Blocking sugar metabolism slows lung tumour growth

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The ’G’ represents the highly expressed glucose transporters Glut1 a
The ’G’ represents the highly expressed glucose transporters Glut1 and Glut3 in lung adenocarcinomas. Left: the dual deletion impairing lung tumor growth. Credit: Liloon (Julie de Meyer)
The 'G' represents the highly expressed glucose transporters Glut1 and Glut3 in lung adenocarcinomas. Left: the dual deletion impairing lung tumor growth. Credit: Liloon (Julie de Meyer) - Treatments that block two sugar-transporting proteins could help slow the growth of lung tumours, new research from EPFL suggests. Blocking a pair of sugar-transporting proteins may be a useful treatment approach for lung cancer, suggests a new study in mice and human cells published today in eLife . Cancer cells use a lot of sugar to fuel their rapid growth and spread. This has led scientists to consider cutting off their sugar supply as a way to treat cancer. The current study suggests this could be an effective approach but it will be necessary to block multiple pathways at once to be effective.
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