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Media - 16.05.2022
Youth and information
Nearly one-third of young people in Switzerland have little to no interest in the news. Various studies show that daily world events are of secondary importance to them. They rarely use information sources and thus develop limited literacy in dealing with and processing news, which makes them more susceptible/vulnerable to misinformation.

Pharmacology - Health - 09.05.2022
Lymphomas: new model developed at the IOR against drug resistance
Lymphomas: new model developed at the IOR against drug resistance
The Lymphoma Genomics group, directed by Prof. Francesco Bertoni at the Institute of Oncology Research (IOR, affiliated to USI and member of Bios+), identified a new mechanism behind the resistance to the drug idelalisib, used in the treatment of patients with follicular lymphoma and marginal zone lymphoma.

Health - Life Sciences - 28.04.2022
Breakthroughs at IOR in the search for anti-metastatic therapies
Breakthroughs at IOR in the search for anti-metastatic therapies
The Molecular Oncology research group at USI has identified, through the use of bioinformatics and artificial intelligence, a new way to selectively identify and kill a specific type of cells involved in metastasis dissemination. The problem Metastasis, the spreading of tumor cells from a primary site to their progressive outgrowth at a distant organ, is ultimately what kills almost 90% patients with cancer.

Economics / Business - 07.03.2022
Skill, scale, and value creation in the mutual fund industry
When investors shop for mutual funds, they typically focus on performance, which is generally measured by the level of returns (compared to a given benchmark). However, far less is known about value creation, i.e. whether funds, or rather the fund managers, are capable of extracting genuine value from capital markets through their investment decisions.

Health - Mathematics - 25.02.2022
Mathematics helps AI in biomedicine
Mathematics helps AI in biomedicine
"Data is the new oil", it has often been said. Indeed, in the digital age data is the fuel that runs the engines of digital media, advanced informatics (AI, machine learning etc.) and, not least, scientific research. Nevertheless, when facing certain highly complex issues, data-driven approaches may not always be the most effective solutions.

Health - Life Sciences - 10.02.2022
IOR and IOSI gold medal in lymphomas
The New England Journal of Medicine (NEJM), the world's leading medical journal, has entrusted the lymphoma group of the Institute of Oncological Research (IOR, affiliated to USI and member of Bios+) and the Oncological Institute of Southern Switzerland (IOSI, Ente Ospedaliero Cantonale) with the task of compiling a state-of-the-art report on malignant lymphomas.

Life Sciences - Health - 03.02.2022
USI’s commitment to reducing and replacing animal testing
USI Pro-Rector for Research Prof. Patrick Gagliardini talks about USI's commitment to reduce, where possible, the use of animal experiments by replacing them with alternative models, bringing concrete examples of approaches to achieve this goal. USI has been actively involved in the Swiss 3R Competence Centre (3RCC) since its founding in 2018 and has recently renewed its commitment.

Health - Life Sciences - 10.01.2022
Novel method to track precisely prostate cancer progression
In the fight against tumours, how the key driver mutations related to disease progression and metastatic spread regulate gene expression to promote ultimately tumor progression and cancer cell adaptation to therapies have remained largely elusive. Using the gene expression fingerprint of cancer cells, researchers at the Istitute of Oncology Research (IOR, affiliated to USI Universitą della Svizzera italiana) in Bellinzona have now developed a novel method to track precisely prostate cancer progression in an unprecedented manner.

Health - Pharmacology - 10.01.2022
Reasons for rejecting the initiative to ban animal and human experimentation in Switzerland
On 13 February 2022, Swiss citizens will be asked to vote on a popular initiative calling for a complete ban on all animal and human experimentation in Switzerland. The initiative also calls for a ban, from 2024, on all new drugs and medical treatments that have been tested on animals or humans, anywhere in the world.

Physics - Astronomy / Space Science - 19.08.2021
Researchers from IRSOL and IAC solve twenty-year-old paradox in solar physics
Researchers from IRSOL and IAC solve twenty-year-old paradox in solar physics
In 1998, the journal Nature published a seminal letter concluding that a mysterious signal, which had been recently discovered analysing the polarization of sunlight, implies that the solar chromosphere (a very important layer of the solar atmosphere) is practically unmagnetised, in sharp contradiction with common wisdom.

Health - Life Sciences - 08.07.2021
A 'molecular switch' turns on the unfavorable evolution of prostate tumors
A ’molecular switch’ turns on the unfavorable evolution of prostate tumors
Researchers from the Prostate Cancer Biology laboratory, directed by Giuseppina Carbone, M.D., at the Institute of Oncology Research (IOR, affiliated to USI) in Bellinzona, have discovered an unexpected mechanism that drives the largest group of prostate tumors' evolution, the ERG fusion-positive prostate cancers.

