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Health - Pharmacology - 16.06.2021
Immune defense: How immune cells are activated
Immune defense: How immune cells are activated
Immune cells protect our body against invading pathogens. The chemokine receptor CCR5 on the surface of T cells plays an important role in this process. However, CCR5 also is used by the HI-Virus as entrance gate into T cells. A research consortium led by the University of Basel has now deciphered the mechanism of CCR5 receptor activation.

Pharmacology - Health - 02.06.2021
Replicating patients' tumours to test different treatments
Replicating patients’ tumours to test different treatments
UNIGE Researchers have developed in vitro tumour models that incorporate components of the tumour and elements of the patient's immune system to test the effectiveness of treatments. Every tumour is different, every patient is different. So how do we know which treatment will work best for the patient and eradicate the cancer?

Pharmacology - Life Sciences - 01.06.2021
Protecting the IQ of people at risk for psychosis
Protecting the IQ of people at risk for psychosis
A team from the University of Geneva has found that a class of drugs can protect the development of intellectual abilities in people at risk of psychosis, if prescribed before adolescence. One person in 2000 suffers from a microdeletion of chromosome 22 that can lead to the development of psychotic disorders, such as schizophrenia, in adolescence.

Health - Pharmacology - 31.05.2021
Moving one step closer to personalized anesthesia
Moving one step closer to personalized anesthesia
Researchers have developed a device that can continuously measure the blood concentration of propofol - one of the main compounds used in anesthetics - in patients as they're being operated on. That will help anesthesiologists deliver more personalized doses. Anesthesia may be an exact science, but it's not yet fully personalized.

Health - Pharmacology - 27.05.2021
Cell encapsulation could enhance antiviral vaccines
Cell encapsulation could enhance antiviral vaccines
A team from the UNIGE and the HUG has developed a new and effective anti-viral vaccination technique based on the cell encapsulation. Immunotherapy techniques developed in oncology to combat cancerous cells have great potential for fighting viruses. A research team from the University Hospitals of Geneva (HUG) and the University of Geneva , in Switzerland, in collaboration with MaxiVAX, a spinoff of both institutions, developed an innovative technology called "cell encapsulation".

Health - Pharmacology - 18.05.2021
New Technology Makes Tumor Eliminate Itself
New Technology Makes Tumor Eliminate Itself
A new technology enables the body to produce therapeutic agents on demand at the exact location where they are needed. The innovation could reduce the side effects of cancer therapy and may hold the solution to better delivery of Covid-related therapies directly to the lungs. Scientists at the University of Zurich have modified a common respiratory virus, called adenovirus, to act like a Trojan horse to deliver genes for cancer therapeutics directly into tumor cells.

Health - Pharmacology - 06.05.2021
Biomarker Detects Severe COVID-19 Early On
Severe cases of COVID-19 can now be detected at an early stage. Researchers at the University of Zurich have identified the first biomarker that can reliably predict which patients will develop severe symptoms. This can help to improve the treatment of severe cases of COVID-19. Most people who are infected with SARS-CoV-2 develop no or only mild symptoms.

Health - Pharmacology - 03.05.2021
COVID-19 test detects antibodies in hundreds of tiny blood samples
COVID-19 test detects antibodies in hundreds of tiny blood samples
Antibody testing can be a powerful tool for tracking the spread of SARS-CoV2 infections, the virus responsible for the COVID-19 pandemic. A group of scientists from EPFL, UNIGE and HUG have now developed a reliable and cheap antibody test that can analyze more than 1,000 samples at once and requires a small drop of blood, such as that from a finger prick.

Health - Pharmacology - 03.05.2021
Cheap COVID-19 test detects antibodies blood drops
Cheap COVID-19 test detects antibodies blood drops
Antibody testing can be a powerful tool for tracking the spread of SARS-CoV2 infections, the virus responsible for the COVID-19 pandemic. A group of scientists from EPFL, UNIGE and HUG have now developed a reliable and cheap antibody test that can analyze more than 1,000 samples at once and requires a small drop of blood, such as that from a finger prick.

Pharmacology - Health - 22.04.2021
Stimulating the immune system with sponges made of silica
Stimulating the immune system with sponges made of silica
Silica nanoparticles developed by a team from the UNIGE and Ludwig-Maximilian University of Munich have significantly increased the effectiveness and precision of immunotherapies. Immunotherapies are increasingly used to fight cancer and aim to stimulate the immune system to defend itself by destroying tumour cells.

