Adipose tissue as a culprit: How obesity leads to diabetes

A high-fat diet leads to obesity and the development of diabetes. A research team at the University of Basel has discovered that a high-fat diet alters the function of adipose tissue, thus impairing its ability to regulate blood sugar. This explains why a high-fat diet poses a significant health risk, particularly for diabetes. Diabetes is a medical condition in which the body is unable to keep blood sugar in a healthy range. Normally, the pancreas produces sufficient insulin to regulate the blood sugar level and maintain homeostasis. However, in diabetics, the body has lost this ability, leading to hyperglycemia. Blood sugar levels that are persistently too high can cause long-term damage to blood vessels and lead to severe complications such as blindness or kidney failure.