Chemistry - 02.06.2021
Cutting-edge modelling methods from USI help unlock the secrets of porous material
Cutting-edge modelling methods from USI help unlock the secrets of porous material
Most materials have a seemingly smooth surface, but under high magnification, they reveal to be full of tiny holes or pores. Zeolites, in particular, have pores in different sizes that allow them to be used in a range of different applications like catalysis, the branch of chemistry that studies how to accelerate chemical reactions, a fundamental pillar for the chemical industry. However, many fundamental questions remain about what actually happens inside the pores of a zeolite and, more precisely, how water influences the overall behaviour of the system.

Computer Science - Mathematics - 03.05.2021
USI develops innovative system for better credit card fraud detection
USI develops innovative system for better credit card fraud detection
The use of credit cards and other cashless or digital payment methods has become the norm for consumers all over the globe, and the strong surge of online buying during the pandemic has further boosted this decade-long trend. However, behind the convenience of 'click and pay' there are also risks, such as fraud and related losses, which are mostly borne by the card companies.

Life Sciences - 15.02.2021
New discovery at the IOR on mechanisms leading to the spread of metastases
New discovery at the IOR on mechanisms leading to the spread of metastases
Prostate cancer research is making further progress with a recent discovery of the Prostate Cancer Biology laboratory at the Institute of Oncology Research (IOR, affiliated to the Universitą della Svizzera Italiana). A study led by Dr  Giuseppina Carbone has revealed that micro-RNA fragments, released into the body by prostate cancer cells through microscopic vesicles called exosomes, lead to the formation of metastases.

Economics / Business - Innovation - 09.02.2021
Thematic ETFs,
Thematic ETFs, "a financial innovation gone awry"
Catering to the future expectations of investors is inherent to the world of finance which, as such, plays an import role in fostering economic growth through it's ability to innovate. However, financial innovations are not always flawless. A recent study co-authored by USI finance professor Francesco Franzoni reveals the significant performance inefficiencies of the increasingly popular 'thematic' exchange traded funds (ETFs).

Health - Pharmacology - 03.02.2021
Better poison dosages for better prostate cancer therapies
A given substance may be fundamental for life or may serve as a poison. All depends on the specific dose. At first glance, this somewhat paradoxical principle in medicine was first coined by the Swiss physician Paracelsus more than half a millennium ago when he stated: "All things are poison, and nothing is without poison.

Health - Career - 07.01.2021
Effectiveness of protective measures in hospitals in Ticino
A study performed in Ticino in Spring 2020, on data of SARS-CoV-2 serological tests run on healthcare workers, shows that COVID-19 antibodies are detectable in up to 10% of the participants. Such a result are comparable with the ones of the Corona Immunitas study conducted on the Ticino population. More importantly, it shows that healthcare workers with exposure to COVID-19 patients have only a slightly higher absolute risk of seropositivity than those without, suggesting that the use of protective measures in hospitals aiming at reducing nosocomial viral transmission are effective.

Health - Life Sciences - 30.12.2020
Moving towards new cancer therapies with computer simulations at IDSIA USI-SUPSI
Moving towards new cancer therapies with computer simulations at IDSIA USI-SUPSI
From a research hypothesis in experimental biology to the possible application in the field of anticancer therapies, through computer simulations. This is the essential course of an interdisciplinary and international research project that has identified the mechanisms by which particular peptides can penetrate cell membranes and contribute to the elimination of tumors.

Health - Pharmacology - 11.12.2020
A data-driven approach to identify risk profiles and protective drugs in COVID-19
A study performed in Ticino between Ente Ospedaliero Cantonale (EOC), USI Universitą della Svizzera italiana and Universitą Vita-Salute San Raffaele (UniSR, Milan, Italy) has shown how drugs against hypertension can reduce by more than 60% the risk of mortality in COVID-19 patients. The multidisciplinary study concerned 576 patients admitted to the EOC during the first wave of the epidemic, and was published in the prestigious journal Proceedings of the National Academy of Sciences (PNAS).

Earth Sciences - Computer Science - 23.11.2020
Safer geothermal energy thanks to supercomputers
Safer geothermal energy thanks to supercomputers
Make geothermal energy safer by using supercomputer simulations. That is the aim of the research project FASTER (Forecasting and Assessing Seismicity and Thermal Evolution in Geothermal Reservoirs) which involves Universitą della Svizzera italiana (USI), the Swiss Seismic Service (SED), the Swiss Federal Institute of Technology Zurich (ETH), and the Swiss National Centre for Scientific Computing (CSCS).
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