Health - Pharmacology - 21.04.2021
Targeted therapies thanks to biomedical informatics
Targeted therapies thanks to biomedical informatics
The new "LOOP Zurich - Medical Research Center" promotes patient-focused therapies - for example in oncology and neuro-rehabilitation. To achieve its goals, the center brings together specialist knowledge in the fields of biomedicine, clinical research and bioinformatics from the University of Zurich, ETH Zurich as well as Zurich's four university hospitals.

Pharmacology - Computer Science - 15.04.2021
Designing better antibody drugs with artificial intelligence
Machine learning methods help to optimise the development of antibody drugs. This leads to active substances with improved properties, also with regard to tolerability in the body. Antibodies are not only produced by our immune cells to fight viruses and other pathogens in the body. For a few decades now, medicine has also been using antibodies produced by biotechnology as drugs.

Health - Pharmacology - 13.04.2021
Parkinson's disease: wearable sensors to track symptoms
Scientists have developed algorithms that, combined with wearable sensors, could help clinicians to monitor the progression of Parkinson's disease and assess the effects of medications commonly used by people with this neurodegenerative disorder. Parkinson's disease affects neurons in an area of the brain that controls movement, causing tremors, difficulty walking and other motor problems.

Pharmacology - Health - 09.04.2021
Fighting dementia with play
Fighting dementia with play
Cognitive motor training helps in the fight against Alzheimer's and dementia, as demonstrated for the first time in a study by an international team of researchers with ETH Zurich involvement. The training platform used was developed by an ETH Zurich spin-off. A dementia diagnosis turns the world upside down, not only for the person affected but also for their relatives, as brain function gradually declines.

Health - Pharmacology - 08.04.2021
Veal calf fattening: it can work with less antibiotics
By adopting a few simple measures, farmers can drastically reduce the use of antibiotics and improve the well-being of their animals without economic disadvantages. This was confirmed in a field trial- the first of its kind in Switzerland - carried out by researchers of the University of Bern based on the specially developed "outdoor veal calf" method.

Health - Pharmacology - 31.03.2021
Promising Treatment Alternative Against Parasitic Worm Infection
Promising Treatment Alternative Against Parasitic Worm Infection
Strongyloidiasis, a parasitic worm infection caused by soil-transmitted helminths, remains a neglected public health problem with limited treatment options. Swiss TPH researchers conducted the first dose-finding study with moxidectin against strongyloidiasis. The drug could become a treatment alternative to the only treatment available so far and help fill the empty anthelminthic drug pipeline.

Health - Pharmacology - 15.03.2021
Retinal implants can give artificial vision to the blind
Retinal implants can give artificial vision to the blind
A team of EPFL engineers has developed technology that could partially restore vision in blind people. Being able to make blind people see again sounds like the stuff of miracles or even science fiction. And it has always been one of the biggest challenges for scientists. Diego Ghezzi, who holds the Medtronic Chair in Neuroengineering (LNE) at EPFL's School of Engineering, has made this issue a research focus.

Health - Pharmacology - 08.03.2021
Predicting success in therapy with individualized cancer models
Predicting success in therapy with individualized cancer models
Scientists at Urology Research Laboratory of the Department for BioMedical Research (DBMR), University of Bern and Urology Department of the Inselspital of Bern, have established organoid culture models from prostate tumor biopsies. These are small clusters of cells which can be used to test the efficacy of various drugs.

Health - Pharmacology - 05.03.2021
Controlling adhesions in the abdomen
Controlling adhesions in the abdomen
Adhesions are scars in the abdomen, which can occur after surgery, often have serious consequences. Now, researchers from the University of Bern and Inselspital, University Hospital Bern, in collaboration with Canadian researchers, have discovered how such adhesions form. The findings may help to develop a drug to prevent adhesions in the future.

Health - Pharmacology - 24.02.2021
Scientists model a peculiar type of breast cancer
Scientists model a peculiar type of breast cancer
Scientists led by EPFL have developed a breakthrough in vivo model for invasive lobular carcinoma, a serious yet understudied type of breast cancer. The work will open up previously inaccessible study of the tumor's biology and help discover new therapies. Invasive lobular carcinoma (ILC) is a type of breast cancer that begins in the milk-producing glands (lobules) of the breast.
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