Nanobodies (pink) in the wing precursor of a fruit fly larva. (Image: University of Basel, Biozentrum)
Researchers at the Biozentrum of the University of Basel have developed a new method by which proteins can be transported to a new location in a cell. The novel tool enables scientists to study the function of proteins depending on their position by using nanobodies. The tool can be used for a wide range of proteins and in various areas of developmental biology. The scientific journal eLife has published the results. The research group of Markus Affolter is investigating the growth of the wings of the fruit fly Drosophila to understand which processes control organ development and growth. Proteins that control such growth processes are the focus of their investigations. In this context, not only the composition of the proteins is important, but also their position which can influence protein function.
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