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Without political measures for zero-emission technologies, a significant proportion of heavy goods vehicles will still run on diesel in 2035. This result is shown in a new ETH Zurich study on the decarbonisation of truck traffic. Without political incentives, heavy goods vehicles will probably continue to run on diesel in the future.

Researchers from the Department of Oncology UNIL-CHUV published a new study in Immunity, showing that machine learning improves the prioritization of cancer specific mutations for cancer immunotherapy. The study *, published in Immunity , was conducted by Markus Müller, a senior scientist in the Immunopeptidomics group headed by Michal Bassani-Sternberg, within the Human Integrated Tumor Immunology Discovery Engine (Hi-TIDe), part of the Ludwig Lausanne branch, which is directed by Pr George Coukos.

Professor Annegret Hannawa from USI Faculty of Communication, Culture and Society will conduct one of the sessions of the upcoming Arctic Circle Assembly in Reykjavík, Iceland. The conference is the largest annual international meeting on the Arctic, and over 700 speakers and more than 2000 participants from 60 countries are expected.

Basel-Landschaft schoolchildren say "ah": every year, the school dental service teaches proper dental hygiene and offers free examinations. A long-term study has now shown the effects these preventative measures have had on dental health and which children continue to be at risk. The first cavity-prevention programs in Switzerland go back to the 1960s.

Cancer cells are chameleons. They completely change their metabolism to grow continuously. University of Basel scientists have discovered that high levels of the amino acid arginine drive metabolic reprogramming to promote tumor growth. This study suggests new avenues to improve liver cancer treatment.

Parithera, an EPFL spin-off, has developed a system that lets doctors detect drug resistance in cancer patients early on, saving precious time and preventing the unnecessary use of treatments with onerous side effects. Drug resistance is a major problem in the treatment of cancer. Some cancer cells demonstrate resistance right at the start of a new therapy, while others develop it over the course of several months or years.

Around 45 percent of the Swiss population is considering moving. More than half of them would like more living space. This is shown by a study conducted by the ZHAW in collaboration with the Federal Office of Housing, the Fédération Romande Immobilière, the Swiss Homeowners Association and Raiffeisen Switzerland .

As we age, many of us will eventually need hearing aids. In some cases, the reason for this may be a signaling pathway that controls auditory sensory cell function and is downregulated with age. Researchers at the University of Basel are uncovering clues. Hearing loss eventually affects almost everyone: Loud noises or simple aging gradually cause the auditory sensory cells and their synapses in the inner ear to degenerate and die off.

Stimulating the brain with gentle sounds during deep sleep significantly enhances cardiac function, according to a new study. This discovery could have implications not only for cardiovascular diseases but also for competitive sports, among other areas. Sleep is a vital aspect of human life, with deep sleep being particularly crucial for overall health.

Researchers from Zurich have used machine learning to jointly create an innovative method. This new approach can predict how individual cells react to specific treatments, offering hope for more accurate diagnoses and therapeutics. Cancer is triggered by changes in cells that lead to the proliferation of pathogenic tumour cells.

Scientists at EPFL have synthesized the first ever metal-organic frameworks membrane with thickness of just one unit cell. The ultrathin film yields record-high separation performance of hydrogen-nitrogen. Metal-organic frameworks (MOFs) are a class of materials that contain nano-sized pores. These pores give MOFs record-breaking internal surface areas, which make them extremely versatile for a number of applications: separating petrochemicals and gases , mimicking DNA , producing hydrogen , and removing heavy metals , fluoride anions , and even gold from water are just a few examples.

Scientists at EPFL have synthesized the first ever metal-organic frameworks membrane with thickness of just one unit cell. The ultrathin film yields record-high separation performance of hydrogen. Metal-organic frameworks (MOFs) are a class of materials that contain nano-sized pores. These pores give MOFs record-breaking internal surface areas, which make them extremely versatile for a number of applications: separating petrochemicals and gases , mimicking DNA , producing hydrogen , and removing heavy metals , fluoride anions , and even gold from water are just a few examples.

Despite leaving behind thousands of deformed infants, thalidomide — and newer drugs derived from it — have proved effective cancer treatments. Researchers in the group of Nicolas Thomä at the FMI provided key insights into the mechanism of action of thalidomide-like drugs. Their work could help develop molecules that target and destroy disease-causing proteins, thus enabling the treatment of uncurable conditions.

When it comes to feeding a growing population at a time of conflict and climate change, Mother Earth has a lot on her plate. To build a sustainable future we'll need to return to a farm-to-table model, and that's opening up vast and exciting avenues of research for scientists in an array of fields. In this special report , we explore some of the developments taking place in research labs and out on the farm.

Researchers show in a new study that a short reflection exercise to boost self confidence increases job search success. This holds true even for the long-term unemployed and people over 50. For many people, losing their job is not only a financial burden but also a psychological one. They are stressed, worry about their social status and begin to doubt themselves.

Cell biologists at ETH Zurich describe a new organelle present in mammalian cells that is made of rings of DNA. This "mini-organ" could potentially play a role in autoimmune diseases, and it could help researchers to understand how cell nuclei evolved. (Illustration: The nucleus recognizes plasmids (DNA rings, pictured) and shuttles them into the cytoplasm, where they become part of a newly discovered organelle, the exclosome.

Cell biologists at ETH Zurich describe a new organelle present in mammalian cells that is made of rings of DNA. This "mini-organ" could potentially play a role in autoimmune diseases, and it could help researchers to understand how cell nuclei evolved. (Illustration: The nucleus recognizes plasmids (DNA rings, pictured) and shuttles them into the cytoplasm, where they become part of a newly discovered organelle, the exclosome.

Scientists at EPFL use cutting-edge imaging techniques to shed light on the progression of Parkinson's disease by studying how the main culprit, the protein alpha-synuclein, disrupts cellular metabolism. Parkinson's disease is a complex neurodegenerative disorder that leads to the deterioration of specific types of neurons in the brain, resulting in a number of motor and non-motor symptoms.

A team from the University of Geneva shows that disruptions to the circadian clock increase the risk of developing a neurodegenerative disease. Disturbances in sleep patterns and the internal biological clock are frequently associated with Parkinson's disease. However, the link between biological rhythm and neuronal degeneration remains unclear.

Researchers at ETH Zurich have developed a suction cup that allows medications to be absorbed through the mucosal lining of the cheeks. This new approach could spare millions of patients the pain and fear associated with injections. Many of today's medications belong to groups of relatively large molecules such as peptides.