Squeezing cells into stem cells

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Illustration of an iPSC colony emerging in a 3D gel © Matthias Lutolf (EPFL)
Illustration of an iPSC colony emerging in a 3D gel © Matthias Lutolf (EPFL)
11. EPFL scientists have developed a new method that turns cells into stem cells by "squeezing" them. The method paves the way for large-scale production of stem cells for medical purposes. Stem cells are now at the cutting edge of modern medicine. They can transform into a cells of different organs, offering new ways to treat a range of injuries and diseases from Parkinson's to diabetes. But producing the right type of stem cells in a standardized manner is still a serious challenge. EPFL scientists have now developed a gel that boosts the ability of normal cells to revert into stem cells by simply "squeezing" them into shape.
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