic antidepressants could help improve modern cancer treatments. They slowed the growth of pancreatic and colon cancers in mice, and when combined with immunotherapy, they even stopped the cancer growth long-term. In some cases the tumors disappeared completely, researchers at UZH and USZ have found.

Pharmacology - Health - 28.09.2021
Watching and analyzing T cells attack cancer cells in real time
Watching and analyzing T cells attack cancer cells in real time
A new assay developed by EPFL spin-off Nanolive opens up promising avenues of research for immuno-oncology treatments. It allows scientists to directly see and quantify how T cells find, bind, stress and kill cancer cells. Immuno-oncology is a promising new field of research that involves boosting the capacity of a patient's own immune system to attack cancer cells.

Health - Pharmacology - 28.09.2021
Decrease in mortality from rare side effect
A large-scale international study co-led by Inselspital and the University of Bern investigated the very rare adverse cerebral venous occlusion (sinus venous thrombosis) after administration of the Oxford-AstraZeneca and Janssen/Johnson&Johnson vaccines. Neither vaccine has been used in Switzerland to date.

Computer Science - Pharmacology - 20.09.2021
Augmented reality helps tackle fear of spiders
Augmented reality helps tackle fear of spiders
Researchers from the University of Basel have developed an augmented reality app for smartphones in order to help people reduce their fear of spiders. The app has already shown itself to be effective in a clinical trial, with subjects experiencing less fear of real spiders after completing just a few training units with the app at home.

Health - Pharmacology - 16.09.2021
Improving leukemia therapy with targeted treatment approaches
In chronic leukemias, blocking the overactive kinase JAK2 by a targeted therapy approach is only mitigating the patients' symptoms, but cannot truly change the course of the disease. A study by the University of Basel has shown that it may be possible to improve the therapeutic effects by additionally inhibiting a specific signaling pathway.

Pharmacology - Chemistry - 13.09.2021
New immunotherapy method turns activated specifically in tumor
New immunotherapy method turns activated specifically in tumor
Scientists have developed a chemical method for targeting the effects of cancer-fighting immunotherapy drugs only to the tumor tissue, making the drugs less toxic to the rest of the human body. Immunotherapy drugs are promising new weapons in the fight against cancer, but they are so strong that they can be toxic to the rest of the human body.

Health - Pharmacology - 01.09.2021
Nasal cartilage relieves osteoarthritis in the knee
Nasal cartilage relieves osteoarthritis in the knee
Cartilage cells from the nasal septum can not only help repair cartilage injuries in the knee - according to researchers from the University of Basel and the University Hospital Basel, they can also withstand the chronic inflammatory tissue environment in osteoarthritis and even counteract the inflammation.

Health - Pharmacology - 16.08.2021
Lung cancer: Hope for increasing immunotherapy efficacy
Lung cancer: Hope for increasing immunotherapy efficacy
A "paradox and setback" forced scientists to dig deeper when seeking a means to boost the power of immunotherapy in lung cancer. Understanding the problem - and finding the solution - has led to a promising potential therapy for some patients. Lung cancer is the leading cause of cancer-related death.

Pharmacology - Health - 12.08.2021
New database could accelerate drug repurposing for various diseases
New database could accelerate drug repurposing for various diseases
NICEdrug.ch, a new database developed by a group of researchers from EPFL, may help scientists assess potential drugs more quickly, including how they are metabolized by the body and their potential side effects. Researchers from EPFL have created a new open-access database of information on drug candidates and how they are metabolized by the body, which could help speed up the repurposing of old drugs as new treatments.

Health - Pharmacology - 03.08.2021
Breath test to determine correct treatment for epilepsy
Breath test to determine correct treatment for epilepsy
Breath instead of blood: researchers from the University of Basel have developed a new test method to measure treatment success in epilepsy patients. They hope that this will enable doctors to react more precisely when treating the disease. Epilepsy affects some 50 million people worldwide and pharmaceutical treatment of the disease is a tightrope walk, as the dose must be tailored precisely to the individual patient: "Slightly too little and it isn't effective.

Life Sciences - Pharmacology - 21.07.2021
Toxicity testing on the placenta and embryo
Toxicity testing on the placenta and embryo
Researchers at ETH Zurich have developed a cell culture test to detect substances that are directly or indirectly harmful to embryos. Based on an existing test used for developing new drugs and chemicals, the augmented version is designed to help reduce the number of animal experiments. Drugs must be safe not just for the patients; in the case of pregnant patients, drugs must also be safe for the unborn children still in the womb.

Health - Pharmacology - 15.07.2021
Why do scientific discovery take so long to reach the general public?
Why do scientific discovery take so long to reach the general public?
SUMMER SERIES: HOW SCIENCE WORKS For scientists, the path from bright idea to finished product is a long one. Prototypes must go through an extensive testing and approval process before they are ready for the market. Let's have a look. The results of scientific research can often bring considerable societal and economic benefits.

Health - Pharmacology - 15.07.2021
Why do scientific discoveries take long to reach the general public?
Why do scientific discoveries take long to reach the general public?
SUMMER SERIES: HOW SCIENCE WORKS For scientists, the path from bright idea to finished product is a long one. Prototypes must go through an extensive testing and approval process before they are ready for the market. Let's have a look. The results of scientific research can often bring considerable societal and economic benefits.
1 2 3 4 5 ... 14 Next »

This site uses cookies and analysis tools to improve the usability of the site. More information